Details for: nAChRbeta1

Gene ID: 38545

Symbol: nAChRbeta1

Ensembl ID: FBgn0000038

Description: nicotinic Acetylcholine Receptor beta1

Associated with

  • Acetylcholine binding and downstream events
    (R-DME-181431)
  • Highly calcium permeable nicotinic acetylcholine receptors
    (R-DME-629597)
  • Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
    (R-DME-629594)
  • Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
    (R-DME-629587)
  • Immune system
    (R-DME-168256)
  • Innate immune system
    (R-DME-168249)
  • Neuronal system
    (R-DME-112316)
  • Neurotransmitter receptors and postsynaptic signal transmission
    (R-DME-112314)
  • Neutrophil degranulation
    (R-DME-6798695)
  • Postsynaptic nicotinic acetylcholine receptors
    (R-DME-622327)
  • Presynaptic nicotinic acetylcholine receptors
    (R-DME-622323)
  • Transmission across chemical synapses
    (R-DME-112315)
  • Acetylcholine-gated channel complex
    (GO:0005892)
  • Acetylcholine-gated monoatomic cation-selective channel activity
    (GO:0022848)
  • Chemical synaptic transmission
    (GO:0007268)
  • Excitatory extracellular ligand-gated monoatomic ion channel activity
    (GO:0005231)
  • Monoatomic ion transmembrane transport
    (GO:0034220)
  • Neuron projection
    (GO:0043005)
  • Plasma membrane
    (GO:0005886)
  • Postsynaptic membrane
    (GO:0045211)
  • Regulation of membrane potential
    (GO:0042391)
  • Synapse
    (GO:0045202)
  • Synaptic transmission, cholinergic
    (GO:0007271)
  • Transmembrane signaling receptor activity
    (GO:0004888)
  • Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
    (GO:1904315)

Other Information

Genular Protein ID: 2517757842

Symbol: ACH3_DROME

Name: Acetylcholine receptor subunit beta-like 1

UniProtKB Accession Codes:

P04755 Q9VZC3

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DNASU 1 EMBL 6 ExpressionAtlas 1 FlyBase 1 GO 10 Gene3D 2 GenomeRNAi 1 GlyCosmos 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 4 RefSeq 1 SMR 1 STRING 1 SUPFAM 2 eggNOG 1

Citations:

PubMed ID: 16453690

Title: Primary structure of a developmentally regulated nicotinic acetylcholine receptor protein from Drosophila.

PubMed ID: 16453690

DOI: 10.1002/j.1460-2075.1986.tb04389.x

PubMed ID: 3136037

Title: Characterization of an invertebrate nicotinic acetylcholine receptor gene: the ard gene of Drosophila melanogaster.

PubMed ID: 3136037

DOI: 10.1016/0014-5793(88)81230-4

PubMed ID: 2832736

Title: Expression of a Drosophila melanogaster acetylcholine receptor-related gene in the central nervous system.

PubMed ID: 2832736

DOI: 10.1128/mcb.8.2.778-785.1988

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

Sequence Information:

  • Length: 521
  • Mass: 59902
  • Checksum: FF9BA2ABC0C3AA62
  • Sequence:
    • MESSCKSWLL CSILVLVAFS LVSASEDEER LVRDLFRGYN KLIRPVQNMT QKVGVRFGLA 
FVQLINVNEK NQVMKSNVWL RLVWYDYQLQ WDEADYGGIG VLRLPPDKVW KPDIVLFNNA 
DGNYEVRYKS NVLIYPTGEV LWVPPAIYQS SCTIDVTYFP FDQQTCIMKF GSWTFNGDQV 
SLALYNNKNF VDLSDYWKSG TWDIIEVPAY LNVYEGDSNH PTETDITFYI IIRRKTLFYT 
VNLILPTVLI SFLCVLVFYL PAEAGEKVTL GISILLSLVV FLLLVSKILP PTSLVLPLIA 
KYLLFTFIMN TVSILVTVII INWNFRGPRT HRMPMYIRSI FLHYLPAFLF MKRPRKTRLR 
WMMEMPGMSM PAHPHPSYGS PAELPKHISA IGGKQSKMEV MELSDLHHPN CKINRKVNSG 
GELGLGDGCR RESESSDSIL LSPEASKATE AVEFIAEHLR NEDLYIQTRE DWKYVAMVID 
RLQLYIFFIV TTAGTVGILM DAPHIFEYVD QDRIIEIYRG K

Genular Protein ID: 2508739653

Symbol: Q9VZC4_DROME

Name: N/A

UniProtKB Accession Codes:

Q9VZC4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 1 GeneTree 1 HOGENOM 1 NCBI Taxonomy 1 OrthoDB 1 Proteomes 2 RefSeq 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 64
  • Mass: 7213
  • Checksum: 454763992E76B996
  • Sequence:
    • MESSCKSWLL CSILVLVAFS LGTYFGLRRR RLPRPLSGKG RYVIVKERNA NEGLKTLLTL 
LTVS

Genular Protein ID: 2877750471

Symbol: E8NHB5_DROME

Name: N/A

UniProtKB Accession Codes:

E8NHB5

Database IDs:

ARBA 18 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HOGENOM 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 Pfam 4 PhylomeDB 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 2 VEuPathDB 1

Sequence Information:

  • Length: 521
  • Mass: 59916
  • Checksum: 7BBD430D64A08E44
  • Sequence:
    • MESSCKSWLL CSILVLVAFS LVSASEDEER LVRDLFRGYN KLIRPVQNMT QKVGVRFGLA 
FVQLINVNEK NQIMKSNVWL RLVWYDYQLQ WDEADYGGIG VLRLPPDKVW KPDIVLFNNA 
DGNYEVRYKS NVLIYPTGEV LWVPPAIYQS SCTIDVTYFP FDQQTCIMKF GSWTFNGDQV 
SLALYNNKNF VDLSDYWKSG TWDIIEVPAY LNVYEGDSNH PTETDITFYI IIRRKTLFYT 
VNLILPTVLI SFLCVLVFYL PAEAGEKVTL GISILLSLVV FLLLVSKILP PTSLVLPLIA 
KYLLFTFIMN TVSILVTVII INWNFRGPRT HRMPMYIRSI FLHYLPAFLF MKRPRKTRLR 
WMMEMPGMSM PAHPHPSYGS PAELPKHISA IGGKQSKMEV MELSDLHHPN CKINRKVNSG 
GELGLGDGCR RESESSDSIL LSPEASKATE AVEFIAEHLR NEDLYIQTRE DWKYVAMVID 
RLQLYIFFIV TTAGTVGILM DAPHIFEYVD QDRIIEIYRG K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.