sty | FBgn0014388 | NCBI 38424

Details for: sty

Gene ID: 38424

Symbol: sty

Ensembl ID: FBgn0014388

Description: sprouty

Associated with

Egfr downregulation
(R-DME-182971)
Negative regulation of fgfr1 signaling
(R-DME-5654726)
Negative regulation of fgfr2 signaling
(R-DME-5654727)
Negative regulation of fgfr3 signaling
(R-DME-5654732)
Negative regulation of fgfr4 signaling
(R-DME-5654733)
Signaling by egfr
(R-DME-177929)
Signaling by fgfr
(R-DME-190236)
Signaling by fgfr1
(R-DME-5654736)
Signaling by fgfr2
(R-DME-5654738)
Signaling by fgfr3
(R-DME-5654741)
Signaling by fgfr4
(R-DME-5654743)
Signaling by receptor tyrosine kinases
(R-DME-9006934)
Signal transduction
(R-DME-162582)
Spry regulation of fgf signaling
(R-DME-1295596)
Animal organ development
(GO:0048513)
Apical part of cell
(GO:0045177)
Branching involved in open tracheal system development
(GO:0060446)
Compound eye morphogenesis
(GO:0001745)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Dorsal/ventral axis specification, ovarian follicular epithelium
(GO:0008069)
Glial cell development
(GO:0021782)
Lamellocyte differentiation
(GO:0035171)
Membrane
(GO:0016020)
Muscle cell development
(GO:0055001)
Negative regulation of epidermal growth factor receptor signaling pathway
(GO:0042059)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of imaginal disc-derived wing vein specification
(GO:0110109)
Negative regulation of map kinase activity
(GO:0043407)
Negative regulation of photoreceptor cell differentiation
(GO:0046533)
Negative regulation of ras protein signal transduction
(GO:0046580)
Negative regulation of torso signaling pathway
(GO:0120177)
Ommatidial rotation
(GO:0016318)
Open tracheal system development
(GO:0007424)
Plasma membrane
(GO:0005886)
Regulation of compound eye photoreceptor development
(GO:0045314)
Regulation of signal transduction
(GO:0009966)
Response to hypoxia
(GO:0001666)

Other Information

Proteins

Protein sprouty

Genular Protein ID: 2458307430

Symbol: SPY_DROME

Name: Protein sprouty

UniProtKB Accession Codes:

O44783 A4V1F3 Q6AWR4 Q9VZP7

Database IDs:

Citations:

PubMed ID: 9458049

Title: Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

PubMed ID: 9458049

DOI: 10.1016/s0092-8674(00)80919-8

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10089881

Title: Sprouty, an intracellular inhibitor of Ras signaling.

PubMed ID: 10089881

DOI: 10.1016/s0092-8674(00)80576-0

PubMed ID: 10226010

Title: Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila.

PubMed ID: 10226010

DOI: 10.1242/dev.126.11.2515

PubMed ID: 10457022

Title: Sprouty is a general inhibitor of receptor tyrosine kinase signaling.

PubMed ID: 10457022

DOI: 10.1242/dev.126.18.4139

Sequence Information:

Length: 589
Mass: 62389
Checksum: 7450E11987B17B20
Sequence:

MDRRNGGDPL APPRPPKLLP RVHRPRAPEP TLSGVDHNAG ATASALASGA SSAAPVAIHN 
NNSQQQLSIS AAASNNNTIS IIPASPDFDD YQIHHLTFLP QRPSSLSRNS STASSTTATG 
ISVSGSGSVS GSSSSFTRRR PPAPVPLNNS ISNNNNNSIN NNFLSHFQSA EPASNALGQP 
PASPVTLAQP RPESERLTNE YVDTPLQHAT RSQHPAGQQD NGQTTTHHLL LLPQRNQHLH 
LQQHQQHLQQ QQQQQQQQQQ QQHLQHQQNQ QHARLATTTQ ATSVGSDHTD GLLHSHLQNS 
TTKPPASKQP APPRLGMGLG LGLGLGLNQP IITKQPTPAT QKERMHALEE LLQPGGAGGN 
GGPLVMAGDP SLLNPIVCPR CGRCRCEQCQ SPRPLPQTWV CNKTCLCSAE SVIDYASCLC 
CAKALFYHCA RDNDLDCDDG NGTPCVDNPC SCGPYKRTQR WGWLGALSIF LPCLWFYWPM 
RGCMKLCEKC YGRFAGRGCR CQGIGGGGAG SGGGVGSIGS TSSMLPIVPL GVNGSGLGGG 
VSLSGGVTDG GLNQANGKAM DHGCSAARSI LRKGDLTPEK RLLDSSPDY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: sty

Associated with

Other Information

Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. PubMed ID: 9458049

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

Sprouty, an intracellular inhibitor of Ras signaling. PubMed ID: 10089881

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. PubMed ID: 10226010