Details for: Nca

Gene ID: 40186

Symbol: Nca

Ensembl ID: FBgn0013303

Description: Neurocalcin

Associated with

  • Activation of ca-permeable kainate receptor
    (R-DME-451308)
  • Activation of kainate receptors upon glutamate binding
    (R-DME-451326)
  • Ionotropic activity of kainate receptors
    (R-DME-451306)
  • Neuronal system
    (R-DME-112316)
  • Neurotransmitter receptors and postsynaptic signal transmission
    (R-DME-112314)
  • Transmission across chemical synapses
    (R-DME-112315)
  • Calcium ion binding
    (GO:0005509)
  • Negative regulation of neuronal signal transduction
    (GO:1902848)
  • Positive regulation of circadian sleep/wake cycle, sleep
    (GO:0045938)

Other Information

Genular Protein ID: 1145568467

Symbol: NCAH_DROME

Name: Neurocalcin homolog

UniProtKB Accession Codes:

P42325 Q9VW67

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 15 DIP 1 DNASU 1 EMBL 3 EnsemblMetazoa 1 FlyBase 1 GO 3 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhylomeDB 1 Proteomes 1 Reactome 2 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 7989365

Title: A highly conserved homologue of bovine neurocalcin in Drosophila melanogaster is a Ca(2+)-binding protein expressed in neuronal tissues.

PubMed ID: 7989365

DOI: 10.1016/s0021-9258(18)31780-0

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 8626592

Title: Drosophila neurocalcin, a fatty acylated, Ca2+-binding protein that associates with membranes and inhibits in vitro phosphorylation of bovine rhodopsin.

PubMed ID: 8626592

DOI: 10.1074/jbc.271.17.10256

PubMed ID: 30865587

Title: Neurocalcin regulates nighttime sleep and arousal in Drosophila.

PubMed ID: 30865587

DOI: 10.7554/elife.38114

Sequence Information:

  • Length: 190
  • Mass: 21894
  • Checksum: F1158FEB8CF13F64
  • Sequence:
    • MGKQNSKLKP EVLEDLKQNT EFTDAEIQEW YKGFLKDCPS GHLSVEEFKK IYGNFFPYGD 
ASKFAEHVFR TFDANGDGTI DFREFLCALS VTSRGKLEQK LKWAFSMYDL DGNGYISRQE 
MLEIVTAIYK MVGSVMKMPE DESTPEKRTD KIFRQMDRNK DGKLSLEEFI EGAKSDPSIV 
RLLQCDPQSH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.