Details for: nwk

Gene ID: 39052

Symbol: nwk

Ensembl ID: FBgn0263456

Description: nervous wreck

Associated with

Other Information

Genular Protein ID: 3436836398

Symbol: NWK_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 14980202

Title: Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila.

PubMed ID: 14980202

DOI: 10.1016/s0896-6273(04)00016-9

PubMed ID: 18701694

Title: Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.

PubMed ID: 18701694

DOI: 10.1523/jneurosci.2304-08.2008

PubMed ID: 18498733

Title: Nervous wreck interacts with thickveins and the endocytic machinery to attenuate retrograde BMP signaling during synaptic growth.

PubMed ID: 18498733

DOI: 10.1016/j.neuron.2008.03.007

PubMed ID: 21464232

Title: A presynaptic endosomal trafficking pathway controls synaptic growth signaling.

PubMed ID: 21464232

DOI: 10.1083/jcb.201009052

PubMed ID: 23761074

Title: Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck.

PubMed ID: 23761074

DOI: 10.1091/mbc.e13-05-0271

PubMed ID: 26686642

Title: Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation.

PubMed ID: 26686642

DOI: 10.1016/j.celrep.2015.11.044

PubMed ID: 26567222

Title: BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission.

PubMed ID: 26567222

DOI: 10.1242/jcs.178699

PubMed ID: 27601635

Title: Coordinated autoinhibition of F-BAR domain membrane binding and WASp activation by Nervous Wreck.

PubMed ID: 27601635

DOI: 10.1073/pnas.1524412113

PubMed ID: 29568072

Title: Regulation of synaptic architecture and synaptic vesicle pools by Nervous wreck at Drosophila Type 1b glutamatergic synapses.

PubMed ID: 29568072

DOI: 10.1038/emm.2017.303

Sequence Information:

  • Length: 1075
  • Mass: 117255
  • Checksum: A3AC3F8BE5A890FC
  • Sequence:
  • MQPPPRKGNY VKFLKNLHTE QVAKLQLKNQ HECDLLEDIR QFTIKRSAVE KSYSESLLKI 
    SSQYLNKKIP NIPDIKMEGM EERWNMWSVW RTVLEENEKL ARARLAAIEV FQQQIADEAK 
    VLRDYKLAIA KRSLAGIVNV QKELHLSVGD VDKTKKSYFD EEHCAHDVRD KARDIEEKLK 
    KKKGSFFQSI TSLQKNSARV TSRKELLEEK SSGARNDYVL SLAAANAHQN RYFTVDLQTT 
    MTTMENYVFE RVAEYLMLMG RTELLTCSAT QNSFGKIRDQ AQQLTREYNL QCCYLFYPVL 
    KQHIQYDFEA CDNDPVRKVT AEHESAAETL TKEAKNLAGR VVKENASIRE NAKKLALCQS 
    LRDSGQRTDP NDPNGPDLDT KIEEFRDQIR RSETEKTKAE ACLQCLRDGG INVDEWVQEA 
    ENMGVQELTR SASSISMRTD ASGQGENPSS DSFYDSDKEE TQAAAQTKPK QEQQLSRDRT 
    FSDSEDEPEV RPSAAAASSA AAASSSMMAS SAGGWDDPTE VNWGAGEEED DKDEPIVPEP 
    KEAIFKCTAL YSYTAQNPDE LTIVENEQLE VVGEGDGDGW LRARNYRGEE GYVPHNYLDI 
    DQETAGSAFN GTSGNQLRSQ ISFSSVDYTV DNEDQTVDSM QSPDQVSVIM APQKRVKSDV 
    EWCIALYDYD ATAEDELTFE EGDKIKIITK TAHGVDDGWW EGELDGKFGN FPSLVVEECD 
    EMGEPLSEGG DESPPPTAAP TFALPPAPAL PPEYAHELEL ELTEDMFGSQ DTADEDSGYI 
    PNGAAAPSIP PPVLIQEPGM EDDLSDDGQP PPSLPPPQLA KAGGSAPGSG SKVEKGAAAG 
    GANTLNLGMA QIIVTAATPM VEDGADKSFP PVGESDAQPV EPVSKEQPAE VAKKPDIAPK 
    PLAKVAPQSA PAKEGNAGVR PVVSITLTEY PSCDAEDQQS FSEGTDSASV ADVPVLQDAE 
    DPFNEKAKGE SGDGSGFEAN FEANFDANFD DAFAGIGGGG GGGGGGGEQS NELDINGEAA 
    GEAIVSGSAA GDEDIEAPKQ VVGGRASIPE ELDSNQLAHY HEHEIYYVDY SHGQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.