btl | FBgn0285896 | NCBI 39564

Details for: btl

Gene ID: 39564

Symbol: btl

Ensembl ID: FBgn0285896

Description: breathless

Associated with

Betaklotho-mediated ligand binding
(R-DME-1307965)
Downstream signaling of activated fgfr1
(R-DME-5654687)
Downstream signaling of activated fgfr2
(R-DME-5654696)
Downstream signaling of activated fgfr3
(R-DME-5654708)
Downstream signaling of activated fgfr4
(R-DME-5654716)
Fgfr1 ligand binding and activation
(R-DME-190242)
Fgfr1b ligand binding and activation
(R-DME-190370)
Fgfr1c and klotho ligand binding and activation
(R-DME-190374)
Fgfr1c ligand binding and activation
(R-DME-190373)
Fgfr2 ligand binding and activation
(R-DME-190241)
Fgfr2b ligand binding and activation
(R-DME-190377)
Fgfr2c ligand binding and activation
(R-DME-190375)
Fgfr3 ligand binding and activation
(R-DME-190239)
Fgfr3b ligand binding and activation
(R-DME-190371)
Fgfr3c ligand binding and activation
(R-DME-190372)
Fgfr4 ligand binding and activation
(R-DME-190322)
Frs-mediated fgfr1 signaling
(R-DME-5654693)
Frs-mediated fgfr2 signaling
(R-DME-5654700)
Frs-mediated fgfr3 signaling
(R-DME-5654706)
Frs-mediated fgfr4 signaling
(R-DME-5654712)
Igf1r signaling cascade
(R-DME-2428924)
Insulin receptor signalling cascade
(R-DME-74751)
Intracellular signaling by second messengers
(R-DME-9006925)
Irs-mediated signalling
(R-DME-112399)
Irs-related events triggered by igf1r
(R-DME-2428928)
Mapk1/mapk3 signaling
(R-DME-5684996)
Mapk family signaling cascades
(R-DME-5683057)
Negative regulation of fgfr1 signaling
(R-DME-5654726)
Negative regulation of fgfr2 signaling
(R-DME-5654727)
Negative regulation of fgfr3 signaling
(R-DME-5654732)
Negative regulation of fgfr4 signaling
(R-DME-5654733)
Negative regulation of the pi3k/akt network
(R-DME-199418)
Phospholipase c-mediated cascade: fgfr1
(R-DME-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-DME-5654221)
Phospholipase c-mediated cascade; fgfr3
(R-DME-5654227)
Phospholipase c-mediated cascade; fgfr4
(R-DME-5654228)
Pi-3k cascade:fgfr1
(R-DME-5654689)
Pi-3k cascade:fgfr2
(R-DME-5654695)
Pi-3k cascade:fgfr3
(R-DME-5654710)
Pi-3k cascade:fgfr4
(R-DME-5654720)
Pi3k cascade
(R-DME-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-DME-6811558)
Pip3 activates akt signaling
(R-DME-1257604)
Raf/map kinase cascade
(R-DME-5673001)
Shc-mediated cascade:fgfr1
(R-DME-5654688)
Shc-mediated cascade:fgfr2
(R-DME-5654699)
Shc-mediated cascade:fgfr3
(R-DME-5654704)
Shc-mediated cascade:fgfr4
(R-DME-5654719)
Signaling by fgfr
(R-DME-190236)
Signaling by fgfr1
(R-DME-5654736)
Signaling by fgfr2
(R-DME-5654738)
Signaling by fgfr3
(R-DME-5654741)
Signaling by fgfr4
(R-DME-5654743)
Signaling by insulin receptor
(R-DME-74752)
Signaling by receptor tyrosine kinases
(R-DME-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-DME-2404192)
Signal transduction
(R-DME-162582)
Atp binding
(GO:0005524)
Border follicle cell migration
(GO:0007298)
Branch fusion, open tracheal system
(GO:0035147)
Branching involved in open tracheal system development
(GO:0060446)
Compound eye morphogenesis
(GO:0001745)
Epithelial cell migration, open tracheal system
(GO:0007427)
Epithelial cell type specification, open tracheal system
(GO:0035153)
Fibroblast growth factor receptor activity
(GO:0005007)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Filopodium assembly
(GO:0046847)
Genital disc development
(GO:0035215)
Glial cell migration
(GO:0008347)
Lumen formation, open tracheal system
(GO:0035149)
Multicellular organism development
(GO:0007275)
Negative regulation of axon extension
(GO:0030517)
Negative regulation of crystal cell differentiation
(GO:0042690)
Negative regulation of plasmatocyte differentiation
(GO:0045614)
Open tracheal system development
(GO:0007424)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of kinase activity
(GO:0033674)
Positive regulation of melanization defense response
(GO:0035008)
Positive regulation of synaptic assembly at neuromuscular junction
(GO:0045887)
Primary branching, open tracheal system
(GO:0007428)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein tyrosine kinase activity
(GO:0004713)
Secondary branching, open tracheal system
(GO:0007429)
Terminal branching, open tracheal system
(GO:0007430)
Terminal cell fate specification, open tracheal system
(GO:0035154)
Trachea development
(GO:0060438)
Tracheal outgrowth, open tracheal system
(GO:0007426)
Tracheal pit formation in open tracheal system
(GO:0035202)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)

