Details for: Ccz1

Gene ID: 38455

Symbol: Ccz1

Ensembl ID: FBgn0035470

Description: Caffeine, calcium, zinc sensitivity 1

Associated with

Other Information

Genular Protein ID: 3706111010

Symbol: CCZ1_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VZL5 Q8SYB1

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ComplexPortal 1 DNASU 1 EMBL 2 EMDB 2 EnsemblMetazoa 1 FlyBase 1 GO 7 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PaxDb 1 Pfam 3 Proteomes 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 23418349

Title: Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila.

PubMed ID: 23418349

DOI: 10.1242/jcs.114934

PubMed ID: 27559127

Title: The Ccz1-Mon1-Rab7 module and Rab5 control distinct steps of autophagy.

PubMed ID: 27559127

DOI: 10.1091/mbc.e16-03-0205

PubMed ID: 32391792

Title: A conserved and regulated mechanism drives endosomal Rab transition.

PubMed ID: 32391792

DOI: 10.7554/elife.56090

PubMed ID: 32499409

Title: A trimeric metazoan Rab7 GEF complex is crucial for endocytosis and scavenger function.

PubMed ID: 32499409

DOI: 10.1242/jcs.247080

PubMed ID: 37463208

Title: Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation.

PubMed ID: 37463208

DOI: 10.1073/pnas.2303750120

PubMed ID: 37155863

Title: Structure of the metazoan Rab7 GEF complex Mon1-Ccz1-Bulli.

PubMed ID: 37155863

DOI: 10.1073/pnas.2301908120

Sequence Information:

  • Length: 485
  • Mass: 55523
  • Checksum: 136CC96B672A5F61
  • Sequence:
    • MAKLLQRVEI TLRSFYIFNS TFGQVEGEEH KKVLFYHPND IELNTKIKDV GLSEAIIRFT 
GTFTSEDDCQ ALHTQKTTQL FYQPEPGYWL VLVLNVPKEV RLKEGVEVAD YRGAEISDRI 
YRAILRQCYQ MFRFQNGCFS SCGSEEPNPD KRRELLCQKL LQFYDQHLTN LRDPAQCDII 
DMLHSIQYLP LDKTLFLRAQ NFGTLCETFP DIKESIMLYQ EQVLCGGKLS PEDLHCVHSY 
VVQHVLKVEA SSSTIAVSPS LKRSISECQV GGFVRSRQKV AGDEHDAVNE EDHPMKVYVT 
LDKEAKPYYL LIYRALHITL CLFLNADQVA PKQDLYDDLH AYMAPQLTSL ARDISSELTK 
EAVGAAGQDN SSGNSETAPK YLFINEQSLQ HHTNFQRHLP QGLPRNVLSI IADLANGSGK 
AEMESAPAEE VQVKTTNDYW IVKRRCNYRQ YYVILCNSKA TLLDVTQEAR RIFEQELTDD 
VFFDK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.