Details for: Pdk1

Gene ID: 38017

Symbol: Pdk1

Ensembl ID: FBgn0020386

Description: Phosphoinositide-dependent kinase 1

Associated with

Other Information

Genular Protein ID: 1760842734

Symbol: PDPK1_DROME

Name: 3-phosphoinositide-dependent protein kinase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10336630

Title: Sex-specific transcripts of the Dstpk61 serine/threonine kinase gene in Drosophila melanogaster.

PubMed ID: 10336630

DOI: 10.1046/j.1432-1327.1999.00404.x

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 9368760

Title: 3-phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

PubMed ID: 9368760

DOI: 10.1016/s0960-9822(06)00336-8

PubMed ID: 11115766

Title: The Dstpk61 locus of Drosophila produces multiple transcripts and protein isoforms, suggesting it is involved in multiple signalling pathways.

PubMed ID: 11115766

DOI: 10.1677/joe.0.1670391

PubMed ID: 11301252

Title: A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila.

PubMed ID: 11301252

DOI: 10.1016/s0960-9822(01)00124-5

PubMed ID: 11344272

Title: Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

PubMed ID: 11344272

DOI: 10.1073/pnas.101596998

PubMed ID: 11752451

Title: PDK1 regulates growth through Akt and S6K in Drosophila.

PubMed ID: 11752451

DOI: 10.1073/pnas.011318098

PubMed ID: 11862217

Title: dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.

PubMed ID: 11862217

DOI: 10.1038/ncb763

PubMed ID: 15238523

Title: A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage.

PubMed ID: 15238523

DOI: 10.1534/genetics.103.023184

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 836
  • Mass: 94079
  • Checksum: CA274D2265D17AE2
  • Sequence:
  • MKCKSWSNKI NNYVVRKIKS IKINGTQQQL QLPGSGASGI AAAAVITVAS DCGENCSSNG 
    TEHQQHFNIA TTTATSATEA TMPAMAKEKA SATVSLGESN FRDINLKDLA VVVEAASRLH 
    HQQNVCGCGA VSSTENNNNS RYGSSKYLTN GHTSPLAAAV ASNSSSVATT PHCRMLHNCS 
    LQQYQNDIRQ QTEILDMLRQ QHQQGYQSQQ QQQQPQQQQE QQQQQEQSQQ QQQLQNPAPR 
    RSPNDFIFGR YIGEGSYSIV YLAVDIHSRR EYAIKVCEKR LILRERKQDY IKREREVMHQ 
    MTNVPGFVNL SCTFQDQRSL YFVMTYARKG DMLPYINRVG SFDVACTRHY AAELLLACEH 
    MHRRNVVHRD LKPENILLDE DMHTLIADFG SAKVMTAHER ALATEHCSEQ RRSNSDEDDE 
    DSDRLENEDE DFYDRDSEEL DDGDDEQQQE EMDSPRHRQR RYNRHRKASF VGTAQYVSPE 
    VLQNGPITPA ADLWALGCIV YQMIAGLPPF RGSNDYVIFK EILDCAVDFP QGFDKDAEDL 
    VRKLLRVDPR DRLGAQDEFG YYESIRAHPF FAGIDWQTLR QQTPPPIYPY LPGVSQDEDF 
    RSSYTVPGDL EPGLDERQIS RLLSAELGVG SSVAMPVKRS TAKNSFDLND AEKLQRLEQQ 
    KTDKWHVFAD GEVILKKGFV NKRKGLFARK RMLLLTTGPR LIYIDPVQMI KKGEIPWSPD 
    LRAEYKNFKI FFVHTPNRTY YLDDPEGYAI HWSEAIENMR KLAYGDPSST SAVSCSSGSS 
    NSLAVISNSS AASSSNSPTV KRSSPVNAPQ ASTASDNRTL GSTRTGTSPS KKTASK

Genular Protein ID: 856269984

Symbol: A4V166_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 539
  • Mass: 60954
  • Checksum: B9B864D2527D7260
  • Sequence:
  • MHQMTNVPGF VNLSCTFQDQ RSLYFVMTYA RKGDMLPYIN RVGSFDVACT RHYAAELLLA 
    CEHMHRRNVV HRDLKPENIL LDEDMHTLIA DFGSAKVMTA HERALATEHC SEQRRSNSDE 
    DDEDSDRLEN EDEDFYDRDS EELDDGDDEQ QQEEMDSPRH RQRRYNRHRK ASFVGTAQYV 
    SPEVLQNGPI TPAADLWALG CIVYQMIAGL PPFRGSNDYV IFKEILDCAV DFPQGFDKDA 
    EDLVRKLLRV DPRDRLGAQD EFGYYESIRA HPFFAGIDWQ TLRQQTPPPI YPYLPGVSQD 
    EDFRSSYTVP GDLEPGLDER QISRLLSAEL GVGSSVAMPV KRSTAKNSFD LNDAEKLQRL 
    EQQKTDKWHV FADGEVILKK GFVNKRKGLF ARKRMLLLTT GPRLIYIDPV QMIKKGEIPW 
    SPDLRAEYKN FKIFFVHTPN RTYYLDDPEG YAIHWSEAIE NMRKLAYGDP SSTSAVSCSS 
    GSSNSLAVIS NSSAASSSNS PTVKRSSPVN APQASTASDN RTLGSTRTGT SPSKKTASK

Genular Protein ID: 1995936650

Symbol: A4V164_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 755
  • Mass: 85613
  • Checksum: 6375A99A25089FDD
  • Sequence:
  • MPAMAKEKAS ATVSLGESNF RDINLKDLAV VVEAASRLHH QQNVCGCGAV SSTENNNNSR 
    YGSSKYLTNG HTSPLAAAVA SNSSSVATTP HCRMLHNCSL QQYQNDIRQQ TEILDMLRQQ 
    HQQGYQSQQQ QQQPQQQQEQ QQQQEQSQQQ QQLQNPAPRR SPNDFIFGRY IGEGSYSIVY 
    LAVDIHSRRE YAIKVCEKRL ILRERKQDYI KREREVMHQM TNVPGFVNLS CTFQDQRSLY 
    FVMTYARKGD MLPYINRVGS FDVACTRHYA AELLLACEHM HRRNVVHRDL KPENILLDED 
    MHTLIADFGS AKVMTAHERA LATEHCSEQR RSNSDEDDED SDRLENEDED FYDRDSEELD 
    DGDDEQQQEE MDSPRHRQRR YNRHRKASFV GTAQYVSPEV LQNGPITPAA DLWALGCIVY 
    QMIAGLPPFR GSNDYVIFKE ILDCAVDFPQ GFDKDAEDLV RKLLRVDPRD RLGAQDEFGY 
    YESIRAHPFF AGIDWQTLRQ QTPPPIYPYL PGVSQDEDFR SSYTVPGDLE PGLDERQISR 
    LLSAELGVGS SVAMPVKRST AKNSFDLNDA EKLQRLEQQK TDKWHVFADG EVILKKGFVN 
    KRKGLFARKR MLLLTTGPRL IYIDPVQMIK KGEIPWSPDL RAEYKNFKIF FVHTPNRTYY 
    LDDPEGYAIH WSEAIENMRK LAYGDPSSTS AVSCSSGSSN SLAVISNSSA ASSSNSPTVK 
    RSSPVNAPQA STASDNRTLG STRTGTSPSK KTASK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.