Details for: MED23

Gene ID: 37639

Symbol: MED23

Ensembl ID: FBgn0034795

Description: Mediator complex subunit 23

Associated with

  • Epigenetic regulation by wdr5-containing histone modifying complexes
    (R-DME-9917777)
  • Epigenetic regulation of adipogenesis genes by mll3 and mll4 complexes
    (R-DME-9851695)
  • Epigenetic regulation of gene expression
    (R-DME-212165)
  • Epigenetic regulation of gene expression by mll3 and mll4 complexes
    (R-DME-9818564)
  • Gene expression (transcription)
    (R-DME-74160)
  • Mll4 and mll3 complexes regulate expression of pparg target genes in adipogenesis and hepatic steatosis
    (R-DME-9841922)
  • Mediator complex
    (GO:0016592)
  • Positive regulation of gene expression
    (GO:0010628)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Transcription coregulator activity
    (GO:0003712)
  • Transcription regulator complex
    (GO:0005667)

Other Information

Genular Protein ID: 2548339202

Symbol: MED23_DROME

Name: Mediator of RNA polymerase II transcription subunit 23

UniProtKB Accession Codes:

Q9W1X7 A2RVE3

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 EMBL 2 EnsemblMetazoa 1 FlyBase 1 GO 5 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SMR 1 STRING 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 15297616

Title: MED16 and MED23 of Mediator are coactivators of lipopolysaccharide- and heat-shock-induced transcriptional activators.

PubMed ID: 15297616

DOI: 10.1073/pnas.0401985101

Sequence Information:

  • Length: 1439
  • Mass: 167065
  • Checksum: 1E07DD5F62EE5A81
  • Sequence:
    • METQVIDTVN EFLKVDSLDE AFVSVIVFKP NTEQERATRF ANDLVTAFGN VAQENREQVL 
RLYLLRAAGA SGYHIKVLMA ALVKLVDAHV ITARMLCDKV LMCEKLDFEH RTFWIESFRL 
IKRVIVQVDY KGVREIMKVC RDKAQWFPLN VNVTYMPQLL AVEDILRFIF DRNNCLLPAY 
FIANEIMRPF PYHWKLNRLM TDFVEEFRTT AQMVSIIGHA SMLPIVEHFG YADHMMNSWR 
LDHNTLKFNF KGSLPYEPEL LEEQKPLLRY VLEQPYSREM VSQMLNLQKH QKQRYNALEE 
QLVNLIVQAM EMTEANDATA GSGFNSSDEQ ITPYEWMWLH LSSQLIYFVL FQFVSFMHIV 
LALHEKLSKL ELRKGRDQLM WILLQFISGS IQKNPITNFL PVFRLFDLLY PELEPLKLPD 
INKSSMVRHM APICVWIHLM KKARVENMNI TRPLPIALKN HYDFLQHLVT ANTMMNMTLG 
NDFRIILICN AYSTNQEYFG RPMGLLLDAL NGTSKSPNGG QIPAVTFSVT VLDSLTVHSK 
MSLIHSFVTQ MLKQAQSKGQ VPAAALLETY ARLLVYTEIE SLGIKGFLSQ LMPTVFKNHA 
WAMLHTLMEM FSYRLHHVPT HYRVQLLSLL HSLSSVPQTN KMQLNLCFES TALRLITSIG 
SAEFQPQFSR YFNDKSPGAV ASNESEELNR VLILTLARSM HVHGGGDEMQ GWCKDFLSNI 
IQHTPHSWPM HSLACFPPAL NEYFTQNNQP PENKQQLKKA VEEEYRTWTS MTNENDIIAH 
FLRPTTNPLF LCLLFKIIWE TENISPVAYK ILEGISARAL STHLRKFCDY LVAEVASSSD 
GRDFIHKCVD TINNMIWKFN VVTIDRVVLC LALRTHEGNE AQVCFLIIQL LLLKASELRN 
RVQEFCKDNN PDHWKQSNWQ DKHLSFHQKY PEKFALDESA SQIPLPVYFS NVCLRFLPVL 
DVVVHRFIEL TITNVHQILG FILDHLSILY KFHDRPITYL YNTLHYYERI LRDRPALKKK 
LVGAITSAFS EIRPPNWSVS EPYKVYLQSQ DSLWTPELSY YMSLIRRLAD TISGKNVFYS 
TDWRFNEFPN APTHALYVTC VELLGLPVAP PLVASNLIDV IVSGYAVIPQ KDIHSYINAV 
GIVLAALPEP YWSGIYDRLQ DMLNTPNMLN WTYRFNAFEL FNFKTVREAM LEKTYAVVLA 
VAHSVFHHMG AFKLAAMTRY LKEKLKPCVR TEQQLLYLCH VFGPFLQRIE LEKPNAVAGI 
AVLLYEILEI VDKHHGPKPL QYMDQICDFL YHIKYIHVGN IIKNESEAII KRLRPLLQMR 
LRFITHLNLE DIHTEKINDN TSNNAITSQT QSPMQTQHQQ QPQQPHQQQQ QQQQQQQQQQ 
QQQQQQQQMQ QQQINAVQTT SVPLGSGGNL QQQQQINQQQ QMYMQHMQQH QHMQNMRHN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.