Details for: AR

Gene ID: 367

Symbol: AR

Ensembl ID: ENSG00000169083

Description: androgen receptor

Associated with

  • Activated pkn1 stimulates transcription of ar (androgen receptor) regulated genes klk2 and klk3
    (R-HSA-5625886)
  • Cellular responses to stimuli
    (R-HSA-8953897)
  • Cellular responses to stress
    (R-HSA-2262752)
  • Deubiquitination
    (R-HSA-5688426)
  • Gene expression (transcription)
    (R-HSA-74160)
  • Generic transcription pathway
    (R-HSA-212436)
  • Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
    (R-HSA-3371497)
  • Metabolism of proteins
    (R-HSA-392499)
  • Nuclear receptor transcription pathway
    (R-HSA-383280)
  • Post-translational protein modification
    (R-HSA-597592)
  • Rho gtpase effectors
    (R-HSA-195258)
  • Rho gtpases activate pkns
    (R-HSA-5625740)
  • Rna polymerase ii transcription
    (R-HSA-73857)
  • Runx2 regulates bone development
    (R-HSA-8941326)
  • Runx2 regulates osteoblast differentiation
    (R-HSA-8940973)
  • Signaling by rho gtpases
    (R-HSA-194315)
  • Signaling by rho gtpases, miro gtpases and rhobtb3
    (R-HSA-9716542)
  • Sumo e3 ligases sumoylate target proteins
    (R-HSA-3108232)
  • Sumoylation
    (R-HSA-2990846)
  • Sumoylation of intracellular receptors
    (R-HSA-4090294)
  • Transcriptional regulation by runx2
    (R-HSA-8878166)
  • Ub-specific processing proteases
    (R-HSA-5689880)
  • Activation of prostate induction by androgen receptor signaling pathway
    (GO:0060520)
  • Androgen binding
    (GO:0005497)
  • Androgen receptor signaling pathway
    (GO:0030521)
  • Animal organ formation
    (GO:0048645)
  • Atpase binding
    (GO:0051117)
  • Beta-catenin binding
    (GO:0008013)
  • Cell-cell signaling
    (GO:0007267)
  • Chromatin binding
    (GO:0003682)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Enzyme binding
    (GO:0019899)
  • Epithelial cell differentiation involved in prostate gland development
    (GO:0060742)
  • Epithelial cell morphogenesis
    (GO:0003382)
  • Epithelial cell proliferation
    (GO:0050673)
  • Estrogen response element binding
    (GO:0034056)
  • G protein-coupled receptor activity
    (GO:0004930)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • Insulin-like growth factor receptor signaling pathway
    (GO:0048009)
  • Intracellular estrogen receptor signaling pathway
    (GO:0030520)
  • Intracellular receptor signaling pathway
    (GO:0030522)
  • Intracellular steroid hormone receptor signaling pathway
    (GO:0030518)
  • In utero embryonic development
    (GO:0001701)
  • Lateral sprouting involved in mammary gland duct morphogenesis
    (GO:0060599)
  • Leydig cell differentiation
    (GO:0033327)
  • Male genitalia morphogenesis
    (GO:0048808)
  • Male gonad development
    (GO:0008584)
  • Male somatic sex determination
    (GO:0019102)
  • Mammary gland alveolus development
    (GO:0060749)
  • Mapk cascade
    (GO:0000165)
  • Molecular adaptor activity
    (GO:0060090)
  • Morphogenesis of an epithelial fold
    (GO:0060571)
  • Multicellular organism growth
    (GO:0035264)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of epithelial cell proliferation
    (GO:0050680)
  • Negative regulation of integrin biosynthetic process
    (GO:0045720)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nuclear receptor activity
    (GO:0004879)
  • Positive regulation of cell differentiation
    (GO:0045597)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of epithelial cell proliferation involved in prostate gland development
    (GO:0060769)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043568)
  • Positive regulation of integrin biosynthetic process
    (GO:0045726)
  • Positive regulation of intracellular estrogen receptor signaling pathway
    (GO:0033148)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Positive regulation of nf-kappab transcription factor activity
    (GO:0051092)
  • Positive regulation of phosphorylation
    (GO:0042327)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Positive regulation of transcription by rna polymerase iii
    (GO:0045945)
  • Pou domain binding
    (GO:0070974)
  • Prostate gland epithelium morphogenesis
    (GO:0060740)
  • Prostate gland growth
    (GO:0060736)
  • Protein binding
    (GO:0005515)
  • Regulation of developmental growth
    (GO:0048638)
  • Regulation of systemic arterial blood pressure
    (GO:0003073)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii general transcription initiation factor binding
    (GO:0001091)
  • Signaling receptor binding
    (GO:0005102)
  • Signal transduction
    (GO:0007165)
  • Single fertilization
    (GO:0007338)
  • Spermatogenesis
    (GO:0007283)
  • Steroid binding
    (GO:0005496)
  • Tertiary branching involved in mammary gland duct morphogenesis
    (GO:0060748)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Transcription coactivator binding
    (GO:0001223)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 3111552214

