Orc4 | FBgn0023181 | NCBI 37970

Details for: Orc4

Gene ID: 37970

Symbol: Orc4

Ensembl ID: FBgn0023181

Description: Origin recognition complex subunit 4

Associated with

Activation of atr in response to replication stress
(R-DME-176187)
Activation of the pre-replicative complex
(R-DME-68962)
Assembly of the orc complex at the origin of replication
(R-DME-68616)
Assembly of the pre-replicative complex
(R-DME-68867)
Cdc6 association with the orc:origin complex
(R-DME-68689)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Cell cycle checkpoints
(R-DME-69620)
Dna replication pre-initiation
(R-DME-69002)
G1/s transition
(R-DME-69206)
G2/m checkpoints
(R-DME-69481)
Mitotic g1 phase and g1/s transition
(R-DME-453279)
Orc1 removal from chromatin
(R-DME-68949)
S phase
(R-DME-69242)
Switching of origins to a post-replicative state
(R-DME-69052)
Synthesis of dna
(R-DME-69239)
Atp hydrolysis activity
(GO:0016887)
Dna binding
(GO:0003677)
Dna replication
(GO:0006260)
Dna replication initiation
(GO:0006270)
Dna replication origin binding
(GO:0003688)
Nuclear origin of replication recognition complex
(GO:0005664)
Nuclear pore
(GO:0005643)
Nucleus
(GO:0005634)
Origin recognition complex
(GO:0000808)
Protein binding
(GO:0005515)
Ribonucleoprotein complex binding
(GO:0043021)

Other Information

Proteins

Q9W102_DROME

Genular Protein ID: 347768728

Symbol: Q9W102_DROME

Name: N/A

UniProtKB Accession Codes:

Q9W102

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

PubMed ID: 25762138

Title: Crystal structure of the eukaryotic origin recognition complex.

PubMed ID: 25762138

DOI: 10.1038/nature14239

PubMed ID: 32848132

Title: Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.

PubMed ID: 32848132

DOI: 10.1038/s41467-020-18067-7

Sequence Information:

Length: 459
Mass: 51936
Checksum: C06BD480DD13B200
Sequence:

MPEADRELVS IRRFLKERLQ RDYTTLRGYA KERSNVRLLL QRTAEMGESN SLLLLGPRGS 
GKTTLINSVL ADLLPNKSFG ENTLIVHLDG NLHTDDRVAL KSITVQMQLE NAADGKVFGS 
FAENLAFLLQ CLKAGGKHSK SVIFILEEFD LFCAHHNQTL LYNLFDVSQS AQAPICVLGV 
TCRLDVIELL EKRVKSRFSH RQVFLFPSLR RFEDYVDLCR DLLSLPTGNS LLLAAEKIYN 
LQNIQSGALY FSRNHFDPGE YGFSPRLRDA WNKQICKVLA TQQARSTLQA LHDFDISEAY 
LKNFLFRLVA HLRPQSPHIT AEKMAAVGSQ FEGDDKIELL CGLSVLELCL IIAIKHHSQI 
YDRDSFNFEI IYARFSKFAK VSTTMQAVER SIVLKAFEHL RIAELIMPLT GGAGGGVGKV 
QKEFEMHKLA LTYSQIHHCM QRYQALPTEV AQWAQSSLI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Orc4

Associated with

Other Information

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. PubMed ID: 12537568

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. PubMed ID: 12537573

Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. PubMed ID: 12537574

Combined evidence annotation of transposable elements in genome sequences. PubMed ID: 16110336

The Release 5.1 annotation of Drosophila melanogaster heterochromatin. PubMed ID: 17569856

Sequence finishing and mapping of Drosophila melanogaster heterochromatin. PubMed ID: 17569867

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. PubMed ID: 26109357

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. PubMed ID: 26109356

The Release 6 reference sequence of the Drosophila melanogaster genome. PubMed ID: 25589440

Crystal structure of the eukaryotic origin recognition complex. PubMed ID: 25762138

Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. PubMed ID: 32848132