Details for: mth

Gene ID: 38058

Symbol: mth

Ensembl ID: FBgn0023000

Description: methuselah

Associated with

Other Information

Genular Protein ID: 2368228161

Symbol: MTH_DROME

Name: G-protein coupled receptor Mth

UniProtKB Accession Codes:

O97148 B5RJF9 Q9GN21 Q9GN78 Q9GND6 Q9GNE8 Q9GT57 Q9GT58 Q9GT59 Q9GT60 Q9W0R4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEMBL 1 DNASU 1 EMBL 36 EnsemblMetazoa 3 EvolutionaryTrace 1 ExpressionAtlas 1 FlyBase 1 GO 14 Gene3D 3 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PDB 5 PDBsum 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 RefSeq 3 SMR 1 STRING 1 SUPFAM 2 TCDB 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9794765

Title: Extended life-span and stress resistance in the Drosophila mutant methuselah.

PubMed ID: 9794765

DOI: 10.1126/science.282.5390.943

PubMed ID: 10995474

Title: Adaptive evolution of a candidate gene for aging in Drosophila.

PubMed ID: 10995474

DOI: 10.1073/pnas.190338897

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12367510

Title: Presynaptic regulation of neurotransmission in Drosophila by the G protein-coupled receptor methuselah.

PubMed ID: 12367510

DOI: 10.1016/s0896-6273(02)00932-7

PubMed ID: 15133470

Title: The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila.

PubMed ID: 15133470

DOI: 10.1038/ncb1133

PubMed ID: 19672878

Title: The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides.

PubMed ID: 19672878

DOI: 10.1002/pro.221

PubMed ID: 11274391

Title: Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan.

PubMed ID: 11274391

DOI: 10.1073/pnas.051625298

PubMed ID: 17546039

Title: Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor.

PubMed ID: 17546039

DOI: 10.1038/nchembio.2007.2

Sequence Information:

  • Length: 514
  • Mass: 59644
  • Checksum: F2A5370CECCD1D5C
  • Sequence:
    • MKTLLVLRIS TVILVVLVIQ KSYADILECD YFDTVDISAA QKLQNGSYLF EGLLVPAILT 
GEYDFRILPD DSKQKVARHI RGCVCKLKPC VRFCCPHDHI MDNGVCYDNM SDEELAELDP 
FLNVTLDDGS VSRRHFKNEL IVQWDLPMPC DGMFYLDNRE EQDKYTLFEN GTFFRHFDRV 
TLRKREYCLQ HLTFADGNAT SIRIAPHNCL IVPSITGQTV VMISSLICMV LTIAVYLFVK 
KLQNLHGKCF ICYMVCLFMG YLFLLLDLWQ ISISFCKPAG FLGYFFVMAA FFWLSVISLH 
LWNTFRGSSH KANRFLFEHR FLAYNTYAWG MAVVLTGITV LADNIVENQD WNPRVGHEGH 
CWIYTQAWSA MLYFYGPMVF LIAFNITMFI LTAKRILGVK KDIQNFAHRQ ERKQKLNSDK 
QTYTFFLRLF IIMGLSWSLE IGSYFSQSNQ TWANVFLVAD YLNWSQGIII FILFVLKRST 
WRLLQESIRG EGEEVNNSEE EISLENTTTR NVLL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.