Details for: TfAP 2

Gene ID: 40398

Symbol: TfAP 2

Ensembl ID: FBgn0261953

Description: Transcription factor AP-2

Associated with

  • Activation of the tfap2 (ap-2) family of transcription factors
    (R-DME-8866907)
  • Developmental biology
    (R-DME-1266738)
  • Gastrulation
    (R-DME-9758941)
  • Gene expression (transcription)
    (R-DME-74160)
  • Generic transcription pathway
    (R-DME-212436)
  • Negative regulation of activity of tfap2 (ap-2) family transcription factors
    (R-DME-8866904)
  • Rna polymerase ii transcription
    (R-DME-73857)
  • Specification of the neural plate border
    (R-DME-9834899)
  • Tfap2 (ap-2) family regulates transcription of cell cycle factors
    (R-DME-8866911)
  • Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation
    (R-DME-8869496)
  • Transcriptional regulation by the ap-2 (tfap2) family of transcription factors
    (R-DME-8864260)
  • Adult feeding behavior
    (GO:0008343)
  • Adult locomotory behavior
    (GO:0008344)
  • Anatomical structure development
    (GO:0048856)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Imaginal disc-derived leg joint morphogenesis
    (GO:0016348)
  • Imaginal disc-derived leg morphogenesis
    (GO:0007480)
  • Imaginal disc-derived male genitalia development
    (GO:0007485)
  • Inter-male aggressive behavior
    (GO:0002121)
  • Male courtship behavior
    (GO:0008049)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Notch signaling pathway
    (GO:0007219)
  • Nucleus
    (GO:0005634)
  • Positive regulation of octopamine signaling pathway
    (GO:2000130)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Proboscis development
    (GO:0048728)
  • Regulation of cell population proliferation
    (GO:0042127)
  • Regulation of circadian sleep/wake cycle, sleep
    (GO:0045187)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)

Other Information

Genular Protein ID: 2248139505

Symbol: O76923_DROME

Name: N/A

UniProtKB Accession Codes:

O76923

Database IDs:

AGR 1 ARBA 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 4 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 18 GeneTree 1 GenomeRNAi 1 HOGENOM 1 IntAct 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 9867351

Title: DAP-2, the Drosophila homolog of transcription factor AP-2.

PubMed ID: 9867351

DOI: 10.1016/S0925-4773(98)00125-7

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 461
  • Mass: 50343
  • Checksum: 9A0FE9AE6EB4BEA1
  • Sequence:
    • MTLAYVDMPA VIQVQERLSG HGSLGLSSGS AAYTTHSGGH TGRSGPATGH SGHSSTHGSA 
ATMHHQSLQS DFQPPYFPPP FHHSTQSPPQ QQNHGALEYL GTDPYGQPLS SLHHAPLHHY 
NQLAGLRSTQ DQLGIHRTHR EAELQGHVTQ LSHGFPYTDR RSDYGSAISA GAAHGTRLGH 
EHESLALHQA LQNAVDDVQA PALDDNVAFM SDLPLIKSMK SGKEAGNIGS GSPSEVFCAV 
PGRLSLLSST SKYKVTIAEV QRRLSPPECL NASLLGGVLR RAKSKNGGRL LREKLEKIGL 
NLPAGRRKAA NVTLLTSLVE GEATHLAKDF HFVCETEFPA RQLAEYIVRH QTEPQDSYRR 
KELILHSQQI TKELMQILSQ DRTTHFGTRS QHLLEPSMQR HLTHFSLITH GFGSPAIMAV 
LHAFQTFLNE SLNYLEKLYP SNGGGMVSSS LDKSKIDNEK K

Genular Protein ID: 3512859956

Symbol: M9PG57_DROME

Name: N/A

UniProtKB Accession Codes:

