Details for: KIR2DS5

Gene ID: 3810

Symbol: KIR2DS5

Description: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5

Associated with

Other Information

Genular Protein ID: 1522055031

Symbol: KI2S5_HUMAN

Name: CD158 antigen-like family member G

UniProtKB Accession Codes:

Q14953 A0A0C4ZMZ1

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 BioMuta 1 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 5 GO 5 Gene3D 1 GeneCards 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PRO 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 Pharos 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 SUPFAM 1 SignaLink 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8662091

Title: Alternatively spliced forms of human killer inhibitory receptors.

PubMed ID: 8662091

DOI: 10.1007/bf02602590

PubMed ID: 28569259

Title: Revealing complete complex KIR haplotypes phased by long-read sequencing technology.

PubMed ID: 28569259

DOI: 10.1038/gene.2017.10

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 18624290

Title: Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.

PubMed ID: 18624290

DOI: 10.1002/eji.200838434

PubMed ID: 18682925

Title: Extracellular domain alterations impact surface expression of stimulatory natural killer cell receptor KIR2DS5.

PubMed ID: 18682925

DOI: 10.1007/s00251-008-0322-2

PubMed ID: 24269691

Title: Allelic variation of killer cell immunoglobulin-like receptor 2DS5 impacts glycosylation altering cell surface expression levels.

PubMed ID: 24269691

DOI: 10.1016/j.humimm.2013.11.012

PubMed ID: 28685972

Title: KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans.

PubMed ID: 28685972

DOI: 10.1002/iid3.178

Sequence Information:

  • Length: 304
  • Mass: 33698
  • Checksum: 83AFBB6A08D8DC9B
  • Sequence:
    • MSLMVISMAC VAFFLLQGAW PHEGFRRKPS LLAHPGPLVK SEETVILQCW SDVMFEHFLL 
HREGTFNHTL RLIGEHIDGV SKGNFSIGRM TQDLAGTYRC YGSVTHSPYQ LSAPSDPLDI 
VITGLYEKPS LSAQPGPTVL AGESVTLSCS SRSSYDMYHL SREGEAHERR LPAGPKVNRT 
FQADFPLDPA THGGTYRCFG SFRDSPYEWS KSSDPLLVSV TGNSSNSWPS PTEPSSETGN 
PRHLHVLIGT SVVKLPFTIL LFFLLHRWCS NKKNASVMDQ GPAGNRTVNR EDSDEQDHQE 
VSYA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.