Details for: Dro

Gene ID: 36635

Symbol: Dro

Ensembl ID: FBgn0010388

Description: Drosocin

Associated with

  • Antibacterial humoral response
    (GO:0019731)
  • Defense response
    (GO:0006952)
  • Defense response to bacterium
    (GO:0042742)
  • Defense response to gram-negative bacterium
    (GO:0050829)
  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Defense response to insect
    (GO:0002213)
  • Extracellular region
    (GO:0005576)
  • Positive regulation of biosynthetic process of antibacterial peptides active against gram-negative bacteria
    (GO:0006964)
  • Response to bacterium
    (GO:0009617)

Other Information

Genular Protein ID: 1097123568

Symbol: DROS_DROME

Name: N/A

UniProtKB Accession Codes:

P36193 Q53ZZ5 Q867T5 Q86BV9 Q9V749

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 36 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 10 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PDB 9 PDBsum 6 PIR 1 PRO 1 PaxDb 1 PhylomeDB 1 Proteomes 1 RefSeq 2 SMR 1 STRING 1 VEuPathDB 1 iPTMnet 1

Citations:

PubMed ID: 8325867

Title: A novel inducible antibacterial peptide of Drosophila carries an O-glycosylated substitution.

PubMed ID: 8325867

DOI: 10.1016/s0021-9258(18)82417-6

PubMed ID: 8944755

Title: Cloning of the gene encoding the antibacterial peptide drosocin involved in Drosophila immunity. Expression studies during the immune response.

PubMed ID: 8944755

DOI: 10.1111/j.1432-1033.1996.00699.x

PubMed ID: 12716986

Title: Molecular population genetics of inducible antibacterial peptide genes in Drosophila melanogaster.

PubMed ID: 12716986

DOI: 10.1093/molbev/msg109

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 9736738

Title: Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study.

PubMed ID: 9736738

DOI: 10.1073/pnas.95.19.11342

PubMed ID: 35730150

Title: Drosophila immunity: the Drosocin gene encodes two host defence peptides with pathogen-specific roles.

PubMed ID: 35730150

DOI: 10.1098/rspb.2022.0773

PubMed ID: 36997647

Title: Inhibition of translation termination by the antimicrobial peptide Drosocin.

PubMed ID: 36997647

DOI: 10.1038/s41589-023-01300-x

PubMed ID: 9888811

Title: Conformational studies by NMR of the antimicrobial peptide, drosocin, and its non-glycosylated derivative: effects of glycosylation on solution conformation.

PubMed ID: 9888811

DOI: 10.1021/bi981956d

PubMed ID: 36997646

Title: Structural basis for translation inhibition by the glycosylated drosocin peptide.

PubMed ID: 36997646

DOI: 10.1038/s41589-023-01293-7

Sequence Information:

  • Length: 64
  • Mass: 7085
  • Checksum: D715F5BA52FDAD17
  • Sequence:
    • MKFTIVFLLL ACVFAMGVAT PGKPRPYSPR PTSHPRPIRV RREALAIEDH LTQAAIRPPP 
ILPA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.