Details for: ABCC6

Gene ID: 368

Symbol: ABCC6

Ensembl ID: ENSG00000091262

Description: ATP binding cassette subfamily C member 6

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.97
    Marker Score: 9718
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.52
    Marker Score: 9798
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.5
    Marker Score: 729
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.48
    Marker Score: 169269
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.45
    Marker Score: 6254
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.44
    Marker Score: 7731
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.27
    Marker Score: 2992
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.15
    Marker Score: 4096.5
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71814.5
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48039
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30407
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 503
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 457
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2411
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.95
    Marker Score: 1540
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5238
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2736
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.9
    Marker Score: 497
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 323
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5296
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.86
    Marker Score: 13888
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.81
    Marker Score: 618
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8
    Marker Score: 1993
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.78
    Marker Score: 6771
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.77
    Marker Score: 310
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.77
    Marker Score: 525
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 393
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.74
    Marker Score: 3091
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.73
    Marker Score: 1174
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.72
    Marker Score: 660
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.68
    Marker Score: 4448
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.67
    Marker Score: 2094.5
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.65
    Marker Score: 781
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.64
    Marker Score: 356
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.61
    Marker Score: 1162
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.61
    Marker Score: 406
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.59
    Marker Score: 634.5
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.57
    Marker Score: 367
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.56
    Marker Score: 1174
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 441
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.55
    Marker Score: 2871
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.54
    Marker Score: 920.5
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.54
    Marker Score: 158
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.54
    Marker Score: 173
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.53
    Marker Score: 250
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.52
    Marker Score: 127
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.5
    Marker Score: 224
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.48
    Marker Score: 1990
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.46
    Marker Score: 174
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.45
    Marker Score: 168
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.45
    Marker Score: 409
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.44
    Marker Score: 117
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.43
    Marker Score: 163
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.41
    Marker Score: 660
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.41
    Marker Score: 286
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.4
    Marker Score: 1378
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.4
    Marker Score: 121
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.39
    Marker Score: 458
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 368
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.36
    Marker Score: 132
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.36
    Marker Score: 351
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.35
    Marker Score: 1673
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.35
    Marker Score: 794
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.35
    Marker Score: 81
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.34
    Marker Score: 144
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.34
    Marker Score: 274
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.34
    Marker Score: 105
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.33
    Marker Score: 507
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.33
    Marker Score: 191
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.32
    Marker Score: 119
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.31
    Marker Score: 333
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.3
    Marker Score: 182
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.3
    Marker Score: 79
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 0.3
    Marker Score: 90
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.29
    Marker Score: 79
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.29
    Marker Score: 76
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.28
    Marker Score: 283.5
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.28
    Marker Score: 116
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.28
    Marker Score: 127
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.27
    Marker Score: 72
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.27
    Marker Score: 243
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.26
    Marker Score: 177
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.26
    Marker Score: 172.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.26
    Marker Score: 497
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.26
    Marker Score: 93
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.25
    Marker Score: 106
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.25
    Marker Score: 720
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 0.25
    Marker Score: 676
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.25
    Marker Score: 114
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.25
    Marker Score: 65
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.24
    Marker Score: 1006
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.24
    Marker Score: 252
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.24
    Marker Score: 666
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.23
    Marker Score: 558
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.23
    Marker Score: 668
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.23
    Marker Score: 401
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.23
    Marker Score: 327
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.23
    Marker Score: 92
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.23
    Marker Score: 59

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Other Information

## Summary ABCC6 is a member of the ATP-binding cassette subfamily C (ABC) of transporters, which are responsible for the transport of various molecules across cell membranes. This protein is expressed in a variety of cell types, including hepatocytes, endothelial cells, and immune cells. ## Key characteristics * ABCC6 is a multi-pass transmembrane protein with a molecular weight of approximately 145 kDa. * It is a member of the ABC family of transporters, which are involved in the transport of various molecules, including ions, proteins, and molecules. * ABCC6 is a key regulator of cellular phosphate homeostasis, and its dysfunction is associated with pxe, a genetic disorder characterized by impaired phosphate transport. * It is also involved in the regulation of calcium and magnesium ions. ## Pathways and functions * ABCC6 is involved in the transport of inorganic diphosphate (IPD) across cell membranes. * It is also involved in the transport of other molecules, such as proteins and ions. * ABCC6 is a key regulator of cellular phosphate homeostasis, and its dysfunction is associated with pxe. * It is also involved in the regulation of calcium and magnesium ions. ## Clinical significance * Mutations in the ABCC6 gene have been linked to pxe and other disorders that are characterized by impaired phosphate transport. * ABCC6 inhibitors are being investigated as potential treatments for these disorders. * The development of ABCC6 inhibitors could provide a new treatment for pxe and other related disorders.

