Details for: KIR2DS1

Gene ID: 3806

Symbol: KIR2DS1

Description: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1

Associated with

Other Information

Genular Protein ID: 3702217474

Symbol: KI2S1_HUMAN

Name: CD158 antigen-like family member H

UniProtKB Accession Codes:

Q14954 K7QUS8 O43471

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 12 GO 4 Gene3D 1 GeneCards 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PRO 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 SignaLink 1 UCSC 1 UniProtKB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8627176

Title: The human leukocyte antigen (HLA)-C-specific 'activatory' or 'inhibitory' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

PubMed ID: 8627176

DOI: 10.1084/jem.183.2.645

PubMed ID: 9430221

Title: Human diversity in killer cell inhibitory receptor genes.

PubMed ID: 9430221

DOI: 10.1016/s1074-7613(00)80394-5

PubMed ID: 23394822

Title: Recombinant structures expand and contract inter and intragenic diversification at the KIR locus.

PubMed ID: 23394822

DOI: 10.1186/1471-2164-14-89

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 18624290

Title: Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.

PubMed ID: 18624290

DOI: 10.1002/eji.200838434

PubMed ID: 18682925

Title: Extracellular domain alterations impact surface expression of stimulatory natural killer cell receptor KIR2DS5.

PubMed ID: 18682925

DOI: 10.1007/s00251-008-0322-2

PubMed ID: 23715743

Title: DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells.

PubMed ID: 23715743

DOI: 10.1189/jlb.0213093

Sequence Information:

  • Length: 304
  • Mass: 33618
  • Checksum: FD323A0EB48B13C2
  • Sequence:
    • MSLTVVSMAC VGFFLLQGAW PHEGVHRKPS LLAHPGRLVK SEETVILQCW SDVMFEHFLL 
HREGMFNDTL RLIGEHHDGV SKANFSISRM KQDLAGTYRC YGSVTHSPYQ LSAPSDPLDI 
VIIGLYEKPS LSAQPGPTVL AGENVTLSCS SRSSYDMYHL SREGEAHERR LPAGTKVNGT 
FQANFPLGPA THGGTYRCFG SFRDSPYEWS KSSDPLLVSV TGNPSNSWPS PTEPSSETGN 
PRHLHVLIGT SVVKIPFTIL LFFLLHRWCS DKKNAAVMDQ EPAGNRTVNS EDSDEQDHQE 
VSYA

Genular Protein ID: 1825478390

Symbol: B1N8M6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B1N8M6

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 2 CTD 1 DNASU 1 EMBL 8 Ensembl 3 GO 1 Gene3D 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 Pfam 1 Proteomes 2 RefSeq 2 SAM 3 SMART 2 SMR 1 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 18396209

Title: Limited allelic diversity of stimulatory two-domain killer cell immunoglobulin-like receptors.

PubMed ID: 18396209

DOI: 10.1016/j.humimm.2008.01.009

Sequence Information:

  • Length: 304
  • Mass: 33630
  • Checksum: E1F157B22B0D6A22
  • Sequence:
    • MSLLVVSMAC VGFFLLQGAW PHEGVHRKPS LLAHPGRLVK SEETVILQCW SDVMFEHFLL 
HREGMFNDTL RLIGEHHDGV SKANFSISRM KQDLAGTYRC YGSVTHSPYQ LSAPSDPLDI 
VIIGLYEKPS LSAQPGPTVL AGENVTLSCS SRSSYDMYHL SREGEAHERR LPAGTKVNGT 
FQANFPLGPA THGGTYRCFG SFRDSPYEWS KSSDPLLVSV TGNPSNSWPS PTEPSSETGN 
PRHLHVLIGT SVVKIPFTIL LFFLLHRWCS DKKNAAVMDQ EPAGNRTVNS EDSDEQDHQE 
VSYA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.