Symbol: ANDR_HUMAN

Name: Androgen receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3216866

Title: The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate.

PubMed ID: 3216866

DOI: 10.1210/mend-2-12-1265

PubMed ID: 3174628

Title: Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.

PubMed ID: 3174628

DOI: 10.1073/pnas.85.19.7211

PubMed ID: 2911578

Title: Characterization and expression of a cDNA encoding the human androgen receptor.

PubMed ID: 2911578

DOI: 10.1073/pnas.86.1.327

PubMed ID: 2594783

Title: Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

PubMed ID: 2594783

DOI: 10.1073/pnas.86.23.9534

PubMed ID: 2342476

Title: Specific region in hormone binding domain is essential for hormone binding and trans-activation by human androgen receptor.

PubMed ID: 2342476

DOI: 10.1210/mend-4-3-417

PubMed ID: 2293020

Title: Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance.

PubMed ID: 2293020

DOI: 10.1210/mend-4-8-1105

PubMed ID: 15634333

Title: Androgen receptor function is modulated by the tissue-specific AR45 variant.

PubMed ID: 15634333

DOI: 10.1111/j.1742-4658.2004.04395.x

PubMed ID: 19244107

Title: A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth.

PubMed ID: 19244107

DOI: 10.1158/0008-5472.can-08-3795

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2917688

Title: The N-terminal domain of the human androgen receptor is encoded by one, large exon.

PubMed ID: 2917688

DOI: 10.1016/0303-7207(89)90137-8

PubMed ID: 3353726

Title: Molecular cloning of human and rat complementary DNA encoding androgen receptors.

PubMed ID: 3353726

DOI: 10.1126/science.3353726

PubMed ID: 3377788

Title: Cloning, structure and expression of a cDNA encoding the human androgen receptor.

PubMed ID: 3377788

DOI: 10.1016/s0006-291x(88)81214-2

PubMed ID: 2546571

Title: Structural organization of the human androgen receptor gene.

PubMed ID: 2546571

DOI: 10.1677/jme.0.002r001

PubMed ID: 8413310

Title: A point mutation in the second zinc finger of the DNA-binding domain of the androgen receptor gene causes complete androgen insensitivity in two siblings with receptor-positive androgen resistance.

PubMed ID: 8413310

DOI: 10.1210/mend.7.7.8413310

PubMed ID: 3353727

Title: Cloning of human androgen receptor complementary DNA and localization to the X chromosome.

PubMed ID: 3353727

DOI: 10.1126/science.3353727

PubMed ID: 1775137

Title: Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics.

PubMed ID: 1775137

DOI: 10.1210/mend-5-10-1562

PubMed ID: 1561105

Title: Trinucleotide repeat polymorphism in the androgen receptor gene (AR).

PubMed ID: 1561105

DOI: 10.1093/nar/20.6.1427-a

PubMed ID: 9096391

Title: The CAG repeat within the androgen receptor gene and its relationship to prostate cancer.

PubMed ID: 9096391

DOI: 10.1073/pnas.94.7.3320

PubMed ID: 10332029

Title: PQBP-1, a novel polyglutamine tract binding protein, inhibits transcription activation by Brn-2 and affects cell survival.

PubMed ID: 10332029

DOI: 10.1093/hmg/8.6.977

PubMed ID: 10075738

Title: Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate.

PubMed ID: 10075738

DOI: 10.1074/jbc.274.12.8316

PubMed ID: 10383460

Title: Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription.

