Details for: eIF3e

Gene ID: 39877

Symbol: eIF3e

Ensembl ID: FBgn0025582

Description: eukaryotic translation initiation factor 3 subunit e

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-DME-72662)
  • Cap-dependent translation initiation
    (R-DME-72737)
  • Eukaryotic translation initiation
    (R-DME-72613)
  • Formation of a pool of free 40s subunits
    (R-DME-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-DME-72695)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-DME-156827)
  • Metabolism of proteins
    (R-DME-392499)
  • Ribosomal scanning and start codon recognition
    (R-DME-72702)
  • Translation
    (R-DME-72766)
  • Translation initiation complex formation
    (R-DME-72649)
  • Cytoplasm
    (GO:0005737)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Nucleus
    (GO:0005634)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)

Other Information

Genular Protein ID: 1279962195

Symbol: EIF3E_DROME

Name: N/A

UniProtKB Accession Codes:

O77410 Q9VVA2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 3 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 10 GeneTree 1 Genevisible 1 GenomeRNAi 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 5 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10375641

Title: Characterization of the Drosophila ortholog of mouse eIF-3p48/INT-6.

PubMed ID: 10375641

DOI: 10.1016/s0378-1119(99)00130-4

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 10731138

Title: A Drosophila complementary DNA resource.

PubMed ID: 10731138

DOI: 10.1126/science.287.5461.2222

PubMed ID: 18493598

Title: The proto-oncogene Int6 is essential for neddylation of Cul1 and Cul3 in Drosophila.

PubMed ID: 18493598

DOI: 10.1371/journal.pone.0002239

PubMed ID: 23716590

Title: Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster.

PubMed ID: 23716590

DOI: 10.1128/mcb.01354-12

PubMed ID: 28505193

Title: The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure.

PubMed ID: 28505193

DOI: 10.1371/journal.pgen.1006784

Sequence Information:

  • Length: 435
  • Mass: 51162
  • Checksum: 6F79D32FBA3EA711
  • Sequence:
    • MANFDLTRIN CQFLDRHLTF PLLEFLCGKE IYNQQELLEY ILETVNKTNM IDYTMDTRKR 
LNLSQEMPEE LVQRKAEVLA TLKQLQNEVA PIMKATDILK NGESMKDSKT FVNALQKDYN 
FKVEHLESAY KLAKYLYECG NYQESTSYLY FCLIVMSPND KNYLNVLWGK LAAEILTLNW 
NTALEDLTRL RDYIDNANFS TIQALQQRTW LIHWSVLVFF NHPKGRDLII EMFLYKPLYL 
NAIQTMCPHI MRYLATAVVI NRTRRNALKD LIKVIQQESY TYRDPITEFL ECLYVNFDFE 
GARLKLHECQ TVILNDFFIV ACLNEFVEDA RLMIFETFCR IHQCITISML ADKLNMKPNE 
AECWIVNLIR NARLNAKIDS KLGHVVMGTQ PLSPYQQLVE KIDSLSMRSE HLAGLIERKS 
KQKQNQESAD SWKYY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.