Details for: Dark

Gene ID: 36914

Symbol: Dark

Ensembl ID: FBgn0263864

Description: Death-associated APAF1-related killer

Associated with

Other Information

Genular Protein ID: 3285635878

Symbol: Q7KLI1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10619022

Title: HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis.

PubMed ID: 10619022

DOI: 10.1016/S1097-2765(00)80385-8

PubMed ID: 10619023

Title: Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator.

PubMed ID: 10619023

DOI: 10.1016/S1097-2765(00)80386-X

PubMed ID: 10559939

Title: Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway.

PubMed ID: 10559939

DOI: 10.1038/12984

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 21220123

Title: Structure of the Drosophila apoptosome at 6.9a resolution.

PubMed ID: 21220123

DOI: 10.1016/j.str.2010.10.009

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25644603

Title: Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.

PubMed ID: 25644603

DOI: 10.1101/gad.255877.114

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

PubMed ID: 27916517

Title: A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation.

PubMed ID: 27916517

DOI: 10.1016/j.str.2016.11.002

PubMed ID: 38381783

Title: Dark and Dronc activation in <i>Drosophila melanogaster</i>.

PubMed ID: 38381783

DOI: 10.1073/pnas.2312784121

Sequence Information:

  • Length: 1440
  • Mass: 165619
  • Checksum: 74EFEAD06E54FA74
  • Sequence:
  • MDFETGEHQY QYKDILSVFE DAFVDNFDCK DVQDMPKSIL SKEEIDHIIM SKDAVSGTLR 
    LFWTLLSKQE EMVQKFVEEV LRINYKFLMS PIKTEQRQPS MMTRMYIEQR DRLYNDNQVF 
    AKYNVSRLQP YLKLRQALLE LRPAKNVLID GVLGSGKTWV ALDVCLSYKV QCKMDFKIFW 
    LNLKNCNSPE TVLEMLQKLL YQIDPNWTSR SDHSSNIKLR IHSIQAELRR LLKSKPYENC 
    LLVLLNVQNA KAWNAFNLSC KILLTTRFKQ VTDFLSAATT THISLDHHSM TLTPDEVKSL 
    LLKYLDCRPQ DLPREVLTTN PRRLSIIAES IRDGLATWDN WKHVNCDKLT TIIESSLNVL 
    EPAEYRKMFD RLSVFPPSAH IPTILLSLIW FDVIKSDVMV VVNKLHKYSL VEKQPKESTI 
    SIPSIYLELK VKLENEYALH RSIVDHYNIP KTFDSDDLIP PYLDQYFYSH IGHHLKNIEH 
    PERMTLFRMV FLDFRFLEQK IRHDSTAWNA SGSILNTLQQ LKFYKPYICD NDPKYERLVN 
    AILDFLPKIE ENLICSKYTD LLRIALMAED EAIFEEAHKQ VQRFDDRVWF TNHGRFHQHR 
    QIINLGDNEG RHAVYLHNDF CLIALASGQI LLTDVSLEGE DTYLLRDESD SSDILRMAVF 
    NQQKHLITLH CNGSVKLWSL WPDCPGRRHS GGSKQQLVNS VVKRFIGSYA NLKIVAFYLN 
    EDAGLPEANI QLHVAFINGD VSILNWDEQD QEFKLSHVPV LKTMQSGIRC FVQVLKRYYV 
    VCTSNCTLTV WDLTNGSSNT LELHVFNVEN DTPLALDVFD ERSKTATVLL IFKYSVWRLN 
    FLPGLSVSLQ SEAVQLPEGS FITCGKRSTD GRYLLLGTSE GLIVYDLKIS DPVLRSNVSE 
    HIECVDIYEL FDPVYKYIVL CGAKGKQVVH VHTLRSVSGS NSHQNREIAW VHSADEISVM 
    TKACLEPNVY LRSLMDMTRE RTQLLAVDSK ERIHLIKPAI SRISEWSTIT PTHAASNCKI 
    NAISAFNDEQ IFVGYVDGVI IDVIHDTALP QQFIEEPIDY LKQVSPNILV ASAHSAQKTV 
    IFQLEKIDPL QPNDQWPLMM DVSTKYASLQ EGQYIILFSD HGVCHLDIAN PSAFVKPKDS 
    EEYIVGFDLK NSLLFLAYEN NIIDVFRLIF SCNQLRYEQI CEEEIAQKAK ISYLVATDDG 
    TMLAMGFENG TLELFAVENR KVQLIYSIEE VHEHCIRQLL FSPCKLLLIS CAEQLCFWNV 
    THMRNNQLER EQKRRRSRRH KQHSVTQEDA VDAAPIAADI DVDVTFVADE FHPVNRGTAE 
    LWRNKRGNAI RPELLACVKF VGNEARQFFT DAHFSHFYAI DDEGVYYHLQ LLELSRLQPP 
    PDPVTLDIAN QYEDLKNLRI LDSPLMQDSD SEGADVVGNL VLEKNGGVAR ATPILEEASS

Genular Protein ID: 31161083

Symbol: Q9U8R4_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10619023

Title: Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator.

PubMed ID: 10619023

DOI: 10.1016/S1097-2765(00)80386-X

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 531
  • Mass: 62302
  • Checksum: FF25306B8F4007D2
  • Sequence:
  • MDFETGEHQY QYKDILSVFE DAFVDNFDCK DVQDMPKSIL SKEEIDHIIM SKDAVSGTLR 
    LFWTLLSKQE EMVQKFVEEV LRINYKFLMS PIKTEQRQPS MMTRMYIEQR DRLYNDNQVF 
    AKYNVSRLQP YLKLRQALLE LRPAKNVLID GVLGSGKTWV ALDVCLSYKV QCKMDFKIFW 
    LNLKNCNSPE TVLEMLQKLL YQIDPNWTSR SDHSSNIKLR IHSIQAELRR LLKSKPYENC 
    LLVLLNVQNA KAWNAFNLSC KILLTTRFKQ VTDFLSAATT THISLDHHSM TLTPDEVKSL 
    LLKYLDCRPQ DLPREVLTTN PRRLSIIAES IRDGLATWDN WKHVNCDKLT TIIESSLNVL 
    EPAEYRKMFD RLSVFPPSAH IPTILLSLIW FDVIKSDVMV VVNKLHKYSL VEKQPKESTI 
    SIPSIYLELK VKLENEYALH RSIVDHYNIP KTFDSDDLIP PYLDQYFYSH IGHHLKNIEH 
    PERMTLFRMV FLDFRFLEQK IRHDSTAWNA SGSILNTLQQ LKFYKPYICG T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.