Details for: isoQC

Gene ID: 40270

Symbol: isoQC

Description: iso Glutaminyl cyclase

Associated with

  • Extracellular region
    (GO:0005576)
  • Glutaminyl-peptide cyclotransferase activity
    (GO:0016603)
  • Mitochondrion
    (GO:0005739)
  • Peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
    (GO:0017186)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 3863785012

Symbol: QPCT2_DROME

Name: N/A

UniProtKB Accession Codes:

Q86PD7 Q7KTY3

Database IDs:

AlphaFoldDB 1 BRENDA 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 EC 1 EMBL 6 EnsemblMetazoa 2 ExpressionAtlas 1 FlyBase 2 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PaxDb 1 Pfam 1 Proteomes 2 Reactome 1 RefSeq 2 Rhea 3 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 17722885

Title: Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.

PubMed ID: 17722885

DOI: 10.1021/bi701043x

PubMed ID: 22897232

Title: Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs.

PubMed ID: 22897232

DOI: 10.1021/bi300687g

Sequence Information:

  • Length: 354
  • Mass: 40838
  • Checksum: 4E5024991A72B175
  • Sequence:
    • MRLLLRNYSL MEAVKRLLPR PRKKIYNLGA CFELVDIPKI SYNPSELSEP RFLEYSNLSD 
KLHLREAIDK ILIPRVVGTT NHSIVREYIV QSLRDLDWDV EVNSFHDHAP IKGKLHFHNI 
IATLNPNAER YLVLSCHYDS KYMPGVEFLG ATDSAVPCAM LLNLAQVLQE QLKPLKKSKL 
SLMLLFFDGE EAFEEWGPKD SIYGARHLAK KWHHEGKLDR IDMLVLLDLL GAPDPAFYSF 
FENTESWYMR IQSVETRLAK LQLLERYASS GVAQRDPTRY FQSQAMRSSF IEDDHIPFLR 
RNVPILHLIP VPFPSVWHTP DDNASVIDYA TTDNLALIIR LFALEYLLAG TEAK

Genular Protein ID: 3593595400

Symbol: Q0GT99_DROME

Name: N/A

UniProtKB Accession Codes:

Q0GT99

Database IDs:

AGR 1 ARBA 5 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 ChiTaRS 1 DNASU 1 EC 1 EMBL 30 GO 1 Gene3D 1 GenomeRNAi 1 HOGENOM 1 InterPro 3 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 2 RefSeq 1 Rhea 3 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 16783023

Title: Molecular evolution and population genetic analysis of candidate female reproductive genes in Drosophila.

PubMed ID: 16783023

DOI: 10.1534/genetics.105.053611

Sequence Information:

  • Length: 352
  • Mass: 40336
  • Checksum: AC2F77245C114ACE
  • Sequence:
    • MLHRTARMWT LCVQTALIAT LVRGSTSQKD NLVGRTQISY NPSELSEPRF LEYSNLSDKL 
HLREAIDKIL IPRVVGTTNH SIVREYIVQS LRDLDWDVEV NSFHDHAPIK GKLHFHNIIA 
TLNPNAERYL VLSCHYDSKY MPGVEFLGAT DSAVPCAMLL NLAQVLQEQL KPLKKSKLSL 
MLLFFDGEEA FEEWGPKDSI YGARHLAKKW HHEGKLDRID MLVLLDLLGA PDPAFYSFFE 
NTESWYMRIQ SVETRLAKLQ LLERYASSGV AQRDPTRYFQ SQAMRSSFIE DDHIPFLRRN 
VPILHLIPVP FPSVWHTPDD NASVIDYATT DNLALIIRLF ALEYLLAGTE AK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.