sgl | FBgn0261445 | NCBI 38760

Details for: sgl

Gene ID: 38760

Symbol: sgl

Ensembl ID: FBgn0261445

Description: sugarless

Associated with

Biological oxidations
(R-DME-211859)
Formation of the active cofactor, udp-glucuronate
(R-DME-173599)
Glucuronidation
(R-DME-156588)
Metabolism
(R-DME-1430728)
Phase ii - conjugation of compounds
(R-DME-156580)
Chondroitin sulfate biosynthetic process
(GO:0030206)
Cytoplasm
(GO:0005737)
Epithelial cell migration, open tracheal system
(GO:0007427)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Glycosaminoglycan biosynthetic process
(GO:0006024)
Heparan sulfate proteoglycan biosynthetic process
(GO:0015012)
Heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
(GO:0015014)
Mesoderm migration involved in gastrulation
(GO:0007509)
Nad binding
(GO:0051287)
Nucleus
(GO:0005634)
Segment polarity determination
(GO:0007367)
Udp-glucose 6-dehydrogenase activity
(GO:0003979)
Udp-glucuronate biosynthetic process
(GO:0006065)

Other Information

Proteins

UDP-glucose 6-dehydrogenase

Genular Protein ID: 3185646634

Symbol: UGDH_DROME

Name: UDP-glucose 6-dehydrogenase

UniProtKB Accession Codes:

O02373 O02647 Q9VRZ9

Database IDs:

Citations:

PubMed ID: 9217004

Title: Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling.

PubMed ID: 9217004

DOI: 10.1242/dev.124.13.2623

PubMed ID: 9342049

Title: The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis.

PubMed ID: 9342049

DOI: 10.1242/dev.124.18.3565

PubMed ID: 9272947

Title: Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila.

PubMed ID: 9272947

DOI: 10.1242/dev.124.16.3055

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

Sequence Information:

Length: 476
Mass: 52875
Checksum: 1450B9A0C802BBE7
Sequence:

MKVCCIGAGY VGGPTCAVMA LKCPDIVITL VDKSSERIAQ WNSDKLPIYE PGLDEVVKKC 
RNVNLFFSTD IETAIKEADL IFISVNTPTK TCGNGKGRAA DLKYVESAAR MIAEIAQSNK 
IVVEKSTVPV RAAESIMHIL RANQKPGIHY DILSNPEFLA EGTAINDLLN ADRVLIGGEE 
TPEGHQAVEK LSWIYEHWIP KQNILTTNTW SSELSKLAAN AFLAQRISSI NSLSAVCEAT 
GADVSEVARA VGLDSRIGSK FLQASVGFGG SCFQKDILNL IYICENLNLP EVAAYWQQVI 
DMNEYQKRRF SQKIIESLFN TVSDKRIAIL GFAFKKNTGD TRETAAITVC QTLLEEGAAL 
DIYDPKVEPE QIIDDLTHPS VTESPEKVKK AVQIHSDPYS AVRATHALVI CTEWDEFVDL 
DFKRIYQSMM KPAYIFDGRK ILDHERLQQI GFHVQTIGKK YQRTGLLRSW GIVPQL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: sgl

Associated with

Other Information

Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. PubMed ID: 9217004

The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. PubMed ID: 9342049

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. PubMed ID: 9272947

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572