Details for: drpr

Gene ID: 38218

Symbol: drpr

Ensembl ID: FBgn0027594

Description: draper

Associated with

Other Information

Genular Protein ID: 3060229155

Symbol: DRPR_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12765609

Title: Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function.

PubMed ID: 12765609

DOI: 10.1016/s0896-6273(03)00289-7

PubMed ID: 15342648

Title: Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages.

PubMed ID: 15342648

DOI: 10.1074/jbc.m408597200

PubMed ID: 16772168

Title: Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis.

PubMed ID: 16772168

DOI: 10.1016/j.neuron.2006.04.027

PubMed ID: 16772169

Title: The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons.

PubMed ID: 16772169

DOI: 10.1016/j.neuron.2006.04.028

PubMed ID: 16772170

Title: Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning.

PubMed ID: 16772170

DOI: 10.1016/j.neuron.2006.05.013

PubMed ID: 18455990

Title: Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neurons.

PubMed ID: 18455990

DOI: 10.1016/j.cell.2008.02.052

PubMed ID: 18984163

Title: Undertaker, a Drosophila Junctophilin, links Draper-mediated phagocytosis and calcium homeostasis.

PubMed ID: 18984163

DOI: 10.1016/j.cell.2008.08.033

PubMed ID: 18432193

Title: Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling.

PubMed ID: 18432193

DOI: 10.1038/nature06901

PubMed ID: 19927123

Title: Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells.

PubMed ID: 19927123

DOI: 10.1038/emboj.2009.343

PubMed ID: 19890048

Title: Identification of lipoteichoic acid as a ligand for draper in the phagocytosis of Staphylococcus aureus by Drosophila hemocytes.

PubMed ID: 19890048

DOI: 10.4049/jimmunol.0901032

PubMed ID: 19707574

Title: Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris.

PubMed ID: 19707574

DOI: 10.1371/journal.pbio.1000184

PubMed ID: 20577216

Title: Activation of autophagy during cell death requires the engulfment receptor Draper.

PubMed ID: 20577216

DOI: 10.1038/nature09127

PubMed ID: 22992958

Title: Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells.

PubMed ID: 22992958

DOI: 10.1242/dev.082776

PubMed ID: 23337816

Title: Role of NPxY motif in Draper-mediated apoptotic cell clearance in Drosophila.

PubMed ID: 23337816

PubMed ID: 22426252

Title: Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury.

PubMed ID: 22426252

DOI: 10.1038/nn.3066

PubMed ID: 23420848

Title: Phosphatidylserine recognition and induction of apoptotic cell clearance by Drosophila engulfment receptor Draper.

PubMed ID: 23420848

DOI: 10.1093/jb/mvt014

PubMed ID: 25111228

Title: Silencing of drpr leads to muscle and brain degeneration in adult Drosophila.

PubMed ID: 25111228

DOI: 10.1016/j.ajpath.2014.06.018

PubMed ID: 24412417

Title: Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila.

PubMed ID: 24412417

DOI: 10.1016/j.neuron.2013.11.021

PubMed ID: 26028435

Title: Draper/CED-1 mediates an ancient damage response to control inflammatory blood cell migration in vivo.

PubMed ID: 26028435

DOI: 10.1016/j.cub.2015.04.037

PubMed ID: 27212238

Title: Corpse engulfment generates a molecular memory that primes the macrophage inflammatory response.

PubMed ID: 27212238

DOI: 10.1016/j.cell.2016.04.049

PubMed ID: 27498858

Title: Insulin-like signaling promotes glial phagocytic clearance of degenerating axons through regulation of Draper.

PubMed ID: 27498858

DOI: 10.1016/j.celrep.2016.07.022

PubMed ID: 27347682

Title: Components of the engulfment machinery have distinct roles in corpse processing.

PubMed ID: 27347682

DOI: 10.1371/journal.pone.0158217

PubMed ID: 30802937

Title: The impact of Megf10/Drpr gain-of-function on muscle development in Drosophila.

PubMed ID: 30802937

DOI: 10.1002/1873-3468.13348

Title: Selective serotonin reuptake inhibitors ameliorate MEGF10 myopathy.

DOI: 10.1093/hmg/ddz064

PubMed ID: 34860835

Title: bfc, a novel serpent co-factor for the expression of croquemort, regulates efferocytosis in Drosophila melanogaster.

