Associated with
Other Information
Genular Protein ID: 3185806052
Symbol: EXT1_DROME
Name: Exostosin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9665133
Title: Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion.
PubMed ID: 9665133
DOI: 10.1038/27932
PubMed ID: 16303756
Title: Heparan sulfate polymerization in Drosophila.
PubMed ID: 16303756
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 10549295
Title: Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan.
PubMed ID: 10549295
PubMed ID: 10644674
Title: Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo.
PubMed ID: 10644674
PubMed ID: 10806213
Title: Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes.
PubMed ID: 10806213
PubMed ID: 12586063
Title: Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog.
PubMed ID: 12586063
PubMed ID: 14645127
Title: Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.
PubMed ID: 14645127
DOI: 10.1242/dev.00913
PubMed ID: 14729575
Title: Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process.
PubMed ID: 14729575
DOI: 10.1242/dev.00958
PubMed ID: 14998928
Title: Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation.
PubMed ID: 14998928
DOI: 10.1242/dev.01051
PubMed ID: 15056609
Title: Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways.
PubMed ID: 15056609
DOI: 10.1242/dev.01061
PubMed ID: 23720043
Title: The Drosophila GOLPH3 homolog regulates the biosynthesis of heparan sulfate proteoglycans by modulating the retrograde trafficking of exostosins.
PubMed ID: 23720043
DOI: 10.1242/dev.087171
Sequence Information:
- Length: 760
- Mass: 87309
- Checksum: F6369F0BA206DEA9
- Sequence:
MQAKKRYILV FVSCAFLAYA YFGGYRLKVS PLRPRRAQHE SAKDGGVQPH EQLPSFLGAH DMQELQLLQS NQSKSLDSSK HLVTRKPDCR METCFDFTRC YDRFLVYIYP PEPLNSLGAA PPTSANYQKI LTAIQESRYY TSDPTAACLF VLGIDTLDRD SLSEDYVRNV PSRLARLPYW NNGRNHIIFN LYSGTWPDYA ENSLGFDAGE AILAKASMGV LQLRHGFDVS IPLFHKQFPL RAGATGTVQS NNFPANKKYL LAFKGKRYVH GIGSETRNSL FHLHNGRDMV LVTTCRHGKS WRELQDNRCD EDNREYDRYD YETLLQNSTF CLVPRGRRLG SFRFLEALQA GCIPVLLSNA WVLPFESKID WKQAAIWADE RLLLQVPDIV RSIPAERIFA LRQQTQVLWE RYFGSIEKIV FTTFEIIRER LPDYPVRSSL VWNSSPGALL TLPTFADSSR YMPFLLNSMG AEPRHNYTAV IYVQIGAALG PNAALYKLVR TITKSQFVER ILVLWAADRP LPLKKRWPPT SHIPLHVISL GGSTRSQGAG PTSQTTEGRP SISQRFLPYD EIQTDAVLSL DEDAILNTDE LDFAYTVWRD FPERIVGYPA RAHFWDDSKN AWGYTSKWTN YYSIVLTGAA FYHRYYNYLY TNWLSLLLLK TVQQSSNCED ILMNLLVSHV TRKPPIKVTQ RKGYKDRETG RSPWNDPDHF IQRQSCLNTF AAVFGYMPLI RSNLRMDPML YRDPVSNLRK KYRQIELVGS
Genular Protein ID: 3433991445
Symbol: D5SHU8_DROME
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10731132
Title: The genome sequence of Drosophila melanogaster.
PubMed ID: 10731132
PubMed ID: 12537568
Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.
PubMed ID: 12537568
PubMed ID: 12537572
Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
PubMed ID: 12537572
PubMed ID: 12537573
Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.
PubMed ID: 12537573
PubMed ID: 12537574
Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.
PubMed ID: 12537574
PubMed ID: 16110336
Title: Combined evidence annotation of transposable elements in genome sequences.
PubMed ID: 16110336
PubMed ID: 17569856
Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
PubMed ID: 17569856
PubMed ID: 17569867
Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
PubMed ID: 17569867
PubMed ID: 26109357
Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
PubMed ID: 26109357
DOI: .1534/g3.115.018929
PubMed ID: 26109356
Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
PubMed ID: 26109356
DOI: .1534/g3.115.018937
PubMed ID: 25589440
Title: The Release 6 reference sequence of the Drosophila melanogaster genome.
PubMed ID: 25589440
Sequence Information:
- Length: 299
- Mass: 34443
- Checksum: 4388AE88E6914EAB
- Sequence:
MPFLLNSMGA EPRHNYTAVI YVQIGAALGP NAALYKLVRT ITKSQFVERI LVLWAADRPL PLKKRWPPTS HIPLHVISLG GSTRSQGAGP TSQTTEGRPS ISQRFLPYDE IQTDAVLSLD EDAILNTDEL DFAYTVWRDF PERIVGYPAR AHFWDDSKNA WGYTSKWTNY YSIVLTGAAF YHRYYNYLYT NWLSLLLLKT VQQSSNCEDI LMNLLVSHVT RKPPIKVTQR KGYKDRETGR SPWNDPDHFI QRQSCLNTFA AVFGYMPLIR SNLRMDPMLY RDPVSNLRKK YRQIELVGS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.