Details for: Brca2

Gene ID: 37916

Symbol: Brca2

Ensembl ID: FBgn0050169

Description: BRCA2, DNA repair associated

Associated with

  • Dna repair
    (GO:0006281)
  • Dna synthesis involved in double-strand break repair via homologous recombination
    (GO:0043150)
  • Double-strand break repair via homologous recombination
    (GO:0000724)
  • Meiotic dna repair synthesis involved in reciprocal meiotic recombination
    (GO:0010778)
  • Meiotic recombination checkpoint signaling
    (GO:0051598)
  • Nucleus
    (GO:0005634)
  • Protein binding
    (GO:0005515)
  • Response to camptothecin
    (GO:1901563)

Other Information

Genular Protein ID: 1612425641

Symbol: BRCA2_DROME

Name: N/A

UniProtKB Accession Codes:

Q9W157 B2CPK7 B2CPK8 Q494G5 Q8MRU0

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 5 EnsemblMetazoa 1 FlyBase 1 GO 8 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PRO 1 PROSITE 1 PaxDb 1 PhylomeDB 1 Proteomes 1 RefSeq 1 STRING 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 17822964

Title: Functional analysis of Drosophila melanogaster BRCA2 in DNA repair.

PubMed ID: 17822964

DOI: 10.1016/j.dnarep.2007.07.013

PubMed ID: 18266476

Title: Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint.

PubMed ID: 18266476

DOI: 10.1371/journal.pgen.0040031

PubMed ID: 22976300

Title: Cyclin G is involved in meiotic recombination repair in Drosophila melanogaster.

PubMed ID: 22976300

DOI: 10.1242/jcs.113902

Sequence Information:

  • Length: 971
  • Mass: 108649
  • Checksum: 9232DE2A667672CE
  • Sequence:
    • MDQNGASGSH PNRLSQGRGA HARERGATVS AAANRSNIID EMAKICEADR QTFAIARRTR 
GHERLAVDNS DFVAVEDLIL SYAEPTPEDQ VEMIMSDFCS SPTYAEDEDE PSHESEPWFR 
FRNKRIRTYS RKRDPKSHKA VQNEKRRGSS GLSVQRDLNT SFTSMACDFD ASSQKIHEVL 
LNLSQYFSAT ATASGPTPVP SQIDLPTEAR QDSGDECFNA ELENLRDDLL QSGFTFEASF 
YENEHEQEGP GTMADTIYGD SMQSVPTTRL RLESGKRNVW SDADSTLKKA DVEIAENKKL 
LMGQTQAKNV DIEENTNFIL EGIPLSEWLT PMELPEISKD VIKHIPDKKL KLEPSSQKEQ 
KSSKDSNASK VRGASKQSCD INTKNEGTTI LDQPNAAEQE NLLNDGELLE EFLFNDWQPM 
QCSNGPSTSK NAIQGPKENI NSINLDDKEQ PEKQTPNKSQ TISSHQLNGI RKKSFKFIEV 
SEEMKIKGEE FVDKVVSGLY HFSHKCNLRT EEYSDNHSQV MESTQCAEFK SAPSKPIEIL 
DGKETYNAIA KVDVGEINGK FSPLNNDTIA EPEFCGFRTA SNKAIPISEK MKIKTAEFMA 
EFQSKETIQQ NDYLVHQPND KPTSVGLDTA LKRSIESSEE MRSKASKLVV VDTTMREPHQ 
PTLDPVCRDL NESQFFGFRT ASNKAIEITE AMEKRGAMFL AQSKATDQLN GWQPSDFPDV 
LPTSPNNEIH SINVENNKAV NTKTVSETEF FGFRTASNKG IVISENTKIK VAQFMSEFQA 
ADASTDSNQP TVISEESRNI DAKFVDEAAA EDSANKPTFC NVQSLKNTSD IEHFKHDFFV 
EHSAKEEHPL CSQPLVRTPR RSQEIHSSLS QLAGKSPLDQ ATKKSVIARR NLLSLKRKRK 
IILSTETSTS CALPTMERFA PKPSSTSTPL ADRDLNRSKD CTKNRQDAED MSPICMQPKK 
SRRLGLSRSR Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.