PubMed ID: 34860835

DOI: 10.1371/journal.pgen.1009947

Sequence Information:

  • Length: 1031
  • Mass: 113015
  • Checksum: A6A0104917D060A9
  • Sequence:
  • MLPVILIACL AQLVLAQADL KDLDGPNICK RRELYNVDVV YTELQSFQER GSTWCVTFPP 
    RCSTYRIKHR VVNKTKTIAK NRIVRDCCDG YIASAGECVP HCSEPCQHGR CISPEKCKCD 
    HGYGGPACDI NCPPGWYGRN CSMQCDCLNN AVCEPFSGDC ECAKGYTGAR CADICPEGFF 
    GANCSEKCRC ENGGKCHHVS GECQCAPGFT GPLCDMRCPD GKHGAQCQQD CPCQNDGKCQ 
    PETGACMCNP GWTGDVCANK CPVGSYGPGC QESCECYKGA PCHHITGQCE CPPGYRGERC 
    FDECQLNTYG FNCSMTCDCA NDAMCDRANG TCICNPGWTG AKCAERICEA NKYGLDCNRT 
    CECDMEHTDL CHPETGNCQC SIGWSSAQCT RPCTFLRYGP NCELTCNCKN GAKCSPVNGT 
    CLCAPGWRGP TCEESCEPGT FGQDCALRCD CQNGAKCEPE TGQCLCTAGW KNIKCDRPCD 
    LNHFGQDCAK VCDCHNNAAC NPQNGSCTCA AGWTGERCER KCDTGKFGHD CAQKCQCDFN 
    NSLACDATNG RCVCKQDWGG VHCETNCRSG YYGENCDKVC RCLNNSSCDP DSGNCICSAG 
    WTGADCAEPC PPGFYGMECK ERCPEILHGN KSCDHITGEI LCRTGYIGLT CEHPCPAGLY 
    GPGCKLKCNC EHGGECNHVT GQCQCLPGWT GSNCNESCPT DTYGQGCAQR CRCVHHKVCR 
    KADGMCICET GWSGTRCDEV CPEGFYGEHC MNTCACPSAN FQCHAAHGCV CRSGYTGDNC 
    DELIASQRIA DQSENSSRAS VALTLVLMTL FACIIFAVFI YYRRRVSNLK TEIAHVHYTH 
    DTNPPSWPPN HNFDNPVYGM QAETRLLPNN MRSKMNNFDQ RSTMSTDYGD DCNASGRVGS 
    YSINYNHDLL TKNLNADRTN PIVYNESLKE EHVYDEIKHK EGYKDPDEYD HLDYSRPSTS 
    QKPHYHRMND AMLNINQDEE KPSNVKNMTV LLNKPLPPTE PEPQHECFDN TNTNLDNVST 
    ASPSSSPKFL K

Genular Protein ID: 2263339332

Symbol: M9PGU6_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 1042
  • Mass: 114333
  • Checksum: F4D66BE152074BFD
  • Sequence:
  • MLPVILIACL AQLVLAQADL KDLDGPNICK RRELYNVDVV YTELQSFQER GSTWCVTFPP 
    RCSTYRIKHR VVNKTKTIAK NRIVRDCCDG YIASAGECVP HCSEPCQHGR CISPEKCKCD 
    HGYGGPACDI NCPPGWYGRN CSMQCDCLNN AVCEPFSGDC ECAKGYTGAR CADICPEGFF 
    GANCSEKCRC ENGGKCHHVS GECQCAPGFT GPLCDMRCPD GKHGAQCQQD CPCQNDGKCQ 
    PETGACMCNP GWTGDVCANK CPVGSYGPGC QESCECYKGA PCHHITGQCE CPPGYRGERC 
    FDECQLNTYG FNCSMTCDCA NDAMCDRANG TCICNPGWTG AKCAERICEA NKYGLDCNRT 
    CECDMEHTDL CHPETGNCQC SIGWSSAQCT RPCTFLRYGP NCELTCNCKN GAKCSPVNGT 
    CLCAPGWRGP TCEESCEPGT FGQDCALRCD CQNGAKCEPE TGQCLCTAGW KNIKCDRPCD 
    LNHFGQDCAK VCDCHNNAAC NPQNGSCTCA AGWTGERCER KCDTGKFGHD CAQKCQCDFN 
    NSLACDATNG RCVCKQDWGG VHCETNCRSG YYGENCDKVC RCLNNSSCDP DSGNCICSAG 
    WTGADCAEPC PPGFYGMECK ERCPEILHGN KSCDHITGEI LCRTGYIGLT CEHPCPAGLY 
    GPGCKLKCNC EHGGECNHVT GQCQCLPGWT GSNCNESCPT DTYGQGCAQR CRCVHHKVCR 
    KADGMCICET GWSGTRCDEV CPEGFYGEHC MNTCACPSAN FQCHAAHGCV CRSGYTGDNC 
    DELIASQRIA DQSENSSRAS VALTLVLMTL FACIIFAVFI YYRRRVSNLK TEIAHVHYTH 
    DTNPPSWPPN HNFDNPVYGM QAETRLLPNN MRSKMNNFDQ RSTMSTDYGD DCNASGRVGS 
    YSINYNHDLL TKNLNADRTN PIVYNESLKE EHVYDEIKHK EGYKDPVKIY SKILFPEDEY 
    DHLDYSRPST SQKPHYHRMN DAMLNINQDE EKPSNVKNMT VLLNKPLPPT EPEPQHECFD 
    NTNTNLDNVS TASPSSSPKF LK