M9PG57

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 18 GeneTree 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 459
  • Mass: 50105
  • Checksum: 56557269A0F646D4
  • Sequence:
    • MSFLATLDAS AWQERLSGHG SLGLSSGSAA YTTHSGGHTG RSGPATGHSG HSSTHGSAAT 
MHHQSLQSDF QPPYFPPPFH HSTQSPPQQQ NHGALEYLGT DPYGQPLSSL HHAPLHHYNQ 
LAGLRSTQDQ LGIHRTHREA ELQGHVTQLS HGFPYTDRRS DYGSAISAGA AHGTRLGHEH 
ESLALHQALQ NAVDDVQAPA LDDNVAFMSD LPLIKSMKSG KEAGNIGSGS PSEVFCAVPG 
RLSLLSSTSK YKVTIAEVQR RLSPPECLNA SLLGGVLRRA KSKNGGRLLR EKLEKIGLNL 
PAGRRKAANV TLLTSLVEGE ATHLAKDFHF VCETEFPARQ LAEYIVRHQT EPQDSYRRKE 
LILHSQQITK ELMQILSQDR TTHFGTRSQH LLEPSMQRHL THFSLITHGF GSPAIMAVLH 
AFQTFLNESL NYLEKLYPSN GGGMVSSSLD KSKIDNEKK

Genular Protein ID: 2924266216

Symbol: M9PD85_DROME

Name: N/A

UniProtKB Accession Codes:

M9PD85

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 18 GeneTree 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 467
  • Mass: 51005
  • Checksum: 7CCC1EB935758C3F
  • Sequence:
    • MTLAYVDMPA VIQVQERLSG HGSLGLSSGS AAYTTHSGGH TGRSGPATGH SGHSSTHGSA 
ATMHHQSLQS DFQPPYFPPP FHHSTQSPPQ QQISGYLQNH GALEYLGTDP YGQPLSSLHH 
APLHHYNQLA GLRSTQDQLG IHRTHREAEL QGHVTQLSHG FPYTDRRSDY GSAISAGAAH 
GTRLGHEHES LALHQALQNA VDDVQAPALD DNVAFMSDLP LIKSMKSGKE AGNIGSGSPS 
EVFCAVPGRL SLLSSTSKYK VTIAEVQRRL SPPECLNASL LGGVLRRAKS KNGGRLLREK 
LEKIGLNLPA GRRKAANVTL LTSLVEGEAT HLAKDFHFVC ETEFPARQLA EYIVRHQTEP 
QDSYRRKELI LHSQQITKEL MQILSQDRTT HFGTRSQHLL EPSMQRHLTH FSLITHGFGS 
PAIMAVLHAF QTFLNESLNY LEKLYPSNGG GMVSSSLDKS KIDNEKK

Genular Protein ID: 2975118458

Symbol: M9PFX8_DROME

Name: N/A

UniProtKB Accession Codes:

M9PFX8

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 18 GeneTree 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 VEuPathDB 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 465
  • Mass: 50767
  • Checksum: B02CB2F6C1B33065
  • Sequence:
    • MSFLATLDAS AWQERLSGHG SLGLSSGSAA YTTHSGGHTG RSGPATGHSG HSSTHGSAAT 
MHHQSLQSDF QPPYFPPPFH HSTQSPPQQQ ISGYLQNHGA LEYLGTDPYG QPLSSLHHAP 
LHHYNQLAGL RSTQDQLGIH RTHREAELQG HVTQLSHGFP YTDRRSDYGS AISAGAAHGT 
RLGHEHESLA LHQALQNAVD DVQAPALDDN VAFMSDLPLI KSMKSGKEAG NIGSGSPSEV 
FCAVPGRLSL LSSTSKYKVT IAEVQRRLSP PECLNASLLG GVLRRAKSKN GGRLLREKLE 
KIGLNLPAGR RKAANVTLLT SLVEGEATHL AKDFHFVCET EFPARQLAEY IVRHQTEPQD 
SYRRKELILH SQQITKELMQ ILSQDRTTHF GTRSQHLLEP SMQRHLTHFS LITHGFGSPA 
IMAVLHAFQT FLNESLNYLE KLYPSNGGGM VSSSLDKSKI DNEKK

Genular Protein ID: 1653651040

Symbol: O96378_DROME

Name: N/A

UniProtKB Accession Codes:

O96378

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 6 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 20 GeneTree 1 GenomeRNAi 1 IntAct 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 9788434

Title: Cloning and characterization of the Drosophila homologue of the AP-2 transcription factor.

PubMed ID: 9788434

DOI: 10.1038/sj.onc.1202114

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

PubMed ID: 26109357

Title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

PubMed ID: 26109357

DOI: .1534/g3.115.018929

PubMed ID: 26109356

Title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

PubMed ID: 26109356

DOI: .1534/g3.115.018937

PubMed ID: 25589440

Title: The Release 6 reference sequence of the Drosophila melanogaster genome.

