Details for: Ack

Gene ID: 38489

Symbol: Ack

Ensembl ID: FBgn0028484

Description: Activated Cdc42 kinase

Associated with

Other Information

Genular Protein ID: 3538963113

Symbol: ACK_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11773052

Title: Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance.

PubMed ID: 11773052

DOI: 10.1074/jbc.m110172200

PubMed ID: 11997505

Title: ACK family tyrosine kinase activity is a component of Dcdc42 signaling during dorsal closure in Drosophila melanogaster.

PubMed ID: 11997505

DOI: 10.1128/mcb.22.11.3685-3697.2002

PubMed ID: 18816840

Title: Leading edge-secreted Dpp cooperates with ACK-dependent signaling from the amnioserosa to regulate myosin levels during dorsal closure.

PubMed ID: 18816840

DOI: 10.1002/dvdy.21722

PubMed ID: 22615583

Title: Drosophila activated Cdc42 kinase has an anti-apoptotic function.

PubMed ID: 22615583

DOI: 10.1371/journal.pgen.1002725

PubMed ID: 23562806

Title: Activated Cdc42 kinase regulates Dock localization in male germ cells during Drosophila spermatogenesis.

PubMed ID: 23562806

DOI: 10.1016/j.ydbio.2013.02.025

PubMed ID: 23579691

Title: Modulation of morphogenesis by Egfr during dorsal closure in Drosophila.

PubMed ID: 23579691

DOI: 10.1371/journal.pone.0060180

PubMed ID: 25223282

Title: Ack kinase regulates CTP synthase filaments during Drosophila oogenesis.

PubMed ID: 25223282

DOI: 10.15252/embr.201438688

PubMed ID: 27462444

Title: Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.

PubMed ID: 27462444

DOI: 10.1038/celldisc.2015.47

Sequence Information:

  • Length: 1073
  • Mass: 118418
  • Checksum: D9BF4BD87235D691
  • Sequence:
  • MTSTSAVDGG LGSETAWLED LLREVQLEQF LDRIRDDLQV TRLAHFDYVL PDDLERCGLG 
    KPAIRRLMEA VRKKKAHQWR KNILSKLIGG GKQPSSKKQS SAARESSQGN GTQLTCLIHE 
    KDITMGLKLG DGSFGVVRRG EWSASPAGKV IPVAVKVLKS DNLTQPGIID DFFREVQAMH 
    ALDHANLVRL YGVVLSQPMM MITELAERGS LLDTLRKQCR HTSLTIIWNW SVQIVTGMAY 
    LEQKRFLHRD LACRNVLLAA GNKIKIGDFG LMRALPQEDD CYVMSEHKKV PFPWCAPESL 
    RFRQFSHASD TWMFGVTLWE MFSFGEDPWV GLNGSQILRK IDREGERLHQ PDACPPDVYA 
    MMLQCWDKTP AERPTFAALK EYLASMSPPV MRASRSHHES KGLQIEPGDT IAIIDGRHEL 
    KLIKGQNQRT FDIGIFPRNL LEQRKVGAAG DVVMRSSVGN GSSSSPFGFC WGGAAAMANG 
    DDRQRKCASM TNQPHAKERK STSSKQFAYN KLVNDSATGL QRRNAVKHKG VVVGPQRPPP 
    PQFQQEGILI DISPDMRPIA EAGTGGAKGA GDSSSLQADS SFCILDAPID VPTYAGSSGS 
    GDLNVSPTYY NEQPQFDFDP AKMTASPGRL QPPPYQMPPT YSNTMEFVQK RDLHQQQLAT 
    PVRERDPFDT TNVETTVALY SNFNQSLEAA SPPAPIYNSP SVRKSLFGGS KSNKENIPAL 
    ESAAMQLNLS NLTLERHDAT CIQPVEPVPA PPGDGVLLDK SFIAELEKDM YSNGQNRAQE 
    EYQRNSTQMY ASKDMVYKQN LTPLKNGAAP GSVHSNHSSP SSTASPKQNN VEAAAAAAAT 
    TQSVVNRIWY EQVASTQSEY YAQPPTEQAE EQIYQNHRHQ QQQQQELNHS FVAISNRVVA 
    PKNNAYSSTA SLYDAVAAST AGSTYYGQVP NGSGAVLYDE VTQDDYLRPT RPAPLAPPPL 
    SAQQIQRRME KMRLQQQQQL DGAHQLYAPV PSDYGREQEK LQQLMQELGS SAVEQDVRNA 
    LRAASGDVGL ATRHYKIDQL ARLGVAGRPQ CEQALQQTNW SLEVAAELLL NAG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.