Details for: RHOA
Associated with
Other Information
Genular Protein ID: 1018258098
Symbol: RHOA_HUMAN
Name: Rho cDNA clone 12
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3822842
Title: Nucleotide sequence of human rho cDNA clone 12.
PubMed ID: 3822842
PubMed ID: 7835413
Title: Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.
PubMed ID: 7835413
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8039707
Title: Utilization of multiple polyadenylation signals in the human RHOA protooncogene.
PubMed ID: 8039707
PubMed ID: 1328215
Title: A rho gene product in human blood platelets. I. Identification of the platelet substrate for botulinum C3 ADP-ribosyltransferase as rhoA protein.
PubMed ID: 1328215
PubMed ID: 7777059
Title: Glucosylation of Rho proteins by Clostridium difficile toxin B.
PubMed ID: 7777059
DOI: 10.1038/375500a0
PubMed ID: 1556108
Title: Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1).
PubMed ID: 1556108
PubMed ID: 7775453
Title: The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins.
PubMed ID: 7775453
PubMed ID: 8617235
Title: The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.
PubMed ID: 8617235
PubMed ID: 8641286
Title: Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.
PubMed ID: 8641286
PubMed ID: 8910519
Title: Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling.
PubMed ID: 8910519
PubMed ID: 8810274
Title: Clostridium novyi alpha-toxin-catalyzed incorporation of GlcNAc into Rho subfamily proteins.
PubMed ID: 8810274
PubMed ID: 9121475
Title: The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization.
PubMed ID: 9121475
PubMed ID: 9635436
Title: The small GTP-binding protein RhoA regulates a delayed rectifier potassium channel.
PubMed ID: 9635436
PubMed ID: 9857026
Title: Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases.
PubMed ID: 9857026
PubMed ID: 10066731
Title: Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA.
PubMed ID: 10066731
PubMed ID: 10438814
Title: RhoA interacts with the fusion glycoprotein of respiratory syncytial virus and facilitates virus-induced syncytium formation.
PubMed ID: 10438814
PubMed ID: 10940294
Title: The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element.
PubMed ID: 10940294
PubMed ID: 11162591
Title: cGMP-dependent protein kinase phosphorylates and inactivates RhoA.
PubMed ID: 11162591
PubMed ID: 11696353
Title: Ht31: the first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling.
PubMed ID: 11696353
PubMed ID: 12221096
Title: XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.
PubMed ID: 12221096
PubMed ID: 12062101
Title: A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis.
PubMed ID: 12062101
PubMed ID: 12551911
Title: Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.
PubMed ID: 12551911
PubMed ID: 12900402
Title: Direct activation of phospholipase C-epsilon by Rho.
PubMed ID: 12900402
PubMed ID: 12538863
Title: Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.
PubMed ID: 12538863
PubMed ID: 16103226
Title: An ECT2-centralspindlin complex regulates the localization and function of RhoA.
PubMed ID: 16103226
PubMed ID: 16236794
Title: Dissecting the role of Rho-mediated signaling in contractile ring formation.
PubMed ID: 16236794
PubMed ID: 17115030
Title: The armadillo protein p0071 regulates Rho signalling during cytokinesis.
PubMed ID: 17115030
DOI: 10.1038/ncb1504
PubMed ID: 19934221
Title: The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration.
PubMed ID: 19934221
DOI: 10.1242/jcs.053728
PubMed ID: 19403695
Title: Dual roles for RHOA/RHO-kinase in the regulated trafficking of a voltage-sensitive potassium channel.
PubMed ID: 19403695
PubMed ID: 19362538
Title: The fic domain: regulation of cell signaling by adenylylation.
PubMed ID: 19362538
PubMed ID: 19782033
Title: Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement.
PubMed ID: 19782033
PubMed ID: 19039103
Title: AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling.
PubMed ID: 19039103
PubMed ID: 19948726
Title: Activated Rac1 GTPase translocates protein phosphatase 5 to the cell membrane and stimulates phosphatase activity in vitro.
PubMed ID: 19948726
PubMed ID: 20709748
Title: Splice variants of SmgGDS control small GTPase prenylation and membrane localization.
PubMed ID: 20709748
PubMed ID: 20400958
Title: Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1.
PubMed ID: 20400958
DOI: 10.1038/ncb2049
PubMed ID: 20937854
Title: ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.
PubMed ID: 20937854
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21565175
Title: ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.
PubMed ID: 21565175
PubMed ID: 20499158
Title: RACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathway.