PubMed ID: 25589440

Sequence Information:

  • Length: 465
  • Mass: 51123
  • Checksum: 39B3097EEDBC2502
  • Sequence:
    • MHILHRTNDH QFEDQKFMME RLSGHGSLGL SSGSAAYTTH SGGHTGRSGP ATGHSGHSST 
HGSAATMHHQ SLQSDFQPPY FPPPFHHSTQ SPPQQQNHGA LEYLGTDPYG QPLSSLHHAP 
LHHYNQLAGL RSTQDQLGIH RTHREAELQG HVTQLSHGFP YTDRRSDYGS AISAGAAHGT 
RLGHEHESLA LHQALQNAVD DVQAPALDDN VAFMSDLPLI KSMKSGKEAG NIGSGSPSEV 
FCAVPGRLSL LSSTSKYKVT IAEVQRRLSP PECLNASLLG GVLRRAKSKN GGRLLREKLE 
KIGLNLPAGR RKAANVTLLT SLVEGEATHL AKDFHFVCET EFPARQLAEY IVRHQTEPQD 
SYRRKELILH SQQITKELMQ ILSQDRTTHF GTRSQHLLEP SMQRHLTHFS LITHGFGSPA 
IMAVLHAFQT FLNESLNYLE KLYPSNGGGM VSSSLDKSKI DNEKK

Genular Protein ID: 2674227353

Symbol: M9PIH9_DROME

Name: N/A

UniProtKB Accession Codes:

M9PIH9

Database IDs:

AGR 1 ARBA 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 EnsemblMetazoa 1 ExpressionAtlas 1 FlyBase 2 GO 19 GeneTree 1 GenomeRNAi 1 InParanoid 1 IntAct 1 InterPro 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PaxDb 1 Pfam 2 Proteomes 2 Reactome 5 RefSeq 1 SAM 1 SMR 1 STRING 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10731132

Title: The genome sequence of Drosophila melanogaster.

PubMed ID: 10731132

DOI: 10.1126/science.287.5461.2185

PubMed ID: 12537568

Title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

PubMed ID: 12537568

PubMed ID: 12537572

Title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

PubMed ID: 12537572

DOI: 10.1186/gb-2002-3-12-research0083

PubMed ID: 12537573

Title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

PubMed ID: 12537573

PubMed ID: 12537574

Title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

PubMed ID: 12537574

PubMed ID: 16110336

Title: Combined evidence annotation of transposable elements in genome sequences.

PubMed ID: 16110336

DOI: 10.1371/journal.pcbi.0010022

PubMed ID: 17569856

Title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

PubMed ID: 17569856

DOI: 10.1126/science.1139815

PubMed ID: 17569867

Title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

PubMed ID: 17569867

DOI: 10.1126/science.1139816

Sequence Information:

  • Length: 471
  • Mass: 51785
  • Checksum: FE63C46479C9FF83
  • Sequence:
    • MHILHRTNDH QFEDQKFMME RLSGHGSLGL SSGSAAYTTH SGGHTGRSGP ATGHSGHSST 
HGSAATMHHQ SLQSDFQPPY FPPPFHHSTQ SPPQQQISGY LQNHGALEYL GTDPYGQPLS 
SLHHAPLHHY NQLAGLRSTQ DQLGIHRTHR EAELQGHVTQ LSHGFPYTDR RSDYGSAISA 
GAAHGTRLGH EHESLALHQA LQNAVDDVQA PALDDNVAFM SDLPLIKSMK SGKEAGNIGS 
GSPSEVFCAV PGRLSLLSST SKYKVTIAEV QRRLSPPECL NASLLGGVLR RAKSKNGGRL 
LREKLEKIGL NLPAGRRKAA NVTLLTSLVE GEATHLAKDF HFVCETEFPA RQLAEYIVRH 
QTEPQDSYRR KELILHSQQI TKELMQILSQ DRTTHFGTRS QHLLEPSMQR HLTHFSLITH 
GFGSPAIMAV LHAFQTFLNE SLNYLEKLYP SNGGGMVSSS LDKSKIDNEK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.