sina | FBgn0003410 | NCBI 39884

Details for: sina

Gene ID: 39884

Symbol: sina

Ensembl ID: FBgn0003410

Description: seven in absentia

Associated with

Adaptive immune system
(R-DME-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-DME-983168)
Axon guidance
(R-DME-422475)
Class i mhc mediated antigen processing & presentation
(R-DME-983169)
Deubiquitination
(R-DME-5688426)
Developmental biology
(R-DME-1266738)
Immune system
(R-DME-168256)
Metabolism of proteins
(R-DME-392499)
Nervous system development
(R-DME-9675108)
Netrin-1 signaling
(R-DME-373752)
Post-translational protein modification
(R-DME-597592)
Ub-specific processing proteases
(R-DME-5689880)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enteroendocrine cell differentiation
(GO:0035883)
Nucleus
(GO:0005634)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Proteasomal protein catabolic process
(GO:0010498)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)
R7 cell fate commitment
(GO:0007465)
Regulation of r7 cell differentiation
(GO:0045676)
Sensory organ development
(GO:0007423)
Sevenless signaling pathway
(GO:0045500)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase sina

Genular Protein ID: 1075159690

Symbol: SINA_DROME

Name: E3 ubiquitin-protein ligase sina

UniProtKB Accession Codes:

P21461 A4V214 Q9VVB0

Database IDs:

Citations:

PubMed ID: 2146028

Title: Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

PubMed ID: 2146028

DOI: 10.1016/0092-8674(90)90452-k

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 9267026

Title: PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.

PubMed ID: 9267026

DOI: 10.1016/s0092-8674(00)80506-1

PubMed ID: 9267027

Title: Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack.

PubMed ID: 9267027

DOI: 10.1016/s0092-8674(00)80507-3

PubMed ID: 11032805

Title: A role for Ebi in neuronal cell cycle control.

PubMed ID: 11032805

DOI: 10.1093/emboj/19.20.5376

PubMed ID: 11526076

Title: A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny.

PubMed ID: 11526076

DOI: 10.1242/dev.128.14.2699

PubMed ID: 12215542

Title: Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack.

PubMed ID: 12215542

DOI: 10.1128/mcb.22.19.6854-6865.2002

PubMed ID: 18160715

Title: Deubiquitylating enzyme UBP64 controls cell fate through stabilization of the transcriptional repressor tramtrack.

PubMed ID: 18160715

DOI: 10.1128/mcb.01567-07

Sequence Information:

Length: 314
Mass: 33707
Checksum: B58D7D5E8DA2F958
Sequence:

MSNKINPKRR EPTAAAAGAG ATGVATNTST STGSSSAGNT SSANTSSSSS SSLSSAGGGD 
AGMSADLTSL FECPVCFDYV LPPILQCSSG HLVCVSCRSK LTCCPTCRGP LANIRNLAME 
KVASNVKFPC KHSGYGCTAS LVYTEKTEHE ETCECRPYLC PCPGASCKWQ GPLDLVMQHL 
MMSHKSITTL QGEDIVFLAT DINLPGAVDW VMMQSCFGHH FMLVLEKQEK YDGHQQFFAI 
VQLIGSRKEA ENFVYRLELN GNRRRLTWEA MPRSIHEGVA SAIHNSDCLV FDTSIAQLFA 
DNGNLGINVT ISLV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: sina

Associated with

Other Information

Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye. PubMed ID: 2146028

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. PubMed ID: 9267026

Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack. PubMed ID: 9267027

A role for Ebi in neuronal cell cycle control. PubMed ID: 11032805

A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny. PubMed ID: 11526076

Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack. PubMed ID: 12215542

Deubiquitylating enzyme UBP64 controls cell fate through stabilization of the transcriptional repressor tramtrack. PubMed ID: 18160715