Genular Protein ID: 4209153301

Symbol: MRP6_HUMAN

Name: ATP-binding cassette sub-family C member 6

UniProtKB Accession Codes:

O95255 A2RRN8 A8KIG6 A8Y988 E7ESW8 P78420 Q8TCY8 Q9UMZ7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 ChEBI 15 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 11 DrugCentral 1 EC 1 EMBL 9 Ensembl 4 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 4 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 2 Rhea 4 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10424734

Title: MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver.

PubMed ID: 10424734

DOI: 10.1038/sj.bjc.6690527

PubMed ID: 9892204

Title: Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells.

PubMed ID: 9892204

PubMed ID: 11431746

Title: A cellular gene up-regulated by hepatitis B virus-encoded X antigen promotes hepatocellular growth and survival.

PubMed ID: 11431746

DOI: 10.1053/jhep.2001.25545

PubMed ID: 21318057

Title: Identification of a new splice variant of the human ABCC6 transporter.

PubMed ID: 21318057

DOI: 10.1155/2008/912478

PubMed ID: 10493829

Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

PubMed ID: 10493829

DOI: 10.1006/geno.1999.5927

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12414644

Title: Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).

PubMed ID: 12414644

PubMed ID: 11880368

Title: Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6).

PubMed ID: 11880368

DOI: 10.1074/jbc.m110918200

PubMed ID: 11427982

Title: Molecular genetics of pseudoxanthoma elasticum: a metabolic disorder at the environment-genome interface?

PubMed ID: 11427982

DOI: 10.1016/s1471-4914(00)01869-4

PubMed ID: 12901863

Title: Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.

PubMed ID: 12901863

DOI: 10.1016/s0006-291x(03)01349-4

PubMed ID: 23625951

Title: ABCC6 is a basolateral plasma membrane protein.

PubMed ID: 23625951

DOI: 10.1161/circresaha.111.300194

PubMed ID: 23912081

Title: The hepatitis B x antigen anti-apoptotic effector URG7 is localized to the endoplasmic reticulum membrane.

PubMed ID: 23912081

DOI: 10.1016/j.febslet.2013.07.042

PubMed ID: 24277820

Title: ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release.

PubMed ID: 24277820

DOI: 10.1073/pnas.1319582110

PubMed ID: 24969777

Title: ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.

PubMed ID: 24969777

DOI: 10.1161/atvbaha.114.304017

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 35307651

Title: Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

PubMed ID: 35307651

DOI: 10.1124/dmd.121.000748

PubMed ID: 10913334

Title: Homozygosity for the R1268Q mutation in MRP6, the pseudoxanthoma elasticum gene, is not disease-causing.

PubMed ID: 10913334

DOI: 10.1006/bbrc.2000.3101

PubMed ID: 11058917

Title: Identification of two polymorphisms (c189G>C; c190T>C) in exon 2 of the human MRP6 gene (ABCC6) by screening of Pseudoxanthoma elasticum patients: possible sequence correction?

PubMed ID: 11058917

DOI: 10.1002/1098-1004(200011)16:5<449::aid-humu24>3.0.co;2-o

PubMed ID: 10954200

Title: Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum.

PubMed ID: 10954200

DOI: 10.1007/s001090000114

PubMed ID: 10835642

Title: Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum.

PubMed ID: 10835642

DOI: 10.1038/76102

PubMed ID: 10811882

Title: Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.

PubMed ID: 10811882

DOI: 10.1073/pnas.100041297

PubMed ID: 11536079

Title: A spectrum of ABCC6 mutations is responsible for pseudoxanthoma elasticum.

PubMed ID: 11536079

DOI: 10.1086/323704

PubMed ID: 11702217

Title: Identification of ABCC6 pseudogenes on human chromosome 16p: implications for mutation detection in pseudoxanthoma elasticum.

PubMed ID: 11702217

DOI: 10.1007/s004390100582

PubMed ID: 11776382

Title: ABCC6 gene polymorphism associated with variation in plasma lipoproteins.

PubMed ID: 11776382

DOI: 10.1007/s100380170003

PubMed ID: 15098239

Title: Does autosomal dominant pseudoxanthoma elasticum exist?

PubMed ID: 15098239

DOI: 10.1002/ajmg.a.20632

PubMed ID: 15459974

Title: ABCC6 mutations in Italian families affected by pseudoxanthoma elasticum (PXE).

PubMed ID: 15459974

DOI: 10.1002/humu.9284

PubMed ID: 15086542

Title: Novel ABCC6 mutations in pseudoxanthoma elasticum.

PubMed ID: 15086542

DOI: 10.1111/j.0022-202x.2004.22312.x

PubMed ID: 16086317

Title: Molecular genetics of pseudoxanthoma elasticum: type and frequency of mutations in ABCC6.

PubMed ID: 16086317

DOI: 10.1002/humu.20206

PubMed ID: 17617515

Title: Mutation detection in the ABCC6 gene and genotype-phenotype analysis in a large international case series affected by pseudoxanthoma elasticum.

PubMed ID: 17617515

DOI: 10.1136/jmg.2007.051094

PubMed ID: 18987736

Title: DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.

