Details for: O fut1

Gene ID: 36564

Symbol: O fut1

Ensembl ID: FBgn0033901

Description: O-fucosyltransferase 1

Associated with

Other Information

Genular Protein ID: 3071571493

Symbol: OFUT1_DROME

Name: GDP-fucose protein O-fucosyltransferase 1

UniProtKB Accession Codes:

Q9V6X7 Q5BIC9 Q86SA7 Q8MSR1

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CAZy 1 CDD 1 CTD 1 ChEBI 10 DIP 1 DNASU 1 EC 2 EMBL 4 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 11 Gene3D 2 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 2 Rhea 8 SMR 1 STRING 1 SignaLink 1 UniPathway 1 UniProtKB 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 12917292

Title: Neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions.

PubMed ID: 12917292

DOI: 10.1242/dev.00679

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11524432

Title: Modification of epidermal growth factor-like repeats with O-fucose: molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase.

PubMed ID: 11524432

DOI: 10.1074/jbc.m107849200

PubMed ID: 11698403

Title: Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.

PubMed ID: 11698403

DOI: 10.1074/jbc.m107927200

PubMed ID: 12909620

Title: Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.

PubMed ID: 12909620

DOI: 10.1074/jbc.m308687200

PubMed ID: 17329366

Title: The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila.

PubMed ID: 17329366

DOI: 10.1242/dev.02811

Sequence Information:

  • Length: 402
  • Mass: 46834
  • Checksum: E52FF4F86509C2E6
  • Sequence:
    • MQWLKMKLRF VNLILLLISS TCAQLGGDPN GYLTYCPCMG RFGNQADHFL GSLAFAKALN 
RTLILPPWVE YRRGELRSRQ VPFNTYFEVE PLKEYHRVIT MADFMWHLAD DIWPESERVS 
FCYKERYSLQ QEKNDPDKPN CHAKDGNPFG PFWDTFHIDF VRSEFYAPLH FDVHHSNEAA 
KWQTKYPAES YPVLAFTGAP ASFPVQLENC KLQRYLQWSQ RYREASKDFI REQLPRGAFL 
GIHLRNGIDW VRACEHVKDS QHLFASPQCL GYKNERGALY PELCMPSKEA IIRQLKRTIK 
NVRQTQPDNE IKSVFVASDS NHMIGELNTA LSRMGISVHK LPEDDPYLDL AILGQSNHFI 
GNCISSYSAF EKRERDVHGF PSYFWGFPKE KDRKHTNVHE EL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.