Details for: wls

Gene ID: 39259

Symbol: wls

Ensembl ID: FBgn0036141

Description: wntless

Associated with

Other Information

Genular Protein ID: 1407501898

Symbol: WLS_DROME

Name: N/A

UniProtKB Accession Codes:

Q95ST2 Q9VTG4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 7 EnsemblMetazoa 2 FlyBase 1 GO 31 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SignaLink 1 TCDB 1 UCSC 2 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 16678095

Title: Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.

PubMed ID: 16678095

DOI: 10.1016/j.cell.2006.02.049

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 16678096

Title: Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.

PubMed ID: 16678096

DOI: 10.1016/j.cell.2006.04.009

PubMed ID: 17108000

Title: Sprinter: a novel transmembrane protein required for Wg secretion and signaling.

PubMed ID: 17108000

DOI: 10.1242/dev.02674

PubMed ID: 18160348

Title: The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network.

PubMed ID: 18160348

DOI: 10.1016/j.devcel.2007.12.003

PubMed ID: 18193037

Title: Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

PubMed ID: 18193037

DOI: 10.1038/ncb1678

PubMed ID: 18193032

Title: Wingless secretion promotes and requires retromer-dependent cycling of Wntless.

PubMed ID: 18193032

DOI: 10.1038/ncb1687

PubMed ID: 19837038

Title: Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless.

PubMed ID: 19837038

DOI: 10.1016/j.cell.2009.07.051

Sequence Information:

  • Length: 594
  • Mass: 67890
  • Checksum: D8401B3C5D41E069
  • Sequence:
    • MSGTILENLS GRKLSILVAT LLLCQVLCFL LGGLYAPLPA GHVTVLGSLC REDHARQNDT 
SFLLYSRGAG ACIPVTREEV EQDSTKMANE LVHVFQMPLP RDLRDLDYSR WQQNLIGVLQ 
VEFGYDSSSE LREPPRELQL TIDMRLAYRN KGDPDNGWKL YAHGVEHRYL DCVTSHVGPT 
ETLYSCDMIP LFELGALHHS FYLLNLRFPL DTPSQMNLQF GHMHDLTLTA IHQNGGFTQI 
WLLLKTMLFP FVVGIMIWFW RRVHLLQRSP ALLEYMLIYL GAALTFLNLP LEYLSLVYEM 
PYMLLLSDIR QGIFYAMLLT FWLVFAGEHM LIQDAPNKST IRSRYWKHLS AVVVGCISLF 
VFDICERGVQ LRNPFYSIWT TPLGAKVAMT FIVLAGVSAA IYFLFLCYMI WKVFRNIGDK 
RTSLPSMSQA RRLHYEVPLD QKVEDWAGIV YFYTKAFFFQ LHKANESKGL IYRFKFLMLA 
TLVCAALTVA GFIMGQMAEG QWDWNDNVAI QPTSAFLTGV YGMWNIYIFA LLILYAPSHK 
QWPTMHHSDE TTQSNENIVA SAASEEIEFS HLPSDSNPSE ISSLTSFTRK VAFD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.