Details for: RpS12

Gene ID: 39480

Symbol: RpS12

Ensembl ID: FBgn0286213

Description: Ribosomal protein S12

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-DME-72662)
  • Cap-dependent translation initiation
    (R-DME-72737)
  • Eukaryotic translation initiation
    (R-DME-72613)
  • Formation of a pool of free 40s subunits
    (R-DME-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-DME-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-DME-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-DME-156827)
  • Metabolism of proteins
    (R-DME-392499)
  • Metabolism of rna
    (R-DME-8953854)
  • Nonsense-mediated decay (nmd)
    (R-DME-927802)
  • Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
    (R-DME-975957)
  • Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
    (R-DME-975956)
  • Ribosomal scanning and start codon recognition
    (R-DME-72702)
  • Srp-dependent cotranslational protein targeting to membrane
    (R-DME-1799339)
  • Translation initiation complex formation
    (R-DME-72649)
  • Cytoplasmic translation
    (GO:0002181)
  • Cytosolic ribosome
    (GO:0022626)
  • Cytosolic small ribosomal subunit
    (GO:0022627)
  • Maintenance of translational fidelity
    (GO:1990145)
  • Positive regulation of canonical wnt signaling pathway
    (GO:0090263)
  • Ribosomal small subunit biogenesis
    (GO:0042274)
  • Ribosome
    (GO:0005840)
  • Small-subunit processome
    (GO:0032040)
  • Structural constituent of ribosome
    (GO:0003735)
  • Translation
    (GO:0006412)

Other Information

Genular Protein ID: 3515770992

Symbol: RS12_DROME

Name: 40S ribosomal protein S12

UniProtKB Accession Codes:

P80455 Q0E8F1 Q9VU40

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EMDB 3 EnsemblMetazoa 1 FlyBase 2 GO 8 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 Reactome 9 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 31841522

Title: Drosophila RpS12 controls translation, growth, and cell competition through Xrp1.

PubMed ID: 31841522

DOI: 10.1371/journal.pgen.1008513

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

Sequence Information:

  • Length: 139
  • Mass: 15169
  • Checksum: 4810D50ADC87C253
  • Sequence:
    • MADVDVDVPS AAPVLDGAMD INTALQEVLK KSLIADGLVH GIHQACKALD KRQAVLCILA 
ESFDEPNYKK LVTALCNEHQ IPLIRVDSHK KLGEWSGLCK IDKEGKPRKV CGCSVVVIKD 
FGEETPALDV VKDHLRQNS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.