Pc | FBgn0003042 | NCBI 40358

Details for: Pc

Gene ID: 40358

Symbol: Pc

Ensembl ID: FBgn0003042

Description: Polycomb

Associated with

Cellular responses to stimuli
(R-DME-8953897)
Cellular responses to stress
(R-DME-2262752)
Cellular senescence
(R-DME-2559583)
Gene expression (transcription)
(R-DME-74160)
Generic transcription pathway
(R-DME-212436)
Intracellular signaling by second messengers
(R-DME-9006925)
Metabolism of proteins
(R-DME-392499)
Oxidative stress induced senescence
(R-DME-2559580)
Pip3 activates akt signaling
(R-DME-1257604)
Post-translational protein modification
(R-DME-597592)
Pten regulation
(R-DME-6807070)
Regulation of pten gene transcription
(R-DME-8943724)
Rna polymerase ii transcription
(R-DME-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-DME-8939243)
Signal transduction
(R-DME-162582)
Sumo e3 ligases sumoylate target proteins
(R-DME-3108232)
Sumoylation
(R-DME-2990846)
Sumoylation of dna damage response and repair proteins
(R-DME-3108214)
Sumoylation of rna binding proteins
(R-DME-4570464)
Sumoylation of transcription cofactors
(R-DME-3899300)
Transcriptional regulation by runx1
(R-DME-8878171)
Anterior/posterior axis specification
(GO:0009948)
Chromatin
(GO:0000785)
Chromatin binding
(GO:0003682)
Dna binding
(GO:0003677)
Heterochromatin formation
(GO:0031507)
Methylated histone binding
(GO:0035064)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of response to gamma radiation
(GO:2001229)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neurogenesis
(GO:0022008)
Neuron remodeling
(GO:0016322)
Nucleolus
(GO:0005730)
Nucleus
(GO:0005634)
Polytene chromosome
(GO:0005700)
Polytene chromosome band
(GO:0005704)
Prc1 complex
(GO:0035102)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Sequence-specific dna binding
(GO:0043565)
Specification of segmental identity, abdomen
(GO:0007385)
Syncytial blastoderm mitotic cell cycle
(GO:0035186)
Ventral cord development
(GO:0007419)
Wound healing
(GO:0042060)

Other Information

Proteins

Polycomb group protein Pc

Genular Protein ID: 788575668

Symbol: PC_DROME

Name: Polycomb group protein Pc

UniProtKB Accession Codes:

P26017 Q9VP49

Database IDs:

Citations:

PubMed ID: 1898775

Title: The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.

PubMed ID: 1898775

DOI: 10.1073/pnas.88.1.263

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 11493925

Title: A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

PubMed ID: 11493925

DOI: 10.1038/35088096

PubMed ID: 11583617

Title: Reconstitution of a functional core polycomb repressive complex.

PubMed ID: 11583617

DOI: 10.1016/s1097-2765(01)00316-1

PubMed ID: 27326929

Title: Stuxnet facilitates the degradation of polycomb protein during development.

PubMed ID: 27326929

DOI: 10.1016/j.devcel.2016.05.013

PubMed ID: 30078725

Title: Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons.

PubMed ID: 30078725

DOI: 10.1016/j.molcel.2018.07.005

PubMed ID: 31784359

Title: Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression.

PubMed ID: 31784359

DOI: 10.1016/j.molcel.2019.10.017

Sequence Information:

Length: 390
Mass: 43976
Checksum: 5DB24AE4B326C3B9
Sequence:

MTGRGKGSKG KLGRDNATDD PVDLVYAAEK IIQKRVKKGV VEYRVKWKGW NQRYNTWEPE 
VNILDRRLID IYEQTNKSSG TPSKRGIKKK EKEPDPEPES EEDEYTFTEN DVDTHQATTS 
SATHDKESKK EKKHHHHHHH HHHIKSERNS GRRSESPLTH HHHHHHHESK RQRIDHSSSS 
NSSFTHNSFV PEPDSNSSSS EDQPLIGTKR KAEVLKESGK IGVTIKTSPD GPTIKPQPTQ 
QVTPSQQQPF QDQQQAEKIA SEAATQLKSE QQATPLATEA INTTPAESGA EEEEVANEEG 
NQQAPQVPSE NNNIPKPCNN LAINQKQPLT PLSPRALPPR FWLPAKCNIS NRVVITDVTV 
NLETVTIREC KTERGFFRER DMKGDSSPVA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pc

Associated with

Other Information

The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. PubMed ID: 1898775

The genome sequence of Drosophila melanogaster. PubMed ID: 10731132

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. PubMed ID: 12537572

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. PubMed ID: 11493925

Reconstitution of a functional core polycomb repressive complex. PubMed ID: 11583617

Stuxnet facilitates the degradation of polycomb protein during development. PubMed ID: 27326929

Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons. PubMed ID: 30078725

Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression. PubMed ID: 31784359