Other Information

Proteins

Fibroblast growth factor receptor homolog 2

Genular Protein ID: 3965544932

Symbol: FGFR2_DROME

Name: Fibroblast growth factor receptor homolog 2

UniProtKB Accession Codes:

Q09147 A4V1Y3 Q712V2 Q9VUC8

Database IDs:

Citations:

PubMed ID: 8330538

Title: Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos.

PubMed ID: 8330538

DOI: 10.1242/dev.117.2.751

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 1325393

Title: Breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.

PubMed ID: 1325393

DOI: 10.1101/gad.6.9.1668

PubMed ID: 1849109

Title: The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension.

PubMed ID: 1849109

DOI: 10.1101/gad.5.4.697

PubMed ID: 1915852

Title: Identification of seven novel protein-tyrosine kinase genes of Drosophila by the polymerase chain reaction.

PubMed ID: 1915852

DOI: 10.1016/0014-5793(91)81078-m

PubMed ID: 9731193

Title: Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA.

PubMed ID: 9731193

DOI: 10.1006/bbrc.1998.9003

Sequence Information:

Length: 1052
Mass: 117813
Checksum: 74FBB9A5A2154D55
Sequence:

MAKVPITLVM IIAIVSAAAD LGCDYGHHRC YIDVTVENSP RQRHLLSDMD ITLQCVRPMA 
KWFYEDKFQL RATLLRLERA QSGNSGNYGC LDSQNRWYNI SLVVGHKEPV GNDIASFVKL 
EDAPALPESD LFFQPLNESR SLKLLQPLPK TVQRTAGGLF QLNCSPMDPD AKGVNISWLH 
NDTQILGGRG RIKLKRWSLT VGQLQPEDAG SYHCELCVEQ DCQRSNPTQL EVISRKHTVP 
MLKPGYPRNT SIALGDNVSI ECLLEDSALE PKITWLHKGN ADNIDDLLQR LREQSQLPVD 
VTRLITRMDE PQVLRLGNVL MEDGGWYICI AENQVGRTVA ASYVDLYSPS DTTTVRTTTT 
TTVASPIPTA STGEDNDDDV ENPAAEASGG VGPPVFRKEL KRLQHSLSGN TVNLACPVYG 
KANITWTKDK KPLNRELGVY VQKNWTLRFV EATSEDSGLY NCKVCNAWGC IQFDFSVQIN 
DRTRSAPIIV VPQNQTVKVN GSLVMKCTVY SDLHPTVSWK RVVLKNASLD GLKSVEIQNL 
NFTVTNDSVV LTLRNVTFDQ EGWYTCLASS GLGRSNSSVY LRVVSPLPPL EIYALLHAHP 
LGFTLAAITI VALFLLGSAF ITFMLRRLRR EKLLKLRIET VHQWTKKVII YRPGGEEGSG 
CSSGDLQMPV IRIEKQRTTV STTGTGGTDP AQGFNEYEFP LDSNWEIPRQ QLSLGSILGE 
GAFGRVVMAE AEGLPRSPQL AETIVAVKMV KEEHTDTDMA SLVREMEVMK MIGKHINIIN 
LLGCCSQGGP LWVIVEYAPH GNLKDFLKQN RPGAPQRRSD SDGYLDDKPL ISTQHLGEKE 
LTKFAFQIAR GMEYLASRRC IHRDLAARNV LVSDGYVMKI ADFGLARDIQ DTEYYRKNTN 
GRLPIKWMAP ESLQEKKYDS QSDVWSYGVL LWEIMTYGDQ PYPHILSAEE LYSYLITGQR 
MEKPAKCSLN IYVVMRQCWH FESCARPTFA ELVESFDGIL QQASSNPNDA YLDLSMPMLE 
TPPSSGDEDD GSDTETFRET SPLRYQYTYK FN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: btl

Associated with

Other Information

Two FGF-receptor homologues of Drosophila: one is expressed in mesodermal primordium in early embryos. PubMed ID: 8330538

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

Breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. PubMed ID: 1325393

The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension. PubMed ID: 1849109

Identification of seven novel protein-tyrosine kinase genes of Drosophila by the polymerase chain reaction. PubMed ID: 1915852

Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA. PubMed ID: 9731193