Fen1 | FBgn0025832 | NCBI 36887

Details for: Fen1

Gene ID: 36887

Symbol: Fen1

Ensembl ID: FBgn0025832

Description: Flap endonuclease 1

Associated with

Base excision repair
(R-DME-73884)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Dna double-strand break repair
(R-DME-5693532)
Dna repair
(R-DME-73894)
Dna replication
(R-DME-69306)
Dna strand elongation
(R-DME-69190)
Hdr through mmej (alt-nhej)
(R-DME-5685939)
Homology directed repair
(R-DME-5693538)
Lagging strand synthesis
(R-DME-69186)
Pcna-dependent long patch base excision repair
(R-DME-5651801)
Processive synthesis on the lagging strand
(R-DME-69183)
Removal of the flap intermediate
(R-DME-69166)
Resolution of abasic sites (ap sites)
(R-DME-73933)
Resolution of ap sites via the multiple-nucleotide patch replacement pathway
(R-DME-110373)
S phase
(R-DME-69242)
Synthesis of dna
(R-DME-69239)
5'-3' exonuclease activity
(GO:0008409)
5'-flap endonuclease activity
(GO:0017108)
Catalytic activity
(GO:0003824)
Dna binding
(GO:0003677)
Endonuclease activity
(GO:0004519)
Hydrolase activity, acting on ester bonds
(GO:0016788)
Magnesium ion binding
(GO:0000287)
Manganese ion binding
(GO:0030145)
Nuclease activity
(GO:0004518)
Nucleus
(GO:0005634)
Rna-dna hybrid ribonuclease activity
(GO:0004523)

Other Information

Proteins

FEN1_DROME

Genular Protein ID: 1331852331

Symbol: FEN1_DROME

Name: N/A

UniProtKB Accession Codes:

Q7K7A9

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731137

Title: From sequence to chromosome: the tip of the X chromosome of D. melanogaster.

PubMed ID: 10731137

DOI: 10.1126/science.287.5461.2220

Sequence Information:

Length: 385
Mass: 42948
Checksum: D0A0831C2BDA9240
Sequence:

MGILGLSKLI ADLAPQAIRE SEMKHFFGRK VAIDASMCLY QFLIAVRSEG AQLATVNGDP 
TSHLMGMFYR TIRLLDNGIK PVYVFDGKPP DLKSGELAKR AERREEAEKA LKAATDAGDD 
AGIEKFNRRL VRVTKEHAKE AKELLTLMGV PYVDAPCEAE AQCAALVKAG KVYATATEDM 
DALTFGSTKL LRYLTYSEAR KMPVKEFSYD KLLEGLAINN REFIDLCILL GCDYCESIKG 
IGPKRAIELI NTYRDIETIL DNLDSSKYTV PENWNYKVAR ELFIEPEVAD ADSIDLKWVE 
PDEEGLVKFL CGDRQFNEER VRNGAKKLMK SKQAQTQVRL DSFFKTLPST PNATNAAKRK 
AEEAKKSANN KKAKTSGGGR GRRPK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.