Dronc | FBgn0026404 | NCBI 39173

Details for: Dronc

Gene ID: 39173

Symbol: Dronc

Ensembl ID: FBgn0026404

Description: Death regulator Nedd2-like caspase

Associated with

Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Rna polymerase ii transcription
(R-DME-73857)
Tp53 regulates transcription of caspase activators and caspases
(R-DME-6803207)
Tp53 regulates transcription of cell death genes
(R-DME-5633008)
Transcriptional regulation by tp53
(R-DME-3700989)
Apoptosome
(GO:0043293)
Apoptotic process
(GO:0006915)
Card domain binding
(GO:0050700)
Central nervous system development
(GO:0007417)
Chaeta development
(GO:0022416)
Compound eye development
(GO:0048749)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type endopeptidase activity involved in apoptotic process
(GO:0097153)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway
(GO:0097199)
Cytoplasm
(GO:0005737)
Dendrite morphogenesis
(GO:0048813)
Determination of adult lifespan
(GO:0008340)
Ectopic germ cell programmed cell death
(GO:0035234)
Embryonic development via the syncytial blastoderm
(GO:0001700)
Endopeptidase activity
(GO:0004175)
Head involution
(GO:0008258)
Hemocyte development
(GO:0007516)
Melanization defense response
(GO:0035006)
Metamorphosis
(GO:0007552)
Negative regulation of cell population proliferation
(GO:0008285)
Neuron remodeling
(GO:0016322)
Nucleus
(GO:0005634)
Nurse cell apoptotic process
(GO:0045476)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of compound eye retinal cell programmed cell death
(GO:0046672)
Programmed cell death
(GO:0012501)
Programmed cell death involved in cell development
(GO:0010623)
Programmed necrotic cell death
(GO:0097300)
Protein autoprocessing
(GO:0016540)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Proteolysis
(GO:0006508)
Salivary gland histolysis
(GO:0035070)
Sperm individualization
(GO:0007291)
Zymogen activation
(GO:0031638)

Other Information

Proteins

Caspase Dronc

Genular Protein ID: 1975784105

Symbol: DRONC_DROME

Name: Caspase Dronc

UniProtKB Accession Codes:

Q9XYF4

Database IDs:

Citations:

PubMed ID: 10200258

Title: DRONC, an ecdysone-inducible Drosophila caspase.

PubMed ID: 10200258

DOI: 10.1073/pnas.96.8.4307

PubMed ID: 10675329

Title: The Drosophila caspase DRONC is regulated by DIAP1.

PubMed ID: 10675329

DOI: 10.1093/emboj/19.4.598

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 10984473

Title: An essential role for the caspase dronc in developmentally programmed cell death in Drosophila.

PubMed ID: 10984473

DOI: 10.1074/jbc.m002935200

PubMed ID: 12021771

Title: The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis.

PubMed ID: 12021771

DOI: 10.1038/ncb799

PubMed ID: 14517550

Title: Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination.

PubMed ID: 14517550

DOI: 10.1038/nsb989

Sequence Information:

Length: 450
Mass: 51141
Checksum: 640A9725202A7E65
Sequence:

MQPPELEIGM PKRHREHIRK NLNILVEWTN YERLAMECVQ QGILTVQMLR NTQDLNGKPF 
NMDEKDVRVE QHRRLLLKIT QRGPTAYNLL INALRNINCL DAAVLLESVD ESDSRPPFIS 
LNERRTSRKS ADIVDTPSPE ASEGPCVSKL RNEPLGALTP YVGVVDGPEV KKSKKIHGGD 
SAILGTYKMQ SRFNRGVLLM VNIMDYPDQN RRRIGAEKDS KSLIHLFQEL NFTIFPYGNV 
NQDQFFKLLT MVTSSSYVQN TECFVMVLMT HGNSVEGKEK VEFCDGSVVD MQKIKDHFQT 
AKCPYLVNKP KVLMFPFCRG DEYDLGHPKN QGNLMEPVYT AQEEKWPDTQ TEGIPSPSTN 
VPSLADTLVC YANTPGYVTH RDLDTGSWYI QKFCQVMADH AHDTDLEDIL KKTSEAVGNK 
RTKKGSMQTG AYDNLGFNKK LYFNPGFFNE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dronc

Associated with

Other Information

DRONC, an ecdysone-inducible Drosophila caspase. PubMed ID: 10200258

The Drosophila caspase DRONC is regulated by DIAP1. PubMed ID: 10675329

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

An essential role for the caspase dronc in developmentally programmed cell death in Drosophila. PubMed ID: 10984473

The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. PubMed ID: 12021771

Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. PubMed ID: 14517550