PCNA | FBgn0005655 | NCBI 37290

Details for: PCNA

Gene ID: 37290

Symbol: PCNA

Ensembl ID: FBgn0005655

Description: Proliferating cell nuclear antigen

Associated with

Base excision repair
(R-DME-73884)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Dna damage bypass
(R-DME-73893)
Dna repair
(R-DME-73894)
Dna strand elongation
(R-DME-69190)
Dual incision in gg-ner
(R-DME-5696400)
Dual incision in tc-ner
(R-DME-6782135)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Global genome nucleotide excision repair (gg-ner)
(R-DME-5696399)
Lagging strand synthesis
(R-DME-69186)
Leading strand synthesis
(R-DME-69109)
Mismatch repair (mmr) directed by msh2:msh6 (mutsalpha)
(R-DME-5358565)
Nucleotide excision repair
(R-DME-5696398)
Pcna-dependent long patch base excision repair
(R-DME-5651801)
Polymerase switching
(R-DME-69091)
Processive synthesis on the lagging strand
(R-DME-69183)
Recognition of dna damage by pcna-containing replication complex
(R-DME-110314)
Removal of the flap intermediate
(R-DME-69166)
Resolution of abasic sites (ap sites)
(R-DME-73933)
Resolution of ap sites via the multiple-nucleotide patch replacement pathway
(R-DME-110373)
Rna polymerase ii transcription
(R-DME-73857)
S phase
(R-DME-69242)
Synthesis of dna
(R-DME-69239)
Termination of translesion dna synthesis
(R-DME-5656169)
Tp53 regulates transcription of cell cycle genes
(R-DME-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-DME-6804114)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-DME-6781827)
Transcriptional regulation by tp53
(R-DME-3700989)
Translesion synthesis by polh
(R-DME-110320)
Translesion synthesis by poli
(R-DME-5656121)
Translesion synthesis by polk
(R-DME-5655862)
Translesion synthesis by rev1
(R-DME-110312)
Translesion synthesis by y family dna polymerases bypasses lesions on dna template
(R-DME-110313)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Cytoplasm
(GO:0005737)
Dna-templated dna replication
(GO:0006261)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna polymerase processivity factor activity
(GO:0030337)
Dna replication
(GO:0006260)
Eggshell chorion gene amplification
(GO:0007307)
Leading strand elongation
(GO:0006272)
Mismatch repair
(GO:0006298)
Mitotic spindle organization
(GO:0007052)
Nuclear replication fork
(GO:0043596)
Nucleotide-excision repair
(GO:0006289)
Nucleus
(GO:0005634)
Pcna complex
(GO:0043626)
Regulation of dna replication
(GO:0006275)
Response to hydrogen peroxide
(GO:0042542)
Response to methyl methanesulfonate
(GO:0072702)
Response to uv
(GO:0009411)
Translesion synthesis
(GO:0019985)

Other Information

Proteins

PCNA_DROME

Genular Protein ID: 4275573884

Symbol: PCNA_DROME

Name: N/A

UniProtKB Accession Codes:

P17917 Q540V1 Q9V909

Database IDs:

Citations:

PubMed ID: 1968224

Title: Drosophila proliferating cell nuclear antigen (cyclin) gene: structure, expression during development, and specific binding of homeodomain proteins to its 5'-flanking region.

PubMed ID: 1968224

DOI: 10.1128/mcb.10.3.872-879.1990

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 1973166

Title: Drosophila proliferating cell nuclear antigen. Structural and functional homology with its mammalian counterpart.

PubMed ID: 1973166

DOI: 10.1016/s0021-9258(19)38492-3

PubMed ID: 1360647

Title: Delta-type DNA polymerase characterized from Drosophila melanogaster embryos.

PubMed ID: 1360647

DOI: 10.1093/nar/20.21.5779

PubMed ID: 7907981

Title: Mutagen sensitivity and suppression of position-effect variegation result from mutations in mus209, the Drosophila gene encoding PCNA.

PubMed ID: 7907981

DOI: 10.1002/j.1460-2075.1994.tb06399.x

PubMed ID: 9310333

Title: The cramped gene of Drosophila is a member of the polycomb-group, and interacts with mus209, the gene encoding proliferating cell nuclear antigen.

PubMed ID: 9310333

DOI: 10.1242/dev.124.17.3385

PubMed ID: 17087725

Title: Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.

PubMed ID: 17087725

DOI: 10.1111/j.1742-4658.2006.05504.x

PubMed ID: 19081076

Title: Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase.

PubMed ID: 19081076

DOI: 10.1016/j.devcel.2008.10.003

Sequence Information:

Length: 260
Mass: 28830
Checksum: 9A46280EA2C61FC5
Sequence:

MFEARLGQAT ILKKILDAIK DLLNEATFDC SDSGIQLQAM DNSHVSLVSL TLRSDGFDKF 
RCDRNLSMGM NLGSMAKILK CANNEDNVTM KAQDNADTVT IMFESANQEK VSDYEMKLMN 
LDQEHLGIPE TDFSCVVRMP AMEFARICRD LAQFSESVVI CCTKEGVKFS ASGDVGTANI 
KLAQTGSVDK EEEAVIIEMQ EPVTLTFACR YLNAFTKATP LSTQVQLSMC ADVPLVVEYA 
IKDLGHIRYY LAPKIEDNET

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PCNA

Associated with

Other Information

Drosophila proliferating cell nuclear antigen (cyclin) gene: structure, expression during development, and specific binding of homeodomain proteins to its 5'-flanking region. PubMed ID: 1968224

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Drosophila proliferating cell nuclear antigen. Structural and functional homology with its mammalian counterpart. PubMed ID: 1973166

Delta-type DNA polymerase characterized from Drosophila melanogaster embryos. PubMed ID: 1360647

Mutagen sensitivity and suppression of position-effect variegation result from mutations in mus209, the Drosophila gene encoding PCNA. PubMed ID: 7907981

The cramped gene of Drosophila is a member of the polycomb-group, and interacts with mus209, the gene encoding proliferating cell nuclear antigen. PubMed ID: 9310333

Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. PubMed ID: 17087725

Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase. PubMed ID: 19081076