Details for: eIF3c

Gene ID: 37005

Symbol: eIF3c

Ensembl ID: FBgn0034258

Description: eukaryotic translation initiation factor 3 subunit c

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-DME-72662)
  • Cap-dependent translation initiation
    (R-DME-72737)
  • Eukaryotic translation initiation
    (R-DME-72613)
  • Formation of a pool of free 40s subunits
    (R-DME-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-DME-72695)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-DME-156827)
  • Metabolism of proteins
    (R-DME-392499)
  • Ribosomal scanning and start codon recognition
    (R-DME-72702)
  • Translation
    (R-DME-72766)
  • Translation initiation complex formation
    (R-DME-72649)
  • Cytosol
    (GO:0005829)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Rna binding
    (GO:0003723)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)
  • Translation initiation factor binding
    (GO:0031369)

Other Information

Genular Protein ID: 3744238773

Symbol: EIF3C_DROME

Name: N/A

UniProtKB Accession Codes:

A1ZAX1 Q8MR49

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 9 GeneTree 1 Genevisible 1 GenomeRNAi 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 5 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 17392269

Title: The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation.

PubMed ID: 17392269

DOI: 10.1074/jbc.m701361200

PubMed ID: 17372656

Title: An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells.

PubMed ID: 17372656

DOI: 10.1039/b617545g

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 910
  • Mass: 105654
  • Checksum: FC05D6478712684A
  • Sequence:
    • MSRFFANGSE SESESSEEEI QATNFNKASA FQFSDDEEEV KRVVRSTKEK RYENLTSIIK 
TIRNHKKIKD IPNTLSSFED LTRAYQKALP VISKEENGIT PRFYIRCLAE LEDFINEVWE 
DREGRKNLSK NNSKSLGTLR QKVRKYIKDF EDDLSRFREA PDQESEAEDE VVALESDGGD 
AGDDSDAGVK PTEAVPKAVK SAPAKAAPAD DDDSDDSIDW DSDSESETES SDDENQYQNM 
RERFLKRTTE KEEKDDDKRK DKRKEQKTKI RKRAEDDEDG EWETVVKGHV VEKPKMFEKD 
AEIDVPLVLA KLLEIMSARG KKRTDRRLQI DLLFELRDIS DQHNLGTAVS VKIHFNIISA 
IYDYNQKISE PMKLEHWALL LEVMQSMMKL LLANADIIMS ESVAEEHEEY ATSPFYVRGC 
PLAAVERLDD EFVKLLKECD PHSNDYVSRL KDEVNVVKTI ELVLQYFERS GTNNERCRIY 
LRKIEHLYYK FDPEVLKKKR GELPATTSTS VDVMDKLCKF IYAKDDTDRI RTRAILAHIY 
HHAMHDNWFQ ARDLVLMSHL QDNIDAADPA TRILYNRMMA NLGLCAFRQG NVKDAHHCLV 
DLMVTGKPKE LLAQGLLPQR QHERSAEQEK IEKQRQMPFH MHINLELLEC VYLVSAMLLE 
IPYIAAHEFD ARRRMISKTF YQQLRSSERQ SLVGPPESMR EHVVAAAKAM RCGNWQACAN 
FIVNKKMNTK VWDLFYESDR VREMLTKFIK EESLRTYLFT YSNVYTSISI PSLAQMYELP 
VPKVHSIISK MIINEELMAS LDDPSETVGM HRSEPSRLQA LAMQFVDKVT NLVDVNEKVF 
DMKQGNFFQR GNMGNRGDRG YNRNQNNQGG NWLGQRRDRN NRNRNQRGHH KNNQDRQQQQ 
QQQVQTIDEE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.