Details for: MED24

Gene ID: 38914

Symbol: MED24

Ensembl ID: FBgn0035851

Description: Mediator complex subunit 24

Associated with

  • Epigenetic regulation by wdr5-containing histone modifying complexes
    (R-DME-9917777)
  • Epigenetic regulation of adipogenesis genes by mll3 and mll4 complexes
    (R-DME-9851695)
  • Epigenetic regulation of gene expression
    (R-DME-212165)
  • Epigenetic regulation of gene expression by mll3 and mll4 complexes
    (R-DME-9818564)
  • Gene expression (transcription)
    (R-DME-74160)
  • Mll4 and mll3 complexes regulate expression of pparg target genes in adipogenesis and hepatic steatosis
    (R-DME-9841922)
  • Autophagic cell death
    (GO:0048102)
  • Mediator complex
    (GO:0016592)
  • Nucleus
    (GO:0005634)
  • Positive regulation of programmed cell death
    (GO:0043068)
  • Positive regulation of transcription initiation by rna polymerase ii
    (GO:0060261)
  • Protein binding
    (GO:0005515)
  • Pupal development
    (GO:0035209)
  • Regulation of programmed cell death
    (GO:0043067)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to ecdysone
    (GO:0035075)
  • Salivary gland histolysis
    (GO:0035070)
  • Transcription coregulator activity
    (GO:0003712)

Other Information

Genular Protein ID: 2660108037

Symbol: MED24_DROME

Name: Mediator of RNA polymerase II transcription subunit 24

UniProtKB Accession Codes:

Q9VSF2 Q8MQZ3 Q9GYW5

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 FlyBase 1 GO 11 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RefSeq 1 SMR 1 STRING 1 SignaLink 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 12021283

Title: Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.

PubMed ID: 12021283

DOI: 10.1074/jbc.m204144200

PubMed ID: 16751183

Title: Coactivator cross-talk specifies transcriptional output.

PubMed ID: 16751183

DOI: 10.1101/gad.1418806

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

Sequence Information:

  • Length: 993
  • Mass: 111743
  • Checksum: 63146DB943200E7A
  • Sequence:
    • MKENNKILQL IYVAWRERWT DSQWGINIKK VLPRGVSGDV YNLADCLMQQ ALIGSTANPL 
VLNYLKHSLC AHLVSHAAVI RCIAKYDKLE RVYCITALLE FLASIVDGVT CRIKSEEAVL 
PSSVVHLVYW LLQIFARTVQ HYELYGEISA EQSYMLDQTC VVIDRLSQQQ FLLSMLYVGC 
HEELEICGRI RDKYATIKGS LTNSNFTLNA PQVEQQLQQL AFIEAKHLEM QPLNPPSTLE 
KISCCVQPLL AVEVLLNPCK DTSYYVAELQ MLQRLKKYSN TRLFYEIIRA GFLTLSNVAD 
TSPDTMWGAF MFFKMPHIIK QLHALQRIPG EQPPPADYIP ELVEALELLI EDNLLLDFMD 
TKCSCNMIEF LLNDWTKQQL VNDVHVKKFA SQREAASQLL KKCDNGQQTP SNINFIKRAE 
VPLSGVLKTL CTNKVQDMVN VLCQVPVGNS FELILSVATV EGRLKTFVSR LIQCNENSKP 
VPGDLGKLCV IRSTLFDVSF LMLTSIVQTY GSDVVLSERG DSFFEKWVRE CMVERNKLKN 
PRQILALCDD SIVDELLLSF SKPEASQLKP NNLSWQETCL NLPGVLHHVL IAWEQETLSS 
ADVKSILDNI KRRLFSFSVC ATSFLCAYMY SVKETELLKP LNMIQQFLAP LTSEELSSQE 
NAKERLALSY QIIRKMQHDV HPAPSTKSRL ISHSPLVEQF REVWRTVVDA GHLPVRAAQS 
LESLLLAGGA AWLSTQLVEQ LLACKYTRDM SRTMDVVFAV MHLDIEKTTE ALLQYVVAPL 
ILRRQGEDIN EPQSLVLARL CVYCIISCLE SRKGNGTSAL TAMKKRSRSH DDEELAANAA 
KVRKVIGDGS DNSSDFTDTT TGAGLAALLG STSTSELRTT PLTLREPLQT SVQHIFAVFL 
QFVSGDELSP KAVFVYQFIS LLVECGGERV APVLRLLPNG LVQQLLKVLV TDDIKVGLIS 
RLYDLRIQAG RLSAVSDLCL WRNMQMARHS IHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.