PubMed ID: 18987736

DOI: 10.1038/nature07485

PubMed ID: 19339160

Title: Spectrum of genetic variation at the ABCC6 locus in South Africans: Pseudoxanthoma elasticum patients and healthy individuals.

PubMed ID: 19339160

DOI: 10.1016/j.jdermsci.2009.02.008

PubMed ID: 20034067

Title: An unusual severe vascular case of pseudoxanthoma elasticum presenting as generalized arterial calcification of infancy.

PubMed ID: 20034067

DOI: 10.1002/ajmg.a.33162

PubMed ID: 22209248

Title: Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6.

PubMed ID: 22209248

DOI: 10.1016/j.ajhg.2011.11.020

PubMed ID: 25615550

Title: Genetic heterogeneity of pseudoxanthoma elasticum: the chinese signature profile of ABCC6 and ENPP1 mutations.

PubMed ID: 25615550

DOI: 10.1038/jid.2015.10

PubMed ID: 30154241

Title: Structural analysis reveals pathomechanisms associated with pseudoxanthoma elasticum-causing mutations in the ABCC6 transporter.

PubMed ID: 30154241

DOI: 10.1074/jbc.ra118.004806

Sequence Information:

  • Length: 1503
  • Mass: 164906
  • Checksum: 2107BE13B1547B39
  • Sequence:
    • MAAPAEPCAG QGVWNQTEPE PAATSLLSLC FLRTAGVWVP PMYLWVLGPI YLLFIHHHGR 
GYLRMSPLFK AKMVLGFALI VLCTSSVAVA LWKIQQGTPE APEFLIHPTV WLTTMSFAVF 
LIHTERKKGV QSSGVLFGYW LLCFVLPATN AAQQASGAGF QSDPVRHLST YLCLSLVVAQ 
FVLSCLADQP PFFPEDPQQS NPCPETGAAF PSKATFWWVS GLVWRGYRRP LRPKDLWSLG 
RENSSEELVS RLEKEWMRNR SAARRHNKAI AFKRKGGSGM KAPETEPFLR QEGSQWRPLL 
KAIWQVFHST FLLGTLSLII SDVFRFTVPK LLSLFLEFIG DPKPPAWKGY LLAVLMFLSA 
CLQTLFEQQN MYRLKVLQMR LRSAITGLVY RKVLALSSGS RKASAVGDVV NLVSVDVQRL 
TESVLYLNGL WLPLVWIVVC FVYLWQLLGP SALTAIAVFL SLLPLNFFIS KKRNHHQEEQ 
MRQKDSRARL TSSILRNSKT IKFHGWEGAF LDRVLGIRGQ ELGALRTSGL LFSVSLVSFQ 
VSTFLVALVV FAVHTLVAEN AMNAEKAFVT LTVLNILNKA QAFLPFSIHS LVQARVSFDR 
LVTFLCLEEV DPGVVDSSSS GSAAGKDCIT IHSATFAWSQ ESPPCLHRIN LTVPQGCLLA 
VVGPVGAGKS SLLSALLGEL SKVEGFVSIE GAVAYVPQEA WVQNTSVVEN VCFGQELDPP 
WLERVLEACA LQPDVDSFPE GIHTSIGEQG MNLSGGQKQR LSLARAVYRK AAVYLLDDPL 
AALDAHVGQH VFNQVIGPGG LLQGTTRILV THALHILPQA DWIIVLANGA IAEMGSYQEL 
LQRKGALMCL LDQARQPGDR GEGETEPGTS TKDPRGTSAG RRPELRRERS IKSVPEKDRT 
TSEAQTEVPL DDPDRAGWPA GKDSIQYGRV KATVHLAYLR AVGTPLCLYA LFLFLCQQVA 
SFCRGYWLSL WADDPAVGGQ QTQAALRGGI FGLLGCLQAI GLFASMAAVL LGGARASRLL 
FQRLLWDVVR SPISFFERTP IGHLLNRFSK ETDTVDVDIP DKLRSLLMYA FGLLEVSLVV 
AVATPLATVA ILPLFLLYAG FQSLYVVSSC QLRRLESASY SSVCSHMAET FQGSTVVRAF 
RTQAPFVAQN NARVDESQRI SFPRLVADRW LAANVELLGN GLVFAAATCA VLSKAHLSAG 
LVGFSVSAAL QVTQTLQWVV RNWTDLENSI VSVERMQDYA WTPKEAPWRL PTCAAQPPWP 
QGGQIEFRDF GLRYRPELPL AVQGVSFKIH AGEKVGIVGR TGAGKSSLAS GLLRLQEAAE 
GGIWIDGVPI AHVGLHTLRS RISIIPQDPI LFPGSLRMNL DLLQEHSDEA IWAALETVQL 
KALVASLPGQ LQYKCADRGE DLSVGQKQLL CLARALLRKT QILILDEATA AVDPGTELQM 
QAMLGSWFAQ CTVLLIAHRL RSVMDCARVL VMDKGQVAES GSPAQLLAQK GLFYRLAQES 
GLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.