CycB | FBgn0000405 | NCBI 37618

Details for: CycB

Gene ID: 37618

Symbol: CycB

Ensembl ID: FBgn0000405

Description: Cyclin B

Associated with

Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-DME-176814)
Apc/c-mediated degradation of cell cycle proteins
(R-DME-174143)
Apc/c:cdc20 mediated degradation of cyclin b
(R-DME-174048)
Apc/c:cdc20 mediated degradation of mitotic proteins
(R-DME-176409)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Cell cycle checkpoints
(R-DME-69620)
Chk1/chk2(cds1) mediated inactivation of cyclin b:cdk1 complex
(R-DME-75035)
Cyclin a/b1/b2 associated events during g2/m transition
(R-DME-69273)
Depolymerization of the nuclear lamina
(R-DME-4419969)
G2/m checkpoints
(R-DME-69481)
G2/m dna damage checkpoint
(R-DME-69473)
G2/m dna replication checkpoint
(R-DME-69478)
G2/m transition
(R-DME-69275)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Mitotic g2-g2/m phases
(R-DME-453274)
Mitotic prometaphase
(R-DME-68877)
Mitotic prophase
(R-DME-68875)
M phase
(R-DME-68886)
Nuclear envelope breakdown
(R-DME-2980766)
Nuclear pore complex (npc) disassembly
(R-DME-3301854)
Phosphorylation of emi1
(R-DME-176417)
Phosphorylation of the apc/c
(R-DME-176412)
Regulation of apc/c activators between g1/s and early anaphase
(R-DME-176408)
Regulation of mitotic cell cycle
(R-DME-453276)
Regulation of plk1 activity at g2/m transition
(R-DME-2565942)
Resolution of sister chromatid cohesion
(R-DME-2500257)
Rna polymerase ii transcription
(R-DME-73857)
Tp53 regulates transcription of cell cycle genes
(R-DME-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-DME-6804114)
Transcriptional regulation by runx2
(R-DME-8878166)
Transcriptional regulation by tp53
(R-DME-3700989)
Attachment of spindle microtubules to kinetochore
(GO:0008608)
Centrosome
(GO:0005813)
Chromosome, centromeric region
(GO:0000775)
Cyclin-dependent protein kinase holoenzyme complex
(GO:0000307)
Cyclin-dependent protein serine/threonine kinase regulator activity
(GO:0016538)
Cytoplasm
(GO:0005737)
Embryonic development via the syncytial blastoderm
(GO:0001700)
G2/m transition of mitotic cell cycle
(GO:0000086)
Germ-line cyst formation
(GO:0048134)
Midbody abscission
(GO:0061952)
Mitotic cell cycle phase transition
(GO:0044772)
Mitotic chromosome movement towards spindle pole
(GO:0007079)
Mitotic cytokinesis
(GO:0000281)
Mitotic spindle
(GO:0072686)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of chromatin binding
(GO:0035561)
Regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0000079)
Spindle midzone
(GO:0051233)
Syncytial blastoderm mitotic cell cycle
(GO:0035186)

Other Information

Proteins

G2/mitotic-specific cyclin-B
C9QPI9_DROME

Genular Protein ID: 2157397331

Symbol: CCNB_DROME

Name: G2/mitotic-specific cyclin-B

UniProtKB Accession Codes:

P20439 Q0E8Y2 Q8MME2 Q9I7V2 Q9TYH6 Q9TYH7 Q9V3F4

Database IDs:

Citations:

PubMed ID: 2139805

Title: The roles of Drosophila cyclins A and B in mitotic control.

PubMed ID: 2139805

DOI: 10.1016/0092-8674(90)90535-m

PubMed ID: 2142452

Title: The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition.

PubMed ID: 2142452

DOI: 10.1002/j.1460-2075.1990.tb07437.x

PubMed ID: 1451670

Title: 3' non-translated sequences in Drosophila cyclin B transcripts direct posterior pole accumulation late in oogenesis and peri-nuclear association in syncytial embryos.

PubMed ID: 1451670

DOI: 10.1242/dev.115.4.989

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 2564167

Title: Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis.

PubMed ID: 2564167

DOI: 10.1038/338337a0

PubMed ID: 17372656

Title: An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells.

PubMed ID: 17372656

DOI: 10.1039/b617545g

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

Length: 530
Mass: 59256
Checksum: D74ABEE0C8066D4A
Sequence:

MVGTTLKMRG DENASENFKQ VQLKKLTVPS MEATTKRAAL GDLQNRGISR PIAAKDAAQK 
DSKDLKLTDA LRNAKARVDS HWKKQPLGST NGNGNGAVPP KVNEGGVSAF LRSNSVRNRV 
PTKTTVEPTK VTVKSSSSEN VNEPTLKRED SNLSKKSLTK LRAALAKPVM GVSGIRREPV 
AVSRKEAETK KELPETKKDS LEVKKDATRM PLIRGNSAVT TTTSTMPTTM SLSSKRLAGI 
EDIDANDKEN LVLVSEYVND IYDYLYQVEL EQPIHKDHLA GQKEVSHKMR AVLIDWINEV 
HLQFHLAAET FQLAVAIIDR YLQVVKDTKR TYLQLVGVTA LFIATKYEEL FPPAIGDFVF 
ITDDTYTARQ IRQMELQIFK AIDCNLSRPL PIHFLRRYSK AAGAEDEHHT MSKYFIELAS 
VDYEMATYRP SEIAAASLFL SLHLLNGNHR AGTGFNDRHW TPTLTFYSRY SAAHLRPITR 
LIAKLARDAP QAKLKAIYNK YQGSKFQKIA LRTELTGALM DSIVGQSQRK

Genular Protein ID: 1529218964

Symbol: C9QPI9_DROME

Name: N/A

UniProtKB Accession Codes:

C9QPI9

Database IDs:

Sequence Information:

Length: 524
Mass: 58580
Checksum: ECFAD5B6DCCF5D0E
Sequence:

MAALEKNASE NFKQVQLKKL TVPSMEATTK RAALGDLQNR GISRPIAAKD AAQKDSKDLK 
LTDALRNAKA RVDSHWKKQP LGSTNGNGNG AVPPKVNEGG VSAFLRSNSV RNRVPTKTTV 
EPTKVTVKSS SSENVNEPTL KREDSNLSKK SLTKLRAALA KPVMGVSGIR REPVAVSRKE 
AETKKELPET KKDSLEVKKD ATRMPLIRGN SAVTTTTSTM PTTMSLSSKR LAGIEDIDAN 
DKENLVLVSE YVNDIYDYLY QVELEQPIHK DHLAGQKEVS HKMRAVLIDW INEVHLQFHL 
AAETFQLAVA IIDRYLQVVK DTKRTYLQLV GVTALFIATK YEELFPPAIG DFVFITDDTY 
TARQIRQMEL QIFKAIDCNL SRPLPIHFLR RYSKAAGAED EHHTMSKYFI ELASVDYEMA 
TYRPSEIAAA SLFLSLHLLN GNHRAGTGFN DRHWTPTLTF YSRYSAAHLR PITRLIAKLA 
RDAPQAKLKA IYNKYQGSKF QKIALRTELT GALMDSIVGQ SQRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CycB

Associated with

Other Information

The roles of Drosophila cyclins A and B in mitotic control. PubMed ID: 2139805

The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. PubMed ID: 2142452

3' non-translated sequences in Drosophila cyclin B transcripts direct posterior pole accumulation late in oogenesis and peri-nuclear association in syncytial embryos. PubMed ID: 1451670

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis. PubMed ID: 2564167

An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells. PubMed ID: 17372656

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897