Details for: Wnk

Gene ID: 40391

Symbol: Wnk

Ensembl ID: FBgn0037098

Description: Wnk kinase

Associated with

Other Information

Genular Protein ID: 3685054530

Symbol: WNK_DROME

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537569

Title: A Drosophila full-length cDNA resource.

PubMed ID: 12537569

DOI: 10.1186/gb-2002-3-12-research0080

PubMed ID: 23797875

Title: Wnk kinases are positive regulators of canonical Wnt/beta-catenin signalling.

PubMed ID: 23797875

DOI: 10.1038/embor.2013.88

PubMed ID: 25086033

Title: Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.

PubMed ID: 25086033

DOI: 10.1074/jbc.m114.577767

PubMed ID: 33439774

Title: WNKs are potassium-sensitive kinases.

PubMed ID: 33439774

DOI: 10.1152/ajpcell.00456.2020

PubMed ID: 36318922

Title: WNK kinases sense molecular crowding and rescue cell volume via phase separation.

PubMed ID: 36318922

DOI: 10.1016/j.cell.2022.09.042

PubMed ID: 35303418

Title: Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade.

PubMed ID: 35303418

DOI: 10.1016/j.cub.2022.03.017

Sequence Information:

  • Length: 2462
  • Mass: 272850
  • Checksum: E0ED3DDC14AB632F
  • Sequence:
  • MGQTLCDFVR QQEVVPANRA RKGSAISEDG TTSCTTQPQR NTSISSEEQT VQGANIQKSG 
    HRSFNRSASS RQKPNPTSKL KDTLNRKPTC KQGTLSAHTS TSSTTSIQSS PIEPASSLPT 
    LNTTPTPPAA SKSNLFVRVL RRFSNNTLPG KTASSPKNVD DVPKVNDNNN GDLGKQQSTD 
    VEVLCSQDNQ SREQNEDEMD SKIEPADAIS NQKAGLTSGK PKKDKSVKGT SQAVVSDTKK 
    MEARKSSSDT VIEPLIKQQA PLHSSKTTPT TLTANFVQNI RFVRKNVEQS GRNTNPLQFV 
    ELETEFPRDY DDNIEMLSRE AEHLEEQFRT PTRSNATDAT SHHVAGIIDN IITEASRSLT 
    IEKTEDDVPL KSSTKHSSGV KRVGFQVEDK DDTEVQSEKQ AKSFDDITKK AESSEASAEE 
    AAVTGSSTDA SASPLPSTSL VSTTSSATSI TKSKSDEDDD PVAMSPCGRF FKYDKEVGRG 
    SFKTVYRGLD TLTGVPVAWC ELLDKQVKKS ERTRFREEAD MLKKLQHPNI VRFYTYWEFP 
    IGRKKNIVLV TELMLSGTLK SYLKRFKKIH PKVLKSWCRQ ILKGLNFLHT RQFPIIHRDL 
    KCDNIFITGT TGSVKIGDLG LATLKNRSHA KSVIGTPEFM APEMYEEHYD ESVDVYAFGM 
    CMLEMAISEY PYSECKGPAQ IYKKVISGIK PAALAKVEDP NVRDIIERCI ELKKEDRPSC 
    NELLESEFFD EDIGIRVEPT ASEQFLSDPS ISIIEFRLRF MDPKKRSSRH KENEAIQFEY 
    NIRHDEYEQI AQEMMKENII SEDDSRAVAR LLKVQVVSLL KERAQRQTQI KLQNEKSRLE 
    KLALQKQRES LPTNVDEDEE EEEESEDEED GVKWNQRLQL RYDLLNTDSE TSLALSTNSV 
    EPQQLSTRSN TSIPNSGIQQ PVQVPGQVPV SQLISVQPQA IPSPAIPMQQ KPTVHYIQPP 
    QLASYQNSNA SMQEMTNNQV ISPTGSQQMQ QQQPVVAPTV NHQVMPQQQV NQQQQQPQMM 
    QQIPQQVQVQ QPQTVLPPQP HEQQPQQQQQ PLQQQLQQLM HTNVQAPDLT QQQQMAQQQA 
    QQYFQQQQQQ PQQAVNMQQA YAMQQAGQQQ QLSQPLQIQQ QILQQQQVAV SHQQQIMQQQ 
    LAQHQLQQLQ QQQLQQQQLQ QQQQIQQQQL QQQQLQQQQF VQQYAQAMPQ QQHQQLVTGS 
    QVMAPHQHQQ PIQIPVQMQV PPTSVAPPIQ HTYNQQGGQV TLSDAQQQQH PGFSAVPQQA 
    APFIQQPTQQ PIQLSMPLEQ QLQQLLHSQP AQQQQAMSQQ QQQPLVQQQQ LPLVQQQPPL 
    VQQQQPLVQH QQPSVQHQQP LVQQPQQQQP QPQNQQPQPQ TQQTHVVQQQ PPQQQPAVEQ 
    ISQISSQVPV QQENLQPIQV NKDANVATDA MSLNSAHGAL EPAPKTEPQN SADAEKQQKQ 
    TGTGTRSQKP RRSNRSGNER IPKLSVTSVD EGSVINCHME NKLKTITFKF DIGDVNPVEI 
    ANKLIAQDLL SNCQSTVFVE MINEIVDQVK QNPNQIPIPT NYRRNIEKVR HASLTRQRST 
    FRSHQRHRSR DETASDITKM FEPTIHGVET LPSGGGGAEQ SNCNLTLEAR SHLSNIPNAK 
    EPQLNVSTPP TTTSTMSSSS TASRDAPNSS NDVTIGSGSV SRKTSTASEY TSLSIDYMPD 
    SNITPTGPEP PLDDGKDKKP CSLAIARMQK LLESAGNGAP RSLNLPLNRH LKIQEDLKHT 
    RSLDDLTAVK ITFDMPNKAA LDTSENAQQA TEAEAEKPKD KSGQAVGNQG TGAANTLEQL 
    KIELENITHA HAFASAVVAS INNRAPHQAS PAMSSLKATS GQPQTQEITK PNNGAGPSVP 
    SVGQNTPTAA LTSARGSGSS VYNSRRTSID NSVGSDMHLH TATNLEGTVS NPDPIPTEAS 
    VGITIATGHE KQLSKQPSLE KPSATSILTN NSDPPQRNPS NGSINQNSIA DLEKKLAALR 
    NTENTEESAT ATLSVVPKQV EEVVNPSARK ISRFSVSRVQ EQKTSTGVEE PAQGQLKIDL 
    QVAGPGGQVQ TNNSVQNGSV VNTPTEVISS PIQNVPLAIN GIQLMYQQPQ QIHQLPGGTS 
    TTTSGAGTQC IVVPQVVNQN GTHVQQPSNL QPQQQSVHPN MTQQPQQTPL NGHPSMVNTL 
    QQQPPQQSLP MQTIQSQQQQ HNQMPIISQQ QQQQILMQQQ QQQGSQQGSQ QFNLPGTQQT 
    HPQHQFIQSQ PNQLHSLPPQ VVSMAQGNLP HQLPPMQTMG AQQQMISQQQ HQLQMQSHMH 
    QQNVPGMYNQ QTGARVAAPQ NFAGAVPNHL LQQSPLMASQ QPAQPMQHVM QPIFNATSGE 
    VTEEPVSLAA THPHLLPSDI QSDIKHNLDS LVNQLCNTRL GTNQHQRLLL LRQRQLIEED 
    ELRLKHYVEY EKFQKALRQS ISTNVPANAA YYSAAAAQLP TNLAAPAAPS SSNPTSTSSA 
    NT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.