Details for: MED14

Gene ID: 38073

Symbol: MED14

Ensembl ID: FBgn0035145

Description: Mediator complex subunit 14

Associated with

  • Epigenetic regulation by wdr5-containing histone modifying complexes
    (R-DME-9917777)
  • Epigenetic regulation of adipogenesis genes by mll3 and mll4 complexes
    (R-DME-9851695)
  • Epigenetic regulation of gene expression
    (R-DME-212165)
  • Epigenetic regulation of gene expression by mll3 and mll4 complexes
    (R-DME-9818564)
  • Gene expression (transcription)
    (R-DME-74160)
  • Mll4 and mll3 complexes regulate expression of pparg target genes in adipogenesis and hepatic steatosis
    (R-DME-9841922)
  • Core mediator complex
    (GO:0070847)
  • Mediator complex
    (GO:0016592)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of transcription initiation by rna polymerase ii
    (GO:0060260)
  • Transcription coregulator activity
    (GO:0003712)

Other Information

Genular Protein ID: 265582810

Symbol: MED14_DROME

Name: Mediator of RNA polymerase II transcription subunit 14

UniProtKB Accession Codes:

Q9W0P8 Q5U1E1 Q8IRI9 Q961S0 Q9GYW6

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 DIP 1 EMBL 5 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 1 GO 5 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 4 PhylomeDB 1 Proteomes 1 RefSeq 2 SMR 1 STRING 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11259581

Title: Drosophila Mediator complex is broadly utilized by diverse gene-specific transcription factors at different types of core promoters.

PubMed ID: 11259581

DOI: 10.1128/mcb.21.7.2312-2323.2001

PubMed ID: 16751183

Title: Coactivator cross-talk specifies transcriptional output.

PubMed ID: 16751183

DOI: 10.1101/gad.1418806

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 1553
  • Mass: 172341
  • Checksum: 71CF4DA8A23A5023
  • Sequence:
    • MAPTPLPLEQ MPGVGGGGGG YLPAAQEGGP RINTMSMSVL IDFIIQRTYH ELTVLAELLP 
RKTDMERKVE IYNYAARTRH LFTRLNALVK WGNSVSKVDK SSQIMSFLDK QNMLFVETAD 
MLARMSRETL VRARLPNFHI PAAVEVLTTG TYNRLPTCIR ERIVPADAIT PAEKRQTLLR 
LNQVIQHRLV TGKLLPQMRE FRIRNGRVTF EVKHEFSVSL TVMGDNPTVP WRLLDIDVLV 
EDKETGDGKS LVHPLQVNYI HQLIQARLVE NPNALSEVYN CLHYFCQSLQ LEVLYTQTLR 
LNYERLDDNN ITVEEYVPGV KLTVSYWRDL KSELGYRLTV QSDPSEIGRP LAVVHVPSLG 
AKESAEVADR AVRSEHLSME RLIVHTVYIR SVSRLSDLKL EFQAFLKDVD FNLQGTPAIL 
TVPVLSPCLR AEQIHITIDT HTGMFRCHVP KHLDCPIMEE MQDCLNGDRS KLPALLSELR 
FWITHRRCDK TLQHLPATAT ETLPFLVQPD QEILQPGRHK IYVKLHRHPN IVLVVQLKEK 
TTMPNEMEYT FHLGFVAYQK DELDVIDDSA MQLVSIVAQP HSDIPKCYTK LMRLIEFDTF 
VATHGPGTEV DAEVSPHKRK SNGDLLAPPA KQQKTIFPAY FIPELAHVVA MCDEKIPFMN 
LAQTLSKHNI PHSGLQVEAN ATSLVLKILA LPQPGKTTFA TQQQQQQGAP AVAGENKPSG 
TSGLPKIDSH VWDDLMRRVL SISIRSQTNK NSQVRIWVVE FVFYSTPLQS SHPKEQGSRR 
TVYLTYEQAN YDFSKTVEDL LNDWSKIVYL YTLVYDFAEQ LLNKRLSLCD MLVVKSYSYM 
NLLLGYGPKK EVSCNIYWSV QSHGFRLTFV GGMSAVNGHS MMRDQLAQHL NQQHSITQIA 
QILHETYNPL SSIAKLPVLP FLGIPRPQVP VLSFCVLAQS PCLIRLTYQA VYCLELRFRA 
NRLVSIRDGA SSRFERNVVE EFTPIQGLKA FLSKYVDESA VYRGRASHED DNPLSPMGME 
DNFGGPSSVA GVSAGGSSPF LGTGMRGPQS PRDSGLRFPA PHTPPSSSNP HTPASPHPSA 
GAGGGSGPQG HGNFNLTSPP APHMPHPSPS GLMPSSPLNP QPSPHMVHSP GPNTLYMQSH 
QDSPFTAMSP ANNNWPGSPS MPRPSPRPGQ SPDHKSTGGG AGVAGGTDRG GSRGTLNRPW 
AGAVPTLLTH EALETLCRPS PYPNKDINVP DMSPLERFLG CVYMRRQLHR NIQSEETLTA 
LNSTEPGVVL FKVDGLQCQV VLNQMHMQTL HLKVSQLPPM PDKHPPPFQL SQDDLLVIEQ 
YFDTRVAAPP YRPNSLHSIC RLLNLPAQVL KDFVQIMRLD LKPELGGDQL KWTVQICLRM 
PPSAVPIVPS GNACVVMGRM KILFFLQITR IPYGAVIGVG KDWKDSPSLV LPIVYDIQTN 
VTQLAERTGQ VISPTMTAAS TLLRRFAEFN AQQNQCTLFP AITDLLTNLQ LAAEMPQPPP 
NQSIGPPVGV GVGVGSSPNP MMPMQQLPQQ VGPQGPVGPG GYPQMGPNPG GPQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.