Genular Protein ID: 1002791648

Symbol: M9PBI3_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 976
  • Mass: 106797
  • Checksum: 1009A03940BBA3FF
  • Sequence:
  • MLPVILIACL AQLVLAQADL KDLDGPNICK RRELYNVDVV YTELQSFQER GSTWCVTFPP 
    RCSTYRIKHR VVNKTKTIAK NRIVRDCCDG YIASAGECVP HCSEPCQHGR CISPEKCKCD 
    HGYGGPACDI NCPPGWYGRN CSMQCDCLNN AVCEPFSGDC ECAKGYTGAR CADICPEGFF 
    GANCSEKCRC ENGGKCHHVS GECQCAPGFT GPLCDMRCPD GKHGAQCQQD CPCQNDGKCQ 
    PETGACMCNP GWTGDVCANK CPVGSYGPGC QESCECYKGA PCHHITGQCE CPPGYRGERC 
    FDECQLNTYG FNCSMTCDCA NDAMCDRANG TCICNPGWTG AKCAERICEA NKYGLDCNRT 
    CECDMEHTDL CHPETGNCQC SIGWSSAQCT RPCTFLRYGP NCELTCNCKN GAKCSPVNGT 
    CLCAPGWRGP TCEESCEPGT FGQDCALRCD CQNGAKCEPE TGQCLCTAGW KNIKCDRPCD 
    LNHFGQDCAK VCDCHNNAAC NPQNGSCTCA AGWTGERCER KCDTGKFGHD CAQKCQCDFN 
    NSLACDATNG RCVCKQDWGG VHCETNCRSG YYGENCDKVC RCLNNSSCDP DSGNCICSAG 
    WTGADCAEPC PPGFYGMECK ERCPEILHGN KSCDHITGEI LCRTGYIGLT CEHPCPAGLY 
    GPGCKLKCNC EHGGECNHVT GQCQCLPGWT GSNCNESCPT DTYGQGCAQR CRCVHHKVCR 
    KADGMCICET GWSGTRCDEV CPEGFYGEHC MNTCACPSAN FQCHAAHGCV CRSGYTGDNC 
    DELIASQRIA DQSENSSRAS VALTLVLMTL FACIIFAVFI YYRRRVSNLK TEIAHVHYTH 
    DTNPPSWPPN HNFDNPVYGM QAETRLLPNN MRSKMNNFDQ RSTMSTDYGD DCNASGRVGS 
    YSINYNHDLL TKNLNADRTN PIVYNESLKE EHVYDEIKHK EGYKDPGMSL DFYTGRLSNF 
    TINYVLYICT HYGMNQ

Genular Protein ID: 3530252875

Symbol: M9PDW5_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 613
  • Mass: 68346
  • Checksum: DD77D3F0BD88023D
  • Sequence:
  • MLPVILIACL AQLVLAQADL KDLDGPNICK RRELYNVDVV YTELQSFQER GSTWCVTFPP 
    RCSTYRIKHR VVNKTKTIAK NRIVRDCCDG YIASAGECVP HCSEPCQHGR CISPEKCKCD 
    HGYGGPACDI SVHCETNCRS GYYGENCDKV CRCLNNSSCD PDSGNCICSA GWTGADCAEP 
    CPPGFYGMEC KERCPEILHG NKSCDHITGE ILCRTGYIGL TCEHPCPAGL YGPGCKLKCN 
    CEHGGECNHV TGQCQCLPGW TGSNCNESCP TDTYGQGCAQ RCRCVHHKVC RKADGMCICE 
    TGWSGTRCDE VCPEGFYGEH CMNTCACPSA NFQCHAAHGC VCRSGYTGDN CDELIASQRI 
    ADQSENSSRA SVALTLVLMT LFACIIFAVF IYYRRRVSNL KTEIAHVHYT HDTNPPSWPP 
    NHNFDNPVYG MQAETRLLPN NMRSKMNNFD QRSTMSTDYG DDCNASGRVG SYSINYNHDL 
    LTKNLNADRT NPIVYNESLK EEHVYDEIKH KEGYKDPVKI YSKILFPEDE YDHLDYSRPS 
    TSQKPHYHRM NDAMLNINQD EEKPSNVKNM TVLLNKPLPP TEPEPQHECF DNTNTNLDNV 
    STASPSSSPK FLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.