Details for: AGO2

Gene ID: 39683

Symbol: AGO2

Ensembl ID: FBgn0087035

Description: Argonaute 2

Associated with

Other Information

Genular Protein ID: 2702962030

Symbol: AGO2_DROME

Name: Protein argonaute-2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 16546082

Title: Natural selection drives extremely rapid evolution in antiviral RNAi genes.

PubMed ID: 16546082

DOI: 10.1016/j.cub.2006.01.065

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 11498593

Title: Argonaute2, a link between genetic and biochemical analyses of RNAi.

PubMed ID: 11498593

DOI: 10.1126/science.1064023

PubMed ID: 14508492

Title: A micrococcal nuclease homologue in RNAi effector complexes.

PubMed ID: 14508492

DOI: 10.1038/nature01956

PubMed ID: 12368261

Title: A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

PubMed ID: 12368261

DOI: 10.1101/gad.1022002

PubMed ID: 17178403

Title: Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies.

PubMed ID: 17178403

DOI: 10.1016/j.neuron.2006.10.028

PubMed ID: 20400949

Title: Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila.

PubMed ID: 20400949

DOI: 10.1038/nsmb.1810

PubMed ID: 26257286

Title: TAF11 Assembles the RISC Loading Complex to Enhance RNAi Efficiency.

PubMed ID: 26257286

DOI: 10.1016/j.molcel.2015.07.006

PubMed ID: 32504809

Title: Roles for Drosophila cap1 2'-O-ribose methyltransferase in the small RNA silencing pathway associated with Argonaute 2.

PubMed ID: 32504809

DOI: 10.1016/j.ibmb.2020.103415

PubMed ID: 14625589

Title: The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes.

PubMed ID: 14625589

DOI: 10.1038/nsb1016

PubMed ID: 14615801

Title: Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain.

PubMed ID: 14615801

DOI: 10.1038/nature02123

PubMed ID: 15156196

Title: Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.

PubMed ID: 15156196

DOI: 10.1038/nsmb777

Sequence Information:

  • Length: 1214
  • Mass: 136850
  • Checksum: 0DC73AF09CC33F73
  • Sequence:
  • MGKKDKNKKG GQDSAAAPQP QQQQKQQQQR QQQPQQLQQP QQLQQPQQLQ QPQQQQQQQP 
    HQQQQQSSRQ QPSTSSGGSR ASGFQQGGQQ QKSQDAEGWT AQKKQGKQQV QGWTKQGQQG 
    GHQQGRQGQD GGYQQRPPGQ QQGGHQQGRQ GQEGGYQQRP PGQQQGGHQQ GRQGQEGGYQ 
    QRPSGQQQGG HQQGRQGQEG GYQQRPPGQQ QGGHQQGRQG QEGGYQQRPS GQQQGGHQQG 
    RQGQEGGYQQ RPPGQQQGGH QQGRQGQEGG YQQRPPGQQQ GGHEQGRQGQ EGGYQQRPSG 
    QQQGGHQQGR QGQEGGYQQR PSGQQQGGHQ QGRQGQEGGY QQRPSGQQQG GHQQGRQGQE 
    GGYQQRPPGQ QPNQTQSQGQ YQSRGPPQQQ QAAPLPLPPQ PAGSIKRGTI GKPGQVGINY 
    LDLDLSKMPS VAYHYDVKIM PERPKKFYRQ AFEQFRVDQL GGAVLAYDGK ASCYSVDKLP 
    LNSQNPEVTV TDRNGRTLRY TIEIKETGDS TIDLKSLTTY MNDRIFDKPM RAMQCVEVVL 
    ASPCHNKAIR VGRSFFKMSD PNNRHELDDG YEALVGLYQA FMLGDRPFLN VDISHKSFPI 
    SMPMIEYLER FSLKAKINNT TNLDYSRRFL EPFLRGINVV YTPPQSFQSA PRVYRVNGLS 
    RAPASSETFE HDGKKVTIAS YFHSRNYPLK FPQLHCLNVG SSIKSILLPI ELCSIEEGQA 
    LNRKDGATQV ANMIKYAATS TNVRKRKIMN LLQYFQHNLD PTISRFGIRI ANDFIVVSTR 
    VLSPPQVEYH SKRFTMVKNG SWRMDGMKFL EPKPKAHKCA VLYCDPRSGR KMNYTQLNDF 
    GNLIISQGKA VNISLDSDVT YRPFTDDERS LDTIFADLKR SQHDLAIVII PQFRISYDTI 
    KQKAELQHGI LTQCIKQFTV ERKCNNQTIG NILLKINSKL NGINHKIKDD PRLPMMKNTM 
    YIGADVTHPS PDQREIPSVV GVAASHDPYG ASYNMQYRLQ RGALEEIEDM FSITLEHLRV 
    YKEYRNAYPD HIIYYRDGVS DGQFPKIKNE ELRCIKQACD KVGCKPKICC VIVVKRHHTR 
    FFPSGDVTTS NKFNNVDPGT VVDRTIVHPN EMQFFMVSHQ AIQGTAKPTR YNVIENTGNL 
    DIDLLQQLTY NLCHMFPRCN RSVSYPAPAY LAHLVAARGR VYLTGTNRFL DLKKEYAKRT 
    IVPEFMKKNP MYFV

Genular Protein ID: 3481124004

Symbol: M9PFK7_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 787
  • Mass: 90275
  • Checksum: 9AA8DD10BCC7896C
  • Sequence:
  • MPSVAYHYDV KIMPERPKKF YRQAFEQFRV DQLGGAVLAY DGKASCYSVD KLPLNSQNPE 
    VTVTDRNGRT LRYTIEIKET GDSTIDLKSL TTYMNDRIFD KPMRAMQCVE VVLASPCHNK 
    AIRVGRSFFK MSDPNNRHEL DDGYEALVGL YQAFMLGDRP FLNVDISHKS FPISMPMIEY 
    LERFSLKAKI NNTTNLDYSR RFLEPFLRGI NVVYTPPQSF QSAPRVYRVN GLSRAPASSE 
    TFEHDGKKVT IASYFHSRNY PLKFPQLHCL NVGSSIKSIL LPIELCSIEE GQALNRKDGA 
    TQVANMIKYA ATSTNVRKRK IMNLLQYFQH NLDPTISRFG IRIANDFIVV STRVLSPPQV 
    EYHSKRFTMV KNGSWRMDGM KFLEPKPKAH KCAVLYCDPR SGRKMNYTQL NDFGNLIISQ 
    GKAVNISLDS DVTYRPFTDD ERSLDTIFAD LKRSQHDLAI VIIPQFRISY DTIKQKAELQ 
    HGILTQCIKQ FTVERKCNNQ TIGNILLKIN SKLNGINHKI KDDPRLPMMK NTMYIGADVT 
    HPSPDQREIP SVVGVAASHD PYGASYNMQY RLQRGALEEI EDMFSITLEH LRVYKEYRNA 
    YPDHIIYYRD GVSDGQFPKI KNEELRCIKQ ACDKVGCKPK ICCVIVVKRH HTRFFPSGDV 
    TTSNKFNNVD PGTVVDRTIV HPNEMQFFMV SHQAIQGTAK PTRYNVIENT GNLDIDLLQQ 
    LTYNLCHMFP RCNRSVSYPA PAYLAHLVAA RGRVYLTGTN RFLDLKKEYA KRTIVPEFMK 
    KNPMYFV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.