Clk | FBgn0023076 | NCBI 38872

Details for: Clk

Gene ID: 38872

Symbol: Clk

Ensembl ID: FBgn0023076

Description: Clock

Associated with

Behavioral response to cocaine
(GO:0048148)
Chromatin binding
(GO:0003682)
Circadian regulation of gene expression
(GO:0032922)
Circadian regulation of heart rate
(GO:0003053)
Circadian rhythm
(GO:0007623)
Clock-bmal transcription complex
(GO:1990513)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Eclosion rhythm
(GO:0008062)
Entrainment of circadian clock
(GO:0009649)
Locomotor rhythm
(GO:0045475)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein heterodimerization activity
(GO:0046982)
Regulation of circadian sleep/wake cycle, sleep
(GO:0045187)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to light stimulus
(GO:0009416)
Response to temperature stimulus
(GO:0009266)
Rhythmic behavior
(GO:0007622)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Circadian locomoter output cycles protein kaput

Genular Protein ID: 3781712275

Symbol: CLOCK_DROME

Name: Circadian locomoter output cycles protein kaput

UniProtKB Accession Codes:

O61735 A4V1L9 A4V1M0 O76342 O77137 Q59E25 Q9VSB0

Database IDs:

Citations:

PubMed ID: 9630223

Title: A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless.

PubMed ID: 9630223

DOI: 10.1016/s0092-8674(00)81440-3

PubMed ID: 9742131

Title: Circadian regulation of a Drosophila homolog of the mammalian clock gene: PER and TIM function as positive regulators.

PubMed ID: 9742131

DOI: 10.1128/mcb.18.10.6142

PubMed ID: 9616122

Title: Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

PubMed ID: 9616122

DOI: 10.1126/science.280.5369.1599

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

Sequence Information:

Length: 1027
Mass: 116142
Checksum: B4AAC80DBF6F954B
Sequence:

MDDESDDKDD TKSFLCRKSR NLSEKKRRDQ FNSLVNDLSA LISTSSRKMD KSTVLKSTIA 
FLKNHNEATD RSKVFEIQQD WKPAFLSNDE YTHLMLESLD GFMMVFSSMG SIFYASESIT 
SQLGYLPQDL YNMTIYDLAY EMDHEALLNI FMNPTPVIEP RQTDISSSNQ ITFYTHLRRG 
GMEKVDANAY ELVKFVGYFR NDTNTSTGSS SEVSNGSNGQ PAVLPRIFQQ NPNAEVDKKL 
VFVGTGRVQN PQLIREMSII DPTSNEFTSK HSMEWKFLFL DHRAPPIIGY MPFEVLGTSG 
YDYYHFDDLD SIVACHEELR QTGEGKSCYY RFLTKGQQWI WLQTDYYVSY HQFNSKPDYV 
VCTHKVVSYA EVLKDSRKEG QKSGNSNSIT NNGSSKVIAS TGTSSKSASA TTTLRDFELS 
SQNLDSTLLG NSLASLGTET AATSPAVDSS PMWSASAVQP SGSCQINPLK TSRPASSYGN 
ISSTGISPKA KRKCYFYNNR GNDSDSTSMS TDSVTSRQSM MTHVSSQSQR QRSHHREHHR 
ENHHNQSHHH MQQQQQHQNQ QQQHQQHQQL QQQLQHTVGT PKMVPLLPIA STQIMAGNAC 
QFPQPAYPLA SPQLVAPTFL EPPQYLTAIP MQPVIAPFPV APVLSPLPVQ SQTDMLPDTV 
VMTPTQSQLQ DQLQRKHDEL QKLILQQQNE LRIVSEQLLL SRYTYLQPMM SMGFAPGNMT 
AAAVGNLGAS GQRGLNFTGS NAVQPQFNQY GFALNSEQML NQQDQQMMMQ QQQNLHTQHQ 
HNLQQQHQSH SQLQQHTQQQ HQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQLQLQQQ 
NDILLREDID DIDAFLNLSP LHSLGSQSTI NPFNSSSNNN NQSYNGGSNL NNGNQNNNNR 
SSNPPQNNNE DSLLSCMQMA TESSPSINFH MGISDDGSET QSEDNKMMHT SGSNLVQQQQ 
QQQQQQQILQ QHQQQSNSFF SSNPFLNSQN QNQNQLPNDL EILPYQMSQE QSQNLFNSPH 
TAPGSSQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Clk

Associated with

Other Information

A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless. PubMed ID: 9630223

Circadian regulation of a Drosophila homolog of the mammalian clock gene: PER and TIM function as positive regulators. PubMed ID: 9742131

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. PubMed ID: 9616122