Details for: ARF1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.52
Marker Score: 119,724 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 3.3
Marker Score: 10,412 - Cell Name: blood cell (CL0000081)
Fold Change: 3.24
Marker Score: 37,627 - Cell Name: mature T cell (CL0002419)
Fold Change: 3.14
Marker Score: 31,106 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 3.13
Marker Score: 4,536 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 3.13
Marker Score: 8,640 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.13
Marker Score: 41,250 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 3.06
Marker Score: 171,124 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 2.97
Marker Score: 19,341 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 2.93
Marker Score: 7,451 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 2.89
Marker Score: 8,439 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 2.89
Marker Score: 2,571 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 2.83
Marker Score: 12,136 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 2.83
Marker Score: 2,483 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 2.82
Marker Score: 149,023 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 2.82
Marker Score: 2,722 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.8
Marker Score: 6,843 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.77
Marker Score: 2,955 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.76
Marker Score: 660 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.75
Marker Score: 2,342 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.73
Marker Score: 10,540 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 2.69
Marker Score: 1,126 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 2.67
Marker Score: 2,631 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.67
Marker Score: 7,492 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.67
Marker Score: 1,111 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 2.66
Marker Score: 3,924 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.65
Marker Score: 2,077 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 2.65
Marker Score: 17,245 - Cell Name: epithelial cell (CL0000066)
Fold Change: 2.65
Marker Score: 4,208 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 2.64
Marker Score: 6,450 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 2.64
Marker Score: 5,142 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.63
Marker Score: 2,827 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.63
Marker Score: 11,328 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.63
Marker Score: 8,243 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 2.62
Marker Score: 3,612 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 2.6
Marker Score: 1,516 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.6
Marker Score: 2,189 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 2.6
Marker Score: 1,524 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 2.6
Marker Score: 2,129 - Cell Name: stromal cell (CL0000499)
Fold Change: 2.58
Marker Score: 3,026 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.58
Marker Score: 4,149 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.58
Marker Score: 2,803 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 2.57
Marker Score: 2,410 - Cell Name: acinar cell (CL0000622)
Fold Change: 2.57
Marker Score: 1,811 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 2.55
Marker Score: 19,910 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.54
Marker Score: 16,244 - Cell Name: platelet (CL0000233)
Fold Change: 2.52
Marker Score: 1,142 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 2.52
Marker Score: 16,063 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 2.51
Marker Score: 4,491 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.5
Marker Score: 2,865 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 2.5
Marker Score: 13,130 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 2.49
Marker Score: 10,397 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 2.49
Marker Score: 1,421 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 2.48
Marker Score: 2,381 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 2.48
Marker Score: 1,957 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 2.48
Marker Score: 2,930 - Cell Name: Unknown (CL0000548)
Fold Change: 2.48
Marker Score: 1,805 - Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.47
Marker Score: 1,125 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.47
Marker Score: 2,214 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 2.46
Marker Score: 5,157 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.46
Marker Score: 4,620 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 2.45
Marker Score: 1,475 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 2.45
Marker Score: 1,646 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 2.44
Marker Score: 3,017 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.44
Marker Score: 84,650 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.44
Marker Score: 4,008 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 2.44
Marker Score: 1,661 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.44
Marker Score: 4,126 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.43
Marker Score: 20,978 - Cell Name: pro-B cell (CL0000826)
Fold Change: 2.43
Marker Score: 2,349 - Cell Name: malignant cell (CL0001064)
Fold Change: 2.43
Marker Score: 32,620 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 2.43
Marker Score: 3,434 - Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 2.43
Marker Score: 11,913 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.41
Marker Score: 27,200 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 2.4
Marker Score: 6,542 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.4
Marker Score: 4,249 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.39
Marker Score: 4,771 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.38
Marker Score: 5,432 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 2.38
Marker Score: 1,026 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 2.38
Marker Score: 2,024 - Cell Name: adventitial cell (CL0002503)
Fold Change: 2.37
Marker Score: 586 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 2.37
Marker Score: 4,649 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 2.37
Marker Score: 2,230 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 2.37
Marker Score: 628 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 2.37
Marker Score: 2,235 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.36
Marker Score: 23,949 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 2.36
Marker Score: 1,216 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.36
Marker Score: 4,927 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 2.34
Marker Score: 810 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 2.34
Marker Score: 582 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.34
Marker Score: 6,118 - Cell Name: enterocyte (CL0000584)
Fold Change: 2.33
Marker Score: 11,196 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.33
Marker Score: 1,535 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.33
Marker Score: 5,490 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 2.33
Marker Score: 1,546 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 2.32
Marker Score: 6,219 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.32
Marker Score: 1,040 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 2.32
Marker Score: 582 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.31
Marker Score: 2,596 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 2.31
Marker Score: 3,560
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 125910785
Symbol: ARF1_HUMAN
Name: ADP-ribosylation factor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2474826
Title: Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin.
PubMed ID: 2474826
PubMed ID: 1899243
Title: Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins.
PubMed ID: 1899243
PubMed ID: 1577740
Title: Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.
PubMed ID: 1577740
PubMed ID: 9110174
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8253837
Title: Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.
PubMed ID: 8253837
PubMed ID: 8861955
Title: p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.
PubMed ID: 8861955
PubMed ID: 10022920
Title: Identification of a new Pyk2 target protein with Arf-GAP activity.
PubMed ID: 10022920
PubMed ID: 11950392
Title: GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.
PubMed ID: 11950392
DOI: 10.1042/bj20020428
PubMed ID: 15107860
Title: FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P.
PubMed ID: 15107860
DOI: 10.1038/ncb1119
PubMed ID: 17347647
Title: Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes.
PubMed ID: 17347647
PubMed ID: 17555535
Title: Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta.
PubMed ID: 17555535
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20213681
Title: Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system.
PubMed ID: 20213681
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21454700
Title: Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.
PubMed ID: 21454700
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23535599
Title: Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ.
PubMed ID: 23535599
DOI: 10.1038/nature12004
PubMed ID: 23889934
Title: The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity.
PubMed ID: 23889934
PubMed ID: 24058294
Title: Integrated conformational and lipid-sensing regulation of endosomal ArfGEF BRAG2.
PubMed ID: 24058294
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25255805
Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
PubMed ID: 25255805
DOI: 10.1038/ncomms5919
PubMed ID: 25807930
Title: Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development.
PubMed ID: 25807930
PubMed ID: 28868155
Title: Missense-depleted regions in population exomes implicate ras superfamily nucleotide-binding protein alteration in patients with brain malformation.
PubMed ID: 28868155
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 7990966
Title: Structure of the human ADP-ribosylation factor 1 complexed with GDP.
PubMed ID: 7990966
DOI: 10.1038/372704a0
PubMed ID: 10102276
Title: Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis.
PubMed ID: 10102276
PubMed ID: 14690595
Title: Crystal structure of ARF1*Sec7 complexed with brefeldin A and its implications for the guanine nucleotide exchange mechanism.
PubMed ID: 14690595
PubMed ID: 15308674
Title: Conformational changes in human Arf1 on nucleotide exchange and deletion of membrane-binding elements.
PubMed ID: 15308674
Sequence Information:
- Length: 181
- Mass: 20697
- Checksum: AAC773D4A60186B6
- Sequence:
MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKLGLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.