Details for: TRIM23

Gene ID: 373

Symbol: TRIM23

Ensembl ID: ENSG00000113595

Description: tripartite motif containing 23

Associated with

Other Information

Genular Protein ID: 2813304776

Symbol: TRI23_HUMAN

Name: E3 ubiquitin-protein ligase TRIM23

UniProtKB Accession Codes:

P36406 Q9BZY4 Q9BZY5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CORUM 1 CTD 1 ChEBI 3 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 5 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 18 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 4 SIGNOR 1 SMART 6 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8473324

Title: ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl-terminal ADP-ribosylation factor domain.

PubMed ID: 8473324

DOI: 10.1016/s0021-9258(18)52945-8

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9671726

Title: Localization of ADP-ribosylation factor domain protein 1 (ARD1) in lysosomes and Golgi apparatus.

PubMed ID: 9671726

DOI: 10.1073/pnas.95.15.8613

PubMed ID: 10748148

Title: Specific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1).

PubMed ID: 10748148

DOI: 10.1074/jbc.m909642199

PubMed ID: 15684077

Title: E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1).

PubMed ID: 15684077

DOI: 10.1073/pnas.0409800102

PubMed ID: 19176615

Title: Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus.

PubMed ID: 19176615

DOI: 10.1128/jvi.02072-08

PubMed ID: 28871090

Title: TRIM23 mediates virus-induced autophagy via activation of TBK1.

PubMed ID: 28871090

DOI: 10.1038/s41564-017-0017-2

PubMed ID: 28681414

Title: Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.

PubMed ID: 28681414

DOI: 10.1002/prot.25348

Sequence Information:

  • Length: 574
  • Mass: 64067
  • Checksum: CB85923B29BF0320
  • Sequence:
    • MATLVVNKLG AGVDSGRQGS RGTAVVKVLE CGVCEDVFSL QGDKVPRLLL CGHTVCHDCL 
TRLPLHGRAI RCPFDRQVTD LGDSGVWGLK KNFALLELLE RLQNGPIGQY GAAEESIGIS 
GESIIRCDED EAHLASVYCT VCATHLCSEC SQVTHSTKTL AKHRRVPLAD KPHEKTMCSQ 
HQVHAIEFVC LEEGCQTSPL MCCVCKEYGK HQGHKHSVLE PEANQIRASI LDMAHCIRTF 
TEEISDYSRK LVGIVQHIEG GEQIVEDGIG MAHTEHVPGT AENARSCIRA YFYDLHETLC 
RQEEMALSVV DAHVREKLIW LRQQQEDMTI LLSEVSAACL HCEKTLQQDD CRVVLAKQEI 
TRLLETLQKQ QQQFTEVADH IQLDASIPVT FTKDNRVHIG PKMEIRVVTL GLDGAGKTTI 
LFKLKQDEFM QPIPTIGFNV ETVEYKNLKF TIWDVGGKHK LRPLWKHYYL NTQAVVFVVD 
SSHRDRISEA HSELAKLLTE KELRDALLLI FANKQDVAGA LSVEEITELL SLHKLCCGRS 
WYIQGCDARS GMGLYEGLDW LSRQLVAAGV LDVA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.