Details for: ARF6
Associated with
Other Information
Genular Protein ID: 249932781
Symbol: ARF6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1993656
Title: Molecular identification of ADP-ribosylation factor mRNAs and their expression in mammalian cells.
PubMed ID: 1993656
PubMed ID: 14659046
Title: Sequence, genomic organization, and expression of the human ADP-ribosylation factor 6 (ARF6) gene: a class III ARF.
PubMed ID: 14659046
PubMed ID: 9653160
Title: Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning.
PubMed ID: 9653160
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7589240
Title: Myristoylation is required for the intracellular localization and endocytic function of ARF6.
PubMed ID: 7589240
PubMed ID: 11062263
Title: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.
PubMed ID: 11062263
PubMed ID: 11950392
Title: GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.
PubMed ID: 11950392
DOI: 10.1042/bj20020428
PubMed ID: 12847086
Title: ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma.
PubMed ID: 12847086
PubMed ID: 15509780
Title: The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.
PubMed ID: 15509780
PubMed ID: 14978216
Title: Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs.
PubMed ID: 14978216
PubMed ID: 16148947
Title: Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis.
PubMed ID: 16148947
PubMed ID: 15642342
Title: Requirement of phosphatidylinositol-4,5-bisphosphate for HERC1-mediated guanine nucleotide release from ARF proteins.
PubMed ID: 15642342
PubMed ID: 15793564
Title: Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics.
PubMed ID: 15793564
DOI: 10.1038/ncb1244
PubMed ID: 16737952
Title: Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein, ACAP4.
PubMed ID: 16737952
PubMed ID: 17030804
Title: Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1.
PubMed ID: 17030804
PubMed ID: 17398095
Title: The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.
PubMed ID: 17398095
PubMed ID: 17628206
Title: Molecular characterization of Rab11-FIP3 binding to ARF GTPases.
PubMed ID: 17628206
PubMed ID: 17555535
Title: Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta.
PubMed ID: 17555535
PubMed ID: 18400762
Title: ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion.
PubMed ID: 18400762
PubMed ID: 20727515
Title: TBC1D24, an ARF6-interacting protein, is mutated in familial infantile myoclonic epilepsy.
PubMed ID: 20727515
PubMed ID: 19948740
Title: AIP1 functions as Arf6-GAP to negatively regulate TLR4 signaling.
PubMed ID: 19948740
PubMed ID: 20682791
Title: A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.
PubMed ID: 20682791
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21951725
Title: MICAL-L1 is a tubular endosomal membrane hub that connects Rab35 and Arf6 with Rab8a.
PubMed ID: 21951725
PubMed ID: 23603394
Title: EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis.
PubMed ID: 23603394
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25255805
Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
PubMed ID: 25255805
DOI: 10.1038/ncomms5919
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 32103017
Title: NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
PubMed ID: 32103017
PubMed ID: 36017701
Title: AMPK promotes Arf6 activation in a kinase-independent manner upon glucose starvation.
PubMed ID: 36017701
DOI: 10.1242/jcs.259609
PubMed ID: 36250347
Title: Insulin stimulates atypical protein kinase C-mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6-Rac1 signaling.
PubMed ID: 36250347
PubMed ID: 37417384
Title: Enterovirus 71 enters human brain microvascular endothelial cells through an ARF6-mediated endocytic pathway.
PubMed ID: 37417384
DOI: 10.1002/jmv.28915
PubMed ID: 37461827
Title: ARF6 plays a general role in targeting palmitoylated proteins from golgi to the plasma membrane.
PubMed ID: 37461827
DOI: 10.1242/jcs.261319
PubMed ID: 10881192
Title: Structure of Arf6-GDP suggests a basis for guanine nucleotide exchange factors specificity.
PubMed ID: 10881192
DOI: 10.1038/75863
PubMed ID: 11266366
Title: The structural GDP/GTP cycle of human Arf6.
PubMed ID: 11266366
PubMed ID: 16099990
Title: Structural basis for the activation of cholera toxin by human ARF6-GTP.
PubMed ID: 16099990
PubMed ID: 16839550
Title: NMR structural studies of the myristoylated N-terminus of ADP ribosylation factor 6 (Arf6).
PubMed ID: 16839550
PubMed ID: 19644450
Title: The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4.
PubMed ID: 19644450
PubMed ID: 20510928
Title: The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism.
PubMed ID: 20510928
PubMed ID: 21170023
Title: The assembly of a GTPase-kinase signalling complex by a bacterial catalytic scaffold.
PubMed ID: 21170023
DOI: 10.1038/nature09593
PubMed ID: 22939626
Title: Structurally distinct bacterial TBC-like GAPs link Arf GTPase to Rab1 inactivation to counteract host defenses.
PubMed ID: 22939626
PubMed ID: 23940353
Title: Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors.
PubMed ID: 23940353
Sequence Information:
- Length: 175
- Mass: 20082
- Checksum: 49E38E59AEA52B98
- Sequence:
MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE TVTYKNVKFN VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGD GLYEGLTWLT SNYKS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.