Details for: ACADVL

Gene ID: 37

Symbol: ACADVL

Ensembl ID: ENSG00000072778

Description: acyl-CoA dehydrogenase very long chain

Associated with

Other Information

Genular Protein ID: 1016093399

Symbol: ACADV_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7668252

Title: Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients.

PubMed ID: 7668252

PubMed ID: 8845838

Title: Cloning and characterization of human very-long-chain acyl-CoA dehydrogenase cDNA, chromosomal assignment of the gene and identification in four patients of nine different mutations within the VLCAD gene.

PubMed ID: 8845838

DOI: 10.1093/hmg/5.4.461

PubMed ID: 8554625

Title: Genomic DNA organization of human mitochondrial very-long-chain acyl-CoA dehydrogenase and mutation analysis.

PubMed ID: 8554625

DOI: 10.1006/bbrc.1995.2867

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7769092

Title: Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients.

PubMed ID: 7769092

DOI: 10.1172/jci117947

PubMed ID: 9461620

Title: Catalytic and FAD-binding residues of mitochondrial very long chain acyl-coenzyme A dehydrogenase.

PubMed ID: 9461620

DOI: 10.1074/jbc.273.7.4227

PubMed ID: 9973285

Title: Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency.

PubMed ID: 9973285

DOI: 10.1086/302261

PubMed ID: 17374501

Title: Expression and characterization of mutations in human very long-chain acyl-CoA dehydrogenase using a prokaryotic system.

PubMed ID: 17374501

DOI: 10.1016/j.ymgme.2007.01.013

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21237683

Title: Identification and characterization of new long chain acyl-CoA dehydrogenases.

PubMed ID: 21237683

DOI: 10.1016/j.ymgme.2010.12.005

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 18227065

Title: Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.

PubMed ID: 18227065

DOI: 10.1074/jbc.m709135200

PubMed ID: 8554073

Title: Mutation analysis of very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) deficiency: identification and characterization of mutant VLCAD cDNAs from four patients.

PubMed ID: 8554073

PubMed ID: 9546340

Title: Very long chain acyl-coenzyme A dehydrogenase deficiency with adult onset.

PubMed ID: 9546340

DOI: 10.1002/ana.410430422

PubMed ID: 9839948

Title: Relationship between structure and substrate-chain-length specificity of mitochondrial very-long-chain acyl-coenzyme A dehydrogenase.

PubMed ID: 9839948

DOI: 10.1046/j.1432-1327.1998.2570592.x

PubMed ID: 9599005

Title: Very-long-chain acyl-CoA dehydrogenase subunit assembles to the dimer form on mitochondrial inner membrane.

PubMed ID: 9599005

DOI: 10.1016/s0014-5793(98)00343-3

PubMed ID: 10077518

Title: Molecular heterogeneity in very-long-chain acyl-CoA dehydrogenase deficiency causing pediatric cardiomyopathy and sudden death.

PubMed ID: 10077518

DOI: 10.1161/01.cir.99.10.1337

Sequence Information:

  • Length: 655
  • Mass: 70390
  • Checksum: A5594D1EA7911D19
  • Sequence:
  • MQAARMAASL GRQLLRLGGG SSRLTALLGQ PRPGPARRPY AGGAAQLALD KSDSHPSDAL 
    TRKKPAKAES KSFAVGMFKG QLTTDQVFPY PSVLNEEQTQ FLKELVEPVS RFFEEVNDPA 
    KNDALEMVEE TTWQGLKELG AFGLQVPSEL GGVGLCNTQY ARLVEIVGMH DLGVGITLGA 
    HQSIGFKGIL LFGTKAQKEK YLPKLASGET VAAFCLTEPS SGSDAASIRT SAVPSPCGKY 
    YTLNGSKLWI SNGGLADIFT VFAKTPVTDP ATGAVKEKIT AFVVERGFGG ITHGPPEKKM 
    GIKASNTAEV FFDGVRVPSE NVLGEVGSGF KVAMHILNNG RFGMAAALAG TMRGIIAKAV 
    DHATNRTQFG EKIHNFGLIQ EKLARMVMLQ YVTESMAYMV SANMDQGATD FQIEAAISKI 
    FGSEAAWKVT DECIQIMGGM GFMKEPGVER VLRDLRIFRI FEGTNDILRL FVALQGCMDK 
    GKELSGLGSA LKNPFGNAGL LLGEAGKQLR RRAGLGSGLS LSGLVHPELS RSGELAVRAL 
    EQFATVVEAK LIKHKKGIVN EQFLLQRLAD GAIDLYAMVV VLSRASRSLS EGHPTAQHEK 
    MLCDTWCIEA AARIREGMAA LQSDPWQQEL YRNFKSISKA LVERGGVVTS NPLGF

Genular Protein ID: 1807849729

Symbol: B3KPA6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 579
  • Mass: 62582
  • Checksum: F354E18C74751AE8
  • Sequence:
  • MFKGQLTTDQ VFPYPSVLNE EQTQFLKELV EPVSRFFEEV NDPAKNDALE MVEETTWQGL 
    KELGAFGLQV PSELGGVGLC NTQYARLVEI VGMHDLGVGI TLGAHQSIGF KGILLFGTKA 
    QKEKYLPKLA SGETVAAFCL TEPSSGSDAA SIRTSAVPSP CGKYYTLNGS KLWISNGGLA 
    DIFTVFAKTP VTDPATGAVK EKITAFVVER GFGGITHGPP EKKMGIKASN TAEVFFDGVR 
    VPSENVLGEV GSGFKVAMHI LNNGRFGMAA ALAGTMRGII AKAVDHATNR TQFGEKIHNF 
    GLIQEKLARM VMLQYVTESM AYMVSANMDQ GATDFQIEAA ISKIFGSEAA WKVTDECIQI 
    MGGMGFMKEP GVERVLRDLR IFRIFEGTND ILRLFVALQG CMDKGKELSG LGSALKNPFG 
    NAGLLLGEAG KQLRRRAGLG SGLSLSGLVH PELSRSGELA VRALEQFATV VEAKLIKHKK 
    GIVNEQFLLQ RLADGAIDLY AMVVVLSRAS RSLSEGHPTA QHEKMLCDTW CIEAAARIRE 
    GMAALQSDPW QQELYRNFKS ISKALVERGG VVTSNPLGF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.