PubMed ID: 10383460

DOI: 10.1074/jbc.274.27.19441

PubMed ID: 10400640

Title: The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator.

PubMed ID: 10400640

DOI: 10.1074/jbc.274.29.20229

PubMed ID: 10625666

Title: PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression.

PubMed ID: 10625666

DOI: 10.1074/jbc.275.2.1216

PubMed ID: 10930412

Title: Androgen receptor interacts with a novel MYST protein, HBO1.

PubMed ID: 10930412

DOI: 10.1074/jbc.m004838200

PubMed ID: 11121022

Title: Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

PubMed ID: 11121022

DOI: 10.1073/pnas.97.26.14145

PubMed ID: 12361945

Title: RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor.

PubMed ID: 12361945

DOI: 10.1074/jbc.m209741200

PubMed ID: 12039962

Title: Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor.

PubMed ID: 12039962

DOI: 10.1074/jbc.m203811200

PubMed ID: 12415108

Title: Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade.

PubMed ID: 12415108

DOI: 10.1073/pnas.192569699

PubMed ID: 19666546

Title:

PubMed ID: 19666546

DOI: 10.1073/pnas.0908685106

PubMed ID: 14609956

Title: hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci.

PubMed ID: 14609956

DOI: 10.1093/emboj/cdg585

PubMed ID: 12958311

Title: The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway.

PubMed ID: 12958311

DOI: 10.1074/jbc.m306219200

PubMed ID: 14664718

Title: The retinoblastoma protein-associated transcription repressor RBaK interacts with the androgen receptor and enhances its transcriptional activity.

PubMed ID: 14664718

DOI: 10.1677/jme.0.0310583

PubMed ID: 12612053

Title: DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex.

PubMed ID: 12612053

PubMed ID: 14573606

Title: Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling.

PubMed ID: 14573606

DOI: 10.1074/jbc.m311145200

PubMed ID: 16027218

Title: Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.

PubMed ID: 16027218

DOI: 10.1083/jcb.200503106

PubMed ID: 16051670

Title: hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes.

PubMed ID: 16051670

DOI: 10.1210/me.2005-0097

PubMed ID: 17045208

Title: Regulation of androgen receptor activity by tyrosine phosphorylation.

PubMed ID: 17045208

DOI: 10.1016/j.ccr.2006.08.021

PubMed ID: 16951154

Title: Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells.

PubMed ID: 16951154

DOI: 10.1158/0008-5472.can-06-1636

PubMed ID: 17587566

Title: PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor.

PubMed ID: 17587566

DOI: 10.1016/j.jsbmb.2007.05.006

PubMed ID: 17550981

Title: The zinc finger protein Ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic signaling in prostate cancer.

PubMed ID: 17550981

DOI: 10.1210/me.2006-0503

PubMed ID: 18222118

Title: RanBP10 acts as a novel coactivator for the androgen receptor.

PubMed ID: 18222118

DOI: 10.1016/j.bbrc.2008.01.072

PubMed ID: 17494760

Title: Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation.

PubMed ID: 17494760

DOI: 10.1073/pnas.0700420104

PubMed ID: 18451177

Title: TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells.

PubMed ID: 18451177

DOI: 10.1158/0008-5472.can-07-6059

PubMed ID: 18451096

Title: Leupaxin, a novel coactivator of the androgen receptor, is expressed in prostate cancer and plays a role in adhesion and invasion of prostate carcinoma cells.

PubMed ID: 18451096

DOI: 10.1210/me.2006-0546

PubMed ID: 18084323

Title: ZIP kinase plays a crucial role in androgen receptor-mediated transcription.

PubMed ID: 18084323

DOI: 10.1038/sj.onc.1210995

PubMed ID: 19909775

Title: TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.

PubMed ID: 19909775

DOI: 10.1016/j.bbamcr.2009.11.001

PubMed ID: 19345326

Title: Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

PubMed ID: 19345326

DOI: 10.1016/j.ccr.2009.02.021

PubMed ID: 19022849

Title: The single-macro domain protein LRP16 is an essential cofactor of androgen receptor.

PubMed ID: 19022849

DOI: 10.1677/erc-08-0150

PubMed ID: 20980437

Title: CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.

