Details for: tra2

Gene ID: 36619

Symbol: tra2

Ensembl ID: FBgn0003742

Description: transformer 2

Associated with

Other Information

Genular Protein ID: 3554667038

Symbol: TRA2_DROME

Name: Transformer-2 sex-determining protein

UniProtKB Accession Codes:

P19018 A4UZH1 Q0E977 Q9V734

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 EMBL 15 EnsemblMetazoa 7 FlyBase 1 GO 19 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 3 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 4 RefSeq 7 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 3144434

Title: The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein.

PubMed ID: 3144434

DOI: 10.1016/0092-8674(88)90247-4

PubMed ID: 2120049

Title: Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size.

PubMed ID: 2120049

DOI: 10.1002/j.1460-2075.1990.tb07573.x

PubMed ID: 2116360

Title: Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma.

PubMed ID: 2116360

DOI: 10.1101/gad.4.5.789

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 2493992

Title: The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins.

PubMed ID: 2493992

DOI: 10.1016/0092-8674(89)90634-x

PubMed ID: 1674449

Title: Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro.

PubMed ID: 1674449

DOI: 10.1016/0092-8674(91)90090-l

PubMed ID: 8334698

Title: A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA.

PubMed ID: 8334698

DOI: 10.1016/0092-8674(93)90298-5

PubMed ID: 8124712

Title: The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2.

PubMed ID: 8124712

DOI: 10.1016/0092-8674(94)90512-6

PubMed ID: 7867927

Title: Synergistic interactions between two distinct elements of a regulated splicing enhancer.

PubMed ID: 7867927

DOI: 10.1101/gad.9.3.284

PubMed ID: 9418892

Title: Regulation of sex-specific selection of fruitless 5' splice sites by transformer and transformer-2.

PubMed ID: 9418892

DOI: 10.1128/mcb.18.1.450

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 264
  • Mass: 31031
  • Checksum: 3BECBD694B0817B3
  • Sequence:
    • MDREPLSSGR LHCSARYKHK RSASSSSAGT TSSGHKDRRS DYDYCGSRRH QRSSSRRRSR 
SRSSSESPPP EPRHRSGRSS RDRERMHKSR EHPQASRCIG VFGLNTNTSQ HKVRELFNKY 
GPIERIQMVI DAQTQRSRGF CFIYFEKLSD ARAAKDSCSG IEVDGRRIRV DFSITQRAHT 
PTPGVYLGRQ PRGKAPRSFS PRRGRRVYHD RSASPYDNYR DRYDYRNDRY DRNLRRSPSR 
NRYTRNRSYS RSRSPQLRRT SSRY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.