Details for: sktl

Gene ID: 37356

Symbol: sktl

Ensembl ID: FBgn0016984

Description: skittles

Associated with

Other Information

Genular Protein ID: 365006841

Symbol: PI5K1_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9832529

Title: skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release.

PubMed ID: 9832529

DOI: 10.1093/genetics/150.4.1527

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 27747405

Title: Expression of the PI4P 5-kinase Drosophila homologue skittles in the germline suggests a role in spermatogenesis and oogenesis.

PubMed ID: 27747405

DOI: 10.1007/s004270050099

PubMed ID: 15280236

Title: The direct interaction between ASH2, a Drosophila trithorax group protein, and SKTL, a nuclear phosphatidylinositol 4-phosphate 5-kinase, implies a role for phosphatidylinositol 4,5-bisphosphate in maintaining transcriptionally active chromatin.

PubMed ID: 15280236

DOI: 10.1534/genetics.103.018721

PubMed ID: 18948416

Title: PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.

PubMed ID: 18948416

DOI: 10.1242/dev.029009

PubMed ID: 20237161

Title: Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila.

PubMed ID: 20237161

DOI: 10.1091/mbc.e09-07-0582

PubMed ID: 23853710

Title: Apical targeting of the formin Diaphanous in Drosophila tubular epithelia.

PubMed ID: 23853710

DOI: 10.7554/elife.00666

PubMed ID: 24768049

Title: PI(4,5)P2 produced by the PI4P5K SKTL controls apical size by tethering PAR-3 in Drosophila epithelial cells.

PubMed ID: 24768049

DOI: 10.1016/j.cub.2014.03.056

PubMed ID: 31704968

Title: Interplay between integrins and PI4P5K Sktl is crucial for cell polarization and reepithelialisation during Drosophila wound healing.

PubMed ID: 31704968

DOI: 10.1038/s41598-019-52743-z

PubMed ID: 35437696

Title: PI(4,5)P2 controls slit diaphragm formation and endocytosis in Drosophila nephrocytes.

PubMed ID: 35437696

DOI: 10.1007/s00018-022-04273-7

Sequence Information:

  • Length: 792
  • Mass: 87758
  • Checksum: 45F7584FA2B008A4
  • Sequence:
  • MDTRVELELE PVGKQDRLKD QPDDENEPLE NQLELEQEHK SLLTPVKIPP AQTASPDQEA 
    TPSTPPPMSL QPGTSRQLFR DAAMAHGGQE TTSLLQQELN NIAATQTPAS KLRSASSTLD 
    ASISRNPSTT GGKHEKKLGH RRVAEGGEVT YKKIQSKQIM GSIQLGIQHT VGSLASKPKR 
    DLLMNDFWEM ETISFPPDGS SITPAHHYND FRFKVYAPIA FRYFRDLFGI APDDFLMSMC 
    ASPLRELSNP GASGSIFYLT TDDEFIIKTV QKKECEFLQK LLPGYYMNLS QNPRTLLPKF 
    FGLYCFHYNS KNVRLVAMNN LLPSDIKMHC KYDLKGSSFR RKASKAERQK ASPTFKDLDF 
    AEHHPNGIFL ETDKYNALMS TIKRDCMVLE SFQIMDYSLL VGIHNLDLAA KEKREERILN 
    ARAKLQRKES AAQGPPSLNP DDDAPEADQN QLQAVASYAS IPGTSAGAAL NRTRSMNRQR 
    LVAHSTALES ITADMDVPLE EDEDVPAGGI PARSENDERL ILYIGIIDIL QSYRLEKKLE 
    HTFKSILYNG DTVSVCRPSF YAKRFQDAMG KQVFKKTPTF PLKHSPSKRK TSTTQLRSPA 
    SRLPPLSTPT NAVRQPIMTM SGMSTPPPAF DDISEEDITA ASTSSLQQQR SSNQSNNNRG 
    ETEVALREGN NTRGGSGEPS STYHTQYSYD SSGRTGSALT SDYSDDESTG TDLSSRLPKL 
    RTHRLTKTSV QVTTVGYVEG VDTPPKGGQD VVHADVNGKT TMTTTTMLTT TKTAHIQAPS 
    YTSTLVLNDL PR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.