PubMed ID: 20980437

DOI: 10.1210/me.2010-0238

PubMed ID: 20501646

Title: The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

PubMed ID: 20501646

DOI: 10.1158/1541-7786.mcr-09-0424

PubMed ID: 20623637

Title: Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity.

PubMed ID: 20623637

DOI: 10.1002/pros.21163

PubMed ID: 21512132

Title: MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.

PubMed ID: 21512132

DOI: 10.1158/0008-5472.can-10-4532

PubMed ID: 20812024

Title: FBI-1 functions as a novel AR co-repressor in prostate cancer cells.

PubMed ID: 20812024

DOI: 10.1007/s00018-010-0511-7

PubMed ID: 22170608

Title: Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.

PubMed ID: 22170608

DOI: 10.1038/nature10700

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22031296

Title: DHHC-7 and -21 are palmitoylacyltransferases for sex steroid receptors.

PubMed ID: 22031296

DOI: 10.1091/mbc.e11-07-0638

PubMed ID: 23887938

Title: CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2.

PubMed ID: 23887938

DOI: 10.1093/nar/gkt644

PubMed ID: 23487765

Title: ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.

PubMed ID: 23487765

DOI: 10.1073/pnas.1218318110

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10840043

Title: Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations.

PubMed ID: 10840043

DOI: 10.1074/jbc.m004571200

PubMed ID: 11906285

Title: Structural basis for the glucocorticoid response in a mutant human androgen receptor (AR(ccr)) derived from an androgen-independent prostate cancer.

PubMed ID: 11906285

DOI: 10.1021/jm011072j

PubMed ID: 15525515

Title: Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance.

PubMed ID: 15525515

DOI: 10.1016/j.molcel.2004.09.036

PubMed ID: 15563469

Title: The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor.

PubMed ID: 15563469

DOI: 10.1074/jbc.m407046200

PubMed ID: 16129672

Title: Structural basis for accommodation of nonsteroidal ligands in the androgen receptor.

PubMed ID: 16129672

DOI: 10.1074/jbc.m507464200

PubMed ID: 16641486

Title: Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.

PubMed ID: 16641486

DOI: 10.1110/ps.051905906

PubMed ID: 18007036

Title: Interaction between the androgen receptor and a segment of its corepressor SHP.

PubMed ID: 18007036

DOI: 10.1107/s0907444907045702

PubMed ID: 17311914

Title: Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.

PubMed ID: 17311914

DOI: 10.1074/jbc.m611711200

PubMed ID: 17591767

Title: Modulation of androgen receptor activation function 2 by testosterone and dihydrotestosterone.

PubMed ID: 17591767

DOI: 10.1074/jbc.m703268200

PubMed ID: 17711855

Title: Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12.

PubMed ID: 17711855

DOI: 10.1074/jbc.m705524200

PubMed ID: 17911242

Title: A surface on the androgen receptor that allosterically regulates coactivator binding.

PubMed ID: 17911242

DOI: 10.1073/pnas.0708036104

PubMed ID: 25091737

Title: Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.

PubMed ID: 25091737

DOI: 10.1016/j.molonc.2014.06.009

PubMed ID: 1458719

Title: Androgen resistance due to mutation of the androgen receptor.

PubMed ID: 1458719

PubMed ID: 8339746

Title: Molecular genetics of human androgen insensitivity.

PubMed ID: 8339746

DOI: 10.1007/bf02125442

PubMed ID: 8240973

Title: Mutations of androgen receptor gene in androgen insensitivity syndromes.

PubMed ID: 8240973

DOI: 10.1016/0960-0760(93)90178-y

PubMed ID: 7937057

Title: The androgen receptor gene mutations database.

PubMed ID: 7937057

PubMed ID: 7626493

Title: Androgen receptor mutations.

PubMed ID: 7626493

DOI: 10.1016/0960-0760(95)00090-m

PubMed ID: 9016528

Title: The androgen receptor gene mutations database.

PubMed ID: 9016528

DOI: 10.1093/nar/25.1.158

PubMed ID: 22334387

Title: The androgen receptor gene mutations database: 2012 update.

PubMed ID: 22334387

DOI: 10.1002/humu.22046

PubMed ID: 2260966

Title: A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens.

