Details for: Tbp

Gene ID: 37476

Symbol: Tbp

Ensembl ID: FBgn0003687

Description: TATA binding protein

Associated with

  • Esr-mediated signaling
    (R-DME-8939211)
  • Estrogen-dependent gene expression
    (R-DME-9018519)
  • Gene expression (transcription)
    (R-DME-74160)
  • Generic transcription pathway
    (R-DME-212436)
  • Regulation of tp53 activity
    (R-DME-5633007)
  • Regulation of tp53 activity through phosphorylation
    (R-DME-6804756)
  • Rna polymerase iii transcription
    (R-DME-74158)
  • Rna polymerase iii transcription initiation
    (R-DME-76046)
  • Rna polymerase iii transcription initiation from type 1 promoter
    (R-DME-76061)
  • Rna polymerase iii transcription initiation from type 2 promoter
    (R-DME-76066)
  • Rna polymerase ii pre-transcription events
    (R-DME-674695)
  • Rna polymerase ii promoter escape
    (R-DME-73776)
  • Rna polymerase ii transcribes snrna genes
    (R-DME-6807505)
  • Rna polymerase ii transcription
    (R-DME-73857)
  • Rna polymerase ii transcription initiation
    (R-DME-75953)
  • Rna polymerase ii transcription initiation and promoter clearance
    (R-DME-76042)
  • Rna polymerase ii transcription pre-initiation and promoter opening
    (R-DME-73779)
  • Rna polymerase i promoter clearance
    (R-DME-73854)
  • Rna polymerase i promoter escape
    (R-DME-73772)
  • Rna polymerase i transcription
    (R-DME-73864)
  • Signaling by nuclear receptors
    (R-DME-9006931)
  • Signal transduction
    (R-DME-162582)
  • Transcriptional regulation by tp53
    (R-DME-3700989)
  • Dna-templated transcription initiation
    (GO:0006352)
  • Dna binding
    (GO:0003677)
  • General transcription initiation factor binding
    (GO:0140296)
  • Mrna transcription by rna polymerase ii
    (GO:0042789)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii general transcription initiation factor activity
    (GO:0016251)
  • Rna polymerase ii general transcription initiation factor binding
    (GO:0001091)
  • Rna polymerase iii general transcription initiation factor activity
    (GO:0000995)
  • Rna polymerase iii type 3 promoter sequence-specific dna binding
    (GO:0001006)
  • Rna polymerase ii preinitiation complex assembly
    (GO:0051123)
  • Snrna transcription by rna polymerase ii
    (GO:0042795)
  • Snrna transcription by rna polymerase iii
    (GO:0042796)
  • Tfiia-class transcription factor complex binding
    (GO:0001092)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription by rna polymerase iii
    (GO:0006383)
  • Transcription cis-regulatory region binding
    (GO:0000976)
  • Transcription factor tfiid complex
    (GO:0005669)
  • Transcription factor tfiiib complex
    (GO:0000126)
  • Transcription initiation at rna polymerase ii promoter
    (GO:0006367)
  • Trna transcription by rna polymerase iii
    (GO:0042797)

Other Information

Genular Protein ID: 3684637639

Symbol: TBP_DROME

Name: TATA-box-binding protein

UniProtKB Accession Codes:

P20227 Q9W2D8

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 6 EnsemblMetazoa 1 FlyBase 1 GO 20 Gene3D 1 GeneTree 1 GenomeRNAi 1 HAMAP 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 11 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 2194666

Title: Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID.

PubMed ID: 2194666

DOI: 10.1016/0092-8674(90)90682-5

PubMed ID: 2123550

Title: cDNA clone encoding Drosophila transcription factor TFIID.

PubMed ID: 2123550

DOI: 10.1073/pnas.87.23.9148

PubMed ID: 7875589

Title: Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster.

PubMed ID: 7875589

DOI: 10.1016/0378-1119(94)00764-j

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 8224849

Title: Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

PubMed ID: 8224849

DOI: 10.1101/gad.7.11.2235

PubMed ID: 8276241

Title: Molecular cloning and characterization of dTAFII30 alpha and dTAFII30 beta: two small subunits of Drosophila TFIID.

PubMed ID: 8276241

DOI: 10.1101/gad.7.12b.2587

PubMed ID: 8247000

Title: Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit.

PubMed ID: 8247000

DOI: 10.1128/mcb.13.12.7859-7863.1993

PubMed ID: 8464492

Title: Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator.

PubMed ID: 8464492

DOI: 10.1038/362511a0

PubMed ID: 8178153

Title: Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA.

PubMed ID: 8178153

DOI: 10.1126/science.8178153

Sequence Information:

  • Length: 353
  • Mass: 38451
  • Checksum: 7B079BC01BAF69BC
  • Sequence:
    • MDQMLSPNFS IPSIGTPLHQ MEADQQIVAN PVYHPPAVSQ PDSLMPAPGS SSVQHQQQQQ 
QSDASGGSGL FGHEPSLPLA HKQMQSYQPS ASYQQQQQQQ QLQSQAPGGG GSTPQSMMQP 
QTPQSMMAHM MPMSERSVGG SGAGGGGDAL SNIHQTMGPS TPMTPATPGS ADPGIVPQLQ 
NIVSTVNLCC KLDLKKIALH ARNAEYNPKR FAAVIMRIRE PRTTALIFSS GKMVCTGAKS 
EDDSRLAARK YARIIQKLGF PAKFLDFKIQ NMVGSCDVKF PIRLEGLVLT HCNFSSYEPE 
LFPGLIYRMV RPRIVLLIFV SGKVVLTGAK VRQEIYDAFD KIFPILKKFK KQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.