Details for: Ptp61F

Gene ID: 38160

Symbol: Ptp61F

Ensembl ID: FBgn0267487

Description: Protein tyrosine phosphatase 61F

Associated with

  • Axon guidance
    (GO:0007411)
  • Cellular response to hypoxia
    (GO:0071456)
  • Cellular response to mechanical stimulus
    (GO:0071260)
  • Cytoplasm
    (GO:0005737)
  • Germ-band extension
    (GO:0007377)
  • Mitochondrial envelope
    (GO:0005740)
  • Mitotic cell cycle
    (GO:0000278)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of epidermal growth factor receptor signaling pathway
    (GO:0042059)
  • Negative regulation of erk1 and erk2 cascade
    (GO:0070373)
  • Negative regulation of insulin receptor signaling pathway
    (GO:0046627)
  • Negative regulation of jnk cascade
    (GO:0046329)
  • Negative regulation of organ growth
    (GO:0046621)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Negative regulation of receptor signaling pathway via jak-stat
    (GO:0046426)
  • Negative regulation of torc1 signaling
    (GO:1904262)
  • Negative regulation of vascular endothelial growth factor receptor signaling pathway
    (GO:0030948)
  • Non-membrane spanning protein tyrosine phosphatase activity
    (GO:0004726)
  • Nucleus
    (GO:0005634)
  • Perinuclear region of cytoplasm
    (GO:0048471)
  • Positive regulation of hippo signaling
    (GO:0035332)
  • Protein binding
    (GO:0005515)
  • Protein kinase binding
    (GO:0019901)
  • Protein sequestering activity
    (GO:0140311)
  • Protein tyrosine phosphatase activity
    (GO:0004725)
  • Regulation of protein localization
    (GO:0032880)
  • Regulation of protein stability
    (GO:0031647)

Other Information

Genular Protein ID: 3344846523

Symbol: PTP61_DROME

Name: Tyrosine-protein phosphatase non-receptor type 61F

UniProtKB Accession Codes:

Q9W0G1 Q27932 Q8SZY3 Q9W0G2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 EC 1 EMBL 12 EnsemblMetazoa 3 ExpressionAtlas 1 FlyBase 1 GO 31 Gene3D 1 GeneTree 1 GenomeRNAi 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 2 PRINTS 1 PRO 1 PROSITE 3 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 6 RefSeq 3 Rhea 3 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8463208

Title: Alternative splicing gives rise to a nuclear protein tyrosine phosphatase in Drosophila.

PubMed ID: 8463208

DOI: 10.1016/s0021-9258(18)53111-2

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 8663600

Title: A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance.

PubMed ID: 8663600

DOI: 10.1074/jbc.271.29.17002

PubMed ID: 9256342

Title: Differential accumulation of DPTP61F alternative transcripts: regulation of a protein tyrosine phosphatase by segmentation genes.

PubMed ID: 9256342

DOI: 10.1016/s0925-4773(97)00046-4

PubMed ID: 12014990

Title: Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases.

PubMed ID: 12014990

DOI: 10.1042/bj20020298

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 21707536

Title: Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.

PubMed ID: 21707536

DOI: 10.1042/bj20110799

Sequence Information:

  • Length: 548
  • Mass: 62105
  • Checksum: C6AF630E2DE3F11C
  • Sequence:
    • MSEQKTSGSG SAAAARLQIE AEYKDKGPQW HRFYKEICET CDREAKEKQF STSESERHTN 
RGLNRYRDVN PYDHSRIVLK RGSVDYINAN LVQLERAERQ YILTQGPLVD TVGHFWLMVW 
EQKSRAVLML NKLMEKKQIK CHLYWPNEMG ADKALKLPHV KLTVELVRLE TYQNFVRRWF 
KLTDLETQQS REVMQFHYTT WPDFGIPSSP NAFLKFLQQV RDSGCLSRDV GPAVVHCSAG 
IGRSGTFCLV DCCLVLIDKY GECNVSKVLC ELRSYRMGLI QTADQLDFSY QAIIEGIKKL 
HDPTFLDAEE PLISNDTETH TLDELPPPLP PRVQSLNLPL APNSGGILSL NMRAAQANGA 
ESIGKELSKD ALNNFINQHD MIHDAEVADS RPLPPLPVRA FNDSDSDEDY LLDDDDEDDT 
DEDEEYETIN EHDADPVNGH VPATTQPHAD DVNANNEKPA VPVDEQHKAN GIDPIPGQLP 
ASPENELKRR KRNEYQASLE QKVNDMKRKQ RENEDKQLAA KKRRSLLTYI AAGVVVGVIC 
AYAYTKLG

Genular Protein ID: 4201226347

Symbol: Q8IRH4_DROME

Name: N/A

UniProtKB Accession Codes:

Q8IRH4

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 4 Gene3D 1 GeneTree 1 InterPro 6 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 2 SAM 2 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 431
  • Mass: 48517
  • Checksum: 3E584E3881A82142
  • Sequence:
    • MVWEQKSRAV LMLNKLMEKK QIKCHLYWPN EMGADKALKL PHVKLTVELV RLETYQNFVR 
RWFKLTDLET QQSREVMQFH YTTWPDFGIP SSPNAFLKFL QQVRDSGCLS RDVGPAVVHC 
SAGIGRSGTF CLVDCCLVLI DKYGECNVSK VLCELRSYRM GLIQTADQLD FSYQAIIEGI 
KKLHDPTFLD AEEPLISNDT ETHTLDELPP PLPPRVQSLN LPLAPNSGGI LSLNMRAAQA 
NGAESIGKEL SKDALNNFIN QHDMIHDAEV ADSRPLPPLP VRAFNDSDSD EDYLLDDDDE 
DDTDEDEEYE TINEHDADPV NGHVPATTQP HADDVNANNE KPAVPVDEQH KANGIDPIPG 
QLPASPENEL KRRKRNEYQA SLEQKVNDMK RKQRENEDKQ LAAKKRRSLL TYIAAGVVVG 
VICAYAYTKL G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.