Dcp 1 | FBgn0010501 | NCBI 37729

Details for: Dcp 1

Gene ID: 37729

Symbol: Dcp 1

Ensembl ID: FBgn0010501

Description: Death caspase-1

Associated with

Activation of caspases through apoptosome-mediated cleavage
(R-DME-111459)
Akt phosphorylates targets in the cytosol
(R-DME-198323)
Apoptosis
(R-DME-109581)
Apoptotic factor-mediated response
(R-DME-111471)
Cytochrome c-mediated apoptotic response
(R-DME-111461)
Death receptor signaling
(R-DME-73887)
Formation of apoptosome
(R-DME-111458)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Intrinsic pathway for apoptosis
(R-DME-109606)
Pip3 activates akt signaling
(R-DME-1257604)
Regulation of the apoptosome activity
(R-DME-9627069)
Regulation of tnfr1 signaling
(R-DME-5357905)
Rna polymerase ii transcription
(R-DME-73857)
Signal transduction
(R-DME-162582)
Tnf signaling
(R-DME-75893)
Tp53 regulates transcription of caspase activators and caspases
(R-DME-6803207)
Tp53 regulates transcription of cell death genes
(R-DME-5633008)
Transcriptional regulation by tp53
(R-DME-3700989)
Apoptotic process
(GO:0006915)
Bir domain binding
(GO:1990525)
Cellular response to starvation
(GO:0009267)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis
(GO:0097200)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Execution phase of apoptosis
(GO:0097194)
Mitochondrial matrix
(GO:0005759)
Negative regulation of neuromuscular synaptic transmission
(GO:1900074)
Negative regulation of toll signaling pathway
(GO:0045751)
Neuronal cell body
(GO:0043025)
Neuronal ribonucleoprotein granule
(GO:0071598)
Neuron remodeling
(GO:0016322)
Nurse cell apoptotic process
(GO:0045476)
Oogenesis
(GO:0048477)
Ovarian nurse cell to oocyte transport
(GO:0007300)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of macroautophagy
(GO:0016239)
Positive regulation of neuron apoptotic process
(GO:0043525)
Programmed cell death
(GO:0012501)
Programmed cell death involved in cell development
(GO:0010623)
Protein binding
(GO:0005515)
Proteolysis
(GO:0006508)

Other Information

Proteins

Caspase-1

Genular Protein ID: 2672719499

Symbol: CASP1_DROME

Name: Caspase-1

UniProtKB Accession Codes:

O02002 Q9W1N0

Database IDs:

Citations:

PubMed ID: 8999799

Title: DCP-1, a Drosophila cell death protease essential for development.

PubMed ID: 8999799

DOI: 10.1126/science.275.5299.536

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

Sequence Information:

Length: 323
Mass: 35927
Checksum: B5FF0FF75EB8E2BD
Sequence:

MTDECVTRNY GVGIRSPNGS ENRGSFIMAD NTDAKGCTPE SLVVGGATAA SPLPANKFVA 
RMPVERYASE YNMSHKHRGV ALIFNHEFFD IPSLKSRTGT NVDAQELKKA FENLGFAVSV 
HKDCKLRDIL KHVGKAAELD HTDNDCLAVA ILSHGEHGYL YAKDTQYKLD NIWHYFTATF 
CPSLAGKPKL FFIQACQGDR LDGGITLEKG VTETDGESST SYKIPIHADF LFSYSTIPGY 
FSWRNINNGS WYMQSLIREL NANGKKYDLL TLLTFVNQRV ALDFESNVPA TPMMDRQKQI 
PCLTSMLTRI LRFGDKPNGN KAG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.