PubMed ID: 20499158
PubMed ID: 20974804
Title: The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells.
PubMed ID: 20974804
DOI: 10.1128/mcb.01001-10
PubMed ID: 23940119
Title: The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1.
PubMed ID: 23940119
PubMed ID: 23325789
Title: cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells.
PubMed ID: 23325789
PubMed ID: 24141704
Title: A bacterial toxin catalyzing tyrosine glycosylation of Rho and deamidation of Gq and Gi proteins.
PubMed ID: 24141704
DOI: 10.1038/nsmb.2688
PubMed ID: 23871831
Title: A new mechanism of RhoA ubiquitination and degradation: roles of SCF(FBXL19) E3 ligase and Erk2.
PubMed ID: 23871831
PubMed ID: 24905543
Title: Haemorrhagic toxin and lethal toxin from Clostridium sordellii strain vpi9048: molecular characterization and comparative analysis of substrate specificity of the large clostridial glucosylating toxins.
PubMed ID: 24905543
DOI: 10.1111/cmi.12321
PubMed ID: 25588844
Title: Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils.
PubMed ID: 25588844
DOI: 10.1242/jcs.161497
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27807006
Title: RHO binding to FAM65A regulates Golgi reorientation during cell migration.
PubMed ID: 27807006
DOI: 10.1242/jcs.198614
PubMed ID: 28630045
Title: Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.
PubMed ID: 28630045
PubMed ID: 31888991
Title: Structure and regulation of human epithelial cell transforming 2 protein.
PubMed ID: 31888991
PubMed ID: 31570889
Title: Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome.
PubMed ID: 31570889
PubMed ID: 30061757
Title: Nepsilon-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function.
PubMed ID: 30061757
PubMed ID: 9302995
Title: Crystal structure of RhoA-GDP and its functional implications.
PubMed ID: 9302995
DOI: 10.1038/nsb0997-699
PubMed ID: 9545299
Title: Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
PubMed ID: 9545299
PubMed ID: 10388627
Title: Biochemical and crystallographic characterization of a Rho effector domain of the protein serine/threonine kinase N in a complex with RhoA.
PubMed ID: 10388627
PubMed ID: 10748207
Title: An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
PubMed ID: 10748207
PubMed ID: 11927263
Title: MgF(3)(-) as a transition state analog of phosphoryl transfer.
PubMed ID: 11927263
PubMed ID: 12006984
Title: Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
PubMed ID: 12006984
DOI: 10.1038/nsb796
PubMed ID: 12777804
Title: Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution.
PubMed ID: 12777804
PubMed ID: 30190425
Title: GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
PubMed ID: 30190425
Sequence Information:
- Length: 193
- Mass: 21768
- Checksum: C4DA2DC31FF858BC
- Sequence:
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPVK PEEGRDMANR IGAFGYMECS AKTKDGVREV FEMATRAALQ ARRGKKKSGC LVL
Genular Protein ID: 1465812677
Symbol: Q9BVT0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 101
- Mass: 11523
- Checksum: 5067AD783510BA63
- Sequence:
ENIPEKWTPE VKHFCPNVPI ILVGNKKDLR NDEHTRRELA KMKQEPVKPE EGRDMANRIG AFGYMECSAK TKDGVREVFE MATRAALQAR RGKKKSGCLV L
Genular Protein ID: 5413297
Symbol: C9JX21_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 187
- Mass: 21164
- Checksum: FC5FBC55C61CFE2A
- Sequence:
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPHC VARLECCGTI LAQLQPPPPR FKRFPCLSLL SSWGYRRPLP HPGAGET
Genular Protein ID: 3535377301
Symbol: A0A7I2YQV1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
Sequence Information:
- Length: 109
- Mass: 11990
- Checksum: 855CA53882BC352B
- Sequence:
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQEPVKPEEG RDMANRIGAF GYMECSAKTK DGVREVFEMA TRAALQARRG KKKSGCLVL
Genular Protein ID: 2889228444
Symbol: C9JRM1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 90
- Mass: 9715
- Checksum: D149B6073D36E321
- Sequence:
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQKTSQKSGP QKSSISVPTC PSSWLGIRRI FGMMSTQGGS
Genular Protein ID: 1686133518
Symbol: B4DKN9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 173
- Mass: 19570
- Checksum: 32B8F0A4C2DB820D
- Sequence:
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRNDEHTRRE LAKMKQEPVK PEEGRDMANR IGAFGYMECS AKTKDGVREV FEMATRAALQ ARRGKKKSGC LVL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.