polo | FBgn0003124 | NCBI 40232

Details for: polo

Gene ID: 40232

Symbol: polo

Ensembl ID: FBgn0003124

Description: polo

Associated with

Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-DME-176814)
Apc/c-mediated degradation of cell cycle proteins
(R-DME-174143)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-DME-174178)
Cell cycle
(R-DME-1640170)
Cell cycle, mitotic
(R-DME-69278)
Cyclin a/b1/b2 associated events during g2/m transition
(R-DME-69273)
Eml4 and nudc in mitotic spindle formation
(R-DME-9648025)
G2/m transition
(R-DME-69275)
Golgi cisternae pericentriolar stack reorganization
(R-DME-162658)
Mitotic g2-g2/m phases
(R-DME-453274)
Mitotic metaphase/anaphase transition
(R-DME-68881)
Mitotic metaphase and anaphase
(R-DME-2555396)
Mitotic prometaphase
(R-DME-68877)
Mitotic prophase
(R-DME-68875)
Mitotic telophase/cytokinesis
(R-DME-68884)
M phase
(R-DME-68886)
Phosphorylation of emi1
(R-DME-176417)
Phosphorylation of the apc/c
(R-DME-176412)
Polo-like kinase mediated events
(R-DME-156711)
Regulation of apc/c activators between g1/s and early anaphase
(R-DME-176408)
Regulation of mitotic cell cycle
(R-DME-453276)
Regulation of plk1 activity at g2/m transition
(R-DME-2565942)
Resolution of sister chromatid cohesion
(R-DME-2500257)
Actomyosin contractile ring assembly
(GO:0000915)
Astral microtubule nucleation
(GO:0030954)
Atp binding
(GO:0005524)
Attachment of mitotic spindle microtubules to kinetochore
(GO:0051315)
Centriole
(GO:0005814)
Centrosome
(GO:0005813)
Centrosome cycle
(GO:0007098)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Embryonic heart tube development
(GO:0035050)
Female meiosis ii
(GO:0007147)
Female meiotic nuclear division
(GO:0007143)
Kinetochore
(GO:0000776)
Kinetochore microtubule
(GO:0005828)
Larval somatic muscle development
(GO:0007526)
Male germline ring canal formation
(GO:0030726)
Male meiosis cytokinesis
(GO:0007112)
Male meiotic nuclear division
(GO:0007140)
Meiotic spindle midzone assembly
(GO:0051257)
Microtubule
(GO:0005874)
Midbody
(GO:0030496)
Mitotic cell cycle
(GO:0000278)
Mitotic spindle midzone
(GO:1990023)
Mitotic spindle organization
(GO:0007052)
Negative regulation of neuroblast proliferation
(GO:0007406)
Nuclear envelope
(GO:0005635)
Nucleus
(GO:0005634)
Oocyte fate commitment
(GO:0048600)
Outer kinetochore
(GO:0000940)
Pronuclear fusion
(GO:0007344)
Pronuclear migration
(GO:0035046)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein localization
(GO:0008104)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Sperm aster formation
(GO:0035044)
Spindle
(GO:0005819)
Spindle assembly involved in female meiosis ii
(GO:0007058)
Spindle pole
(GO:0000922)

Other Information

Proteins

Serine/threonine-protein kinase polo

Genular Protein ID: 3228940521

Symbol: POLO_DROME

Name: Serine/threonine-protein kinase polo

UniProtKB Accession Codes:

P52304 A4V258 Q9VWB2

Database IDs:

Citations:

PubMed ID: 1660828

Title: Polo encodes a protein kinase homolog required for mitosis in Drosophila.

PubMed ID: 1660828

DOI: 10.1101/gad.5.12a.2153

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 18327897

Title: Phosphoproteome analysis of Drosophila melanogaster embryos.

PubMed ID: 18327897

DOI: 10.1021/pr700696a

PubMed ID: 24829288

Title: Differing requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila.

PubMed ID: 24829288

DOI: 10.1098/rsob.140047

Sequence Information:

Length: 576
Mass: 66974
Checksum: 5022B9AC0E888FAD
Sequence:

MAAKPEDKST DIPDRLVDIN QRKTYKRMRF FGKGGFAKCY EIIDVETDDV FAGKIVSKKL 
MIKHNQKEKT AQEITIHRSL NHPNIVKFHN YFEDSQNIYI VLELCKKRSM MELHKRRKSI 
TEFECRYYIY QIIQGVKYLH DNRIIHRDLK LGNLFLNDLL HVKIGDFGLA TRIEYEGERK 
KTLCGTPNYI APEILTKKGH SFEVDIWSIG CVMYTLLVGQ PPFETKTLKD TYSKIKKCEY 
RVPSYLRKPA ADMVIAMLQP NPESRPAIGQ LLNFEFLKGS KVPMFLPSSC LTMAPRIGSN 
DTIEDSMHRK PLMEMNGIRP DDTRLESTFL KANLHDAITA SAQVCRHSED YRSDIESLYQ 
QLTNLINGKP RILQGNLGDE NTDPAAQPLF WISKWVDYSD KYGFGYQLCD EGIGVMFNDT 
TKLILLPNQI NVHFIDKDGK ETYMTTTDYC KSLDKKMKLL SYFKRYMIEH LVKAGANNVN 
IESDQISRMP HLHSWFRTTC AVVMHLTNGS VQLNFSDHMK LILCPRMSAI TYMDQEKNFR 
TYRFSTIVEN GVSKDLYQKI RYAQEKLRKM LEKMFT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: polo

Associated with

Other Information

Polo encodes a protein kinase homolog required for mitosis in Drosophila. PubMed ID: 1660828

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila full-length cDNA resource. PubMed ID: 12537569

Phosphoproteome analysis of Drosophila melanogaster embryos. PubMed ID: 18327897