PubMed ID: 2260966

DOI: 10.1016/s0006-291x(05)80067-1

PubMed ID: 2082179

Title: Functional characterization of naturally occurring mutant androgen receptors from subjects with complete androgen insensitivity.

PubMed ID: 2082179

DOI: 10.1210/mend-4-12-1759

PubMed ID: 1856263

Title: Androgen resistance associated with a mutation of the androgen receptor at amino acid 772 (Arg-->Cys) results from a combination of decreased messenger ribonucleic acid levels and impairment of receptor function.

PubMed ID: 1856263

DOI: 10.1210/jcem-73-2-318

PubMed ID: 1999491

Title: A mutation in the DNA-binding domain of the androgen receptor gene causes complete testicular feminization in a patient with receptor-positive androgen resistance.

PubMed ID: 1999491

DOI: 10.1172/jci115076

PubMed ID: 2010552

Title: Molecular basis of androgen resistance in a family with a qualitative abnormality of the androgen receptor and responsive to high-dose androgen therapy.

PubMed ID: 2010552

DOI: 10.1172/jci115147

PubMed ID: 2062380

Title: Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy.

PubMed ID: 2062380

DOI: 10.1038/352077a0

PubMed ID: 1609793

Title: Replacement of arginine 773 by cysteine or histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes.

PubMed ID: 1609793

PubMed ID: 1424203

Title: Point mutations detected in the androgen receptor gene of three men with partial androgen insensitivity syndrome.

PubMed ID: 1424203

DOI: 10.1111/j.1365-2265.1992.tb02313.x

PubMed ID: 1426313

Title: A unique point mutation in the androgen receptor gene in a family with complete androgen insensitivity syndrome.

PubMed ID: 1426313

DOI: 10.1016/s0015-0282(16)55315-1

PubMed ID: 1487249

Title: Point mutation in the steroid-binding domain of the androgen receptor gene in a family with complete androgen insensitivity syndrome (CAIS).

PubMed ID: 1487249

DOI: 10.1007/bf00220088

PubMed ID: 1307250

Title: Androgen receptor gene mutations identified by SSCP in fourteen subjects with androgen insensitivity syndrome.

PubMed ID: 1307250

DOI: 10.1093/hmg/1.7.497

PubMed ID: 1569163

Title: A single amino acid substitution (Met-786-->Val) in the steroid-binding domain of human androgen receptor leads to complete androgen insensitivity syndrome.

PubMed ID: 1569163

DOI: 10.1210/jcem.74.5.1569163

PubMed ID: 1464650

Title: Immunoreactive androgen receptor expression in subjects with androgen resistance.

PubMed ID: 1464650

DOI: 10.1210/jcem.75.6.1464650

PubMed ID: 1430233

Title: Mutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene.

PubMed ID: 1430233

DOI: 10.1172/jci116093

PubMed ID: 1562539

Title: The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens.

PubMed ID: 1562539

DOI: 10.1016/0960-0760(92)90401-4

PubMed ID: 1316540

Title: Amino acid substitutions in the DNA-binding domain of the human androgen receptor are a frequent cause of receptor-binding positive androgen resistance.

PubMed ID: 1316540

DOI: 10.1210/mend.6.3.1316540

PubMed ID: 1480178

Title: Single base mutations in the human androgen receptor gene causing complete androgen insensitivity: rapid detection by a modified denaturing gradient gel electrophoresis technique.

PubMed ID: 1480178

DOI: 10.1210/mend.6.11.1480178

PubMed ID: 1303262

Title: A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.

PubMed ID: 1303262

DOI: 10.1038/ng1092-132

PubMed ID: 1631125

Title: Androgen receptor gene mutations in human prostate cancer.

PubMed ID: 1631125

DOI: 10.1073/pnas.89.14.6319

PubMed ID: 8213813

Title: Sequence variation in the androgen receptor gene is not a common determinant of male sexual orientation.

PubMed ID: 8213813

PubMed ID: 8224266

Title: A new mutation within the deoxyribonucleic acid-binding domain of the androgen receptor gene in a family with complete androgen insensitivity syndrome.

PubMed ID: 8224266

DOI: 10.1016/s0015-0282(16)56281-5

Sequence Information:

  • Length: 920
  • Mass: 99188
  • Checksum: A73432C55D39AE06
  • Sequence:
  • MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLLQQQ 
    QQQQQQQQQQ QQQQQQQQQQ ETSPRQQQQQ QGEDGSPQAH RRGPTGYLVL DEEQQPSQPQ 
    SALECHPERG CVPEPGAAVA ASKGLPQQLP APPDEDDSAA PSTLSLLGPT FPGLSSCSAD 
    LKDILSEAST MQLLQQQQQE AVSEGSSSGR AREASGAPTS SKDNYLGGTS TISDNAKELC 
    KAVSVSMGLG VEALEHLSPG EQLRGDCMYA PLLGVPPAVR PTPCAPLAEC KGSLLDDSAG 
    KSTEDTAEYS PFKGGYTKGL EGESLGCSGS AAAGSSGTLE LPSTLSLYKS GALDEAAAYQ 
    SRDYYNFPLA LAGPPPPPPP PHPHARIKLE NPLDYGSAWA AAAAQCRYGD LASLHGAGAA 
    GPGSGSPSAA ASSSWHTLFT AEEGQLYGPC GGGGGGGGGG GGGGGGGGGG GGGEAGAVAP 
    YGYTRPPQGL AGQESDFTAP DVWYPGGMVS RVPYPSPTCV KSEMGPWMDS YSGPYGDMRL 
    ETARDHVLPI DYYFPPQKTC LICGDEASGC HYGALTCGSC KVFFKRAAEG KQKYLCASRN 
    DCTIDKFRRK NCPSCRLRKC YEAGMTLGAR KLKKLGNLKL QEEGEASSTT SPTEETTQKL 
    TVSHIEGYEC QPIFLNVLEA IEPGVVCAGH DNNQPDSFAA LLSSLNELGE RQLVHVVKWA 
    KALPGFRNLH VDDQMAVIQY SWMGLMVFAM GWRSFTNVNS RMLYFAPDLV FNEYRMHKSR 
    MYSQCVRMRH LSQEFGWLQI TPQEFLCMKA LLLFSIIPVD GLKNQKFFDE LRMNYIKELD 
    RIIACKRKNP TSCSRRFYQL TKLLDSVQPI ARELHQFTFD LLIKSHMVSV DFPEMMAEII 
    SVQVPKILSG KVKPIYFHTQ

Genular Protein ID: 654034031

Symbol: A0A087WUX9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 572
  • Mass: 59436
  • Checksum: E4FDB1BF20D0178E
  • Sequence:
  • MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLLQQQ 
    QQQQQQQQQQ QQQQQQQQQQ ETSPRQQQQQ QGEDGSPQAH RRGPTGYLVL DEEQQPSQPQ 
    SALECHPERG CVPEPGAAVA ASKGLPQQLP APPDEDDSAA PSTLSLLGPT FPGLSSCSAD 
    LKDILSEAST MQLLQQQQQE AVSEGSSSGR AREASGAPTS SKDNYLGGTS TISDNAKELC 
    KAVSVSMGLG VEALEHLSPG EQLRGDCMYA PLLGVPPAVR PTPCAPLAEC KGSLLDDSAG 
    KSTEDTAEYS PFKGGYTKGL EGESLGCSGS AAAGSSGTLE LPSTLSLYKS GALDEAAAYQ 
    SRDYYNFPLA LAGPPPPPPP PHPHARIKLE NPLDYGSAWA AAAAQCRYGD LASLHGAGAA 
    GPGSGSPSAA ASSSWHTLFT AEEGQLYGPC GGGGGGGGGG GGGGGGGGGG GGGEAGAVAP 
    YGYTRPPQGL AGQESDFTAP DVWYPGGMVS RVPYPSPTCV KSEMGPWMDS YSGPYGDMRN 
    TRRKRLWKLI IRSINSCICS PRETEVPVRQ QK

Genular Protein ID: 1994014189

Symbol: Q9NUA2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12124798

Title: Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3.

PubMed ID: 12124798

DOI: 10.1002/ijc.10520

Sequence Information:

  • Length: 539
  • Mass: 55444
  • Checksum: AB493953B89D869F
  • Sequence:
  • MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLLQQQ 
    QQQQQQQQQQ QQQQQQQQQQ ETSPRQQQQQ QGEDGSPQAH RRGPTGYLVL DEEQQPSQPQ 
    SALECHPERG CVPEPGAAVA ASKGLPQQLP APPDEDDSAA PSTLSLLGPT FPGLSSCSAD 
    LKDILSEAST MQLLQQQQQE AVSEGSSSGR AREASGAPTS SKDNYLGGTS TISDNAKELC 
    KAVSVSMGLG VEALEHLSPG EQLRGDCMYA PLLGVPPAVR PTPCAPLAEC KGSLLDDSAG 
    KSTEDTAEYS PFKGGYTKGL EGESLGCSGS AAAGSSGTLE LPSTLSLYKS GALDEAAAYQ 
    SRDYYNFPLA LAGPPPPPPP PHPHARIKLE NPLDYGSAWA AAAAQCRYGD LASLHGAGAA 
    GPGSGSPSAA ASSSWHTLFT AEEGQLYGPC GGGGGGGGGG GGGGGGGGGG GGGEAGAVAP 
    YGYTRPPQGL AGQESDFTAP DVWYPGGMVS RVPYPSPTCV KSEMGPWMDS YSGPYGDMR

Genular Protein ID: 3500293997

Symbol: G4VV16_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 21878636

Title: Novel Membrane-associated Androgen Receptor Splice Variant Potentiates Proliferative and Survival Responses in Prostate Cancer Cells.

PubMed ID: 21878636

DOI: 10.1074/jbc.M111.265124

Sequence Information:

  • Length: 573
  • Mass: 59863
  • Checksum: 2A0FF3A289AC8975
  • Sequence:
  • MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP GASLLLQQQQ 
    QQQQQQQQQQ QQQQQQQQQQ QQQQQETSPR QQQQQQGEDG SPQAHRRGPT GYLVLDEEQQ 
    PSQPQSALEC HPERGCVPEP GAAVAASKGL PQQLPAPPDE DDSAAPSTLS LLGPTFPGLS 
    SCSADLKDIL SEASTMQLLQ QQQQEAVSEG SSSGRAREAS GAPTSSKDNY LGGTSTISDN 
    AKELCKAVSV SMGLGVEALE HLSPGEQLRG DCMYAPLLGV PPAVRPTPCA PLAECKGSLL 
    DDSAGKSTED TAEYSPFKGG YTKGLEGESL GCSGSAAAGS SGTLELPSTL SLYKSGALDE 
    AAAYQSRDYY NFPLALAGPP PPPPPPHPHA RIKLENPLDY GSAWAAAAAQ CRYGDLASLH 
    GAGAAGPGSG SPSAAASSSW HTLFTAEEGQ LYGPCGGGGG GGGGGGGGGG GGGGEAGAVA 
    PYGYTRPPQG LAGQESDFTA PDVWYPGGMV SRVPYPSPTC VKSEMGPWMD SYSGPYGDMR 
    NTRRKRLWKL IIRSINSCIC SPRETEVPVR QQK

Genular Protein ID: 2359757308

Symbol: F1D8N5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 388
  • Mass: 44643
  • Checksum: 495BAE974B4EFC75
  • Sequence:
  • MILWLHSLET ARDHVLPIDY YFPPQKTCLI CGDEASGCHY GALTCGSCKV FFKRAAEGKQ 
    KYLCASRNDC TIDKFRRKNC PSCRLRKCYE AGMTLGARKL KKLGNLKLQE EGEASSTTSP 
    TEETTQKLTV SHIEGYECQP IFLNVLEAIE PGVVCAGHDN NQPDSFAALL SSLNELGERQ 
    LVHVVKWAKA LPGFRNLHVD DQMAVIQYSW MGLMVFAMGW RSFTNVNSRM LYFAPDLVFN 
    EYRMHKSRMY SQCVRMRHLS QEFGWLQITP QEFLCMKALL LFSIIPVDGL KNQKFFDELR 
    MNYIKELDRI IACKRKNPTS CSRRFYQLTK LLDSVQPIAR ELHQFTFDLL IKSHMVSVDF 
    PEMMAEIISV QVPKILSGKV